Results 121 to 130 of about 61,218 (243)

Chemogenetic Schwann cell activation impairs early myelination and triggers adult demyelination in the peripheral nervous system. [PDF]

Front Cell Neurosci
Corral JG, Cheli VT, Santiago-Gonzalez DA, Kedari KG, Paez PM.   +4 more
europepmc   +1 more source

Synaptic ultrastructural alterations in human focal cortical dysplasia: Insights from volume electron microscopy

Epilepsia, EarlyView.
Abstract Objective Focal cortical dysplasia (FCD) is a developmental malformation of the cerebral cortex and a leading cause of drug‐resistant epilepsy in children and young adults. Disruption of the excitation–inhibition (E–I) balance is a hallmark of neuronal hyperexcitability in FCD, yet the underlying synaptic ultrastructural changes remain poorly ...
Gyu Hyun Kim, Na‐Young Seo, Seung‐Ki Kim, Jae‐Kyung Won, Yang Hoon Huh, Ji Yeoun Lee, Kea Joo Lee   +6 more
wiley   +1 more source

The Fronto-Temporal Cortex Has Increased Subcortical Connectivity In Utero and Plasticity in Adulthood. [PDF]

J Neurosci
Epihova G, Epihov DZ, Akarca D, Astle DE.   +3 more
europepmc   +1 more source

The technical and practical implementation of fundus photography in equids

Equine Veterinary Education, EarlyView.
Summary Background Fundus photography is an important diagnostic tool in human and veterinary medicine. Advances in research are increasing its accessibility in human medicine. However, there is a lack of studies on modern fundus photography in animals, particularly in horses. Objectives To assess the use of a portable fundus camera developed for human
I. Vierling, B. Wollanke, V. Franzen
wiley   +1 more source

Annual Research Review: Neural mechanisms of eating disorders in youth – from current theory and findings to future directions

Journal of Child Psychology and Psychiatry, EarlyView.
Eating disorders are prevalent and profoundly debilitating psychiatric conditions with multifactorial etiology that frequently manifest during adolescence. This developmental stage is characterized by significant neurostructural and neurofunctional change, which may create a context conducive to the emergence of eating pathology.
Kelsey Hagan, E. Caitlin Lloyd, Sasha Gorrell   +2 more
wiley   +1 more source

Dysregulated lipid metabolism and hypomyelination in postnatal peroxisome-deficient <i>Pex2</i> knockout Zellweger mice. [PDF]

Front Mol Neurosci
Eberhart T, Charles KN, Salumbides-Torres B, Price N, Fliesler SJ, Faust PL, Kovacs WJ.   +6 more
europepmc   +1 more source

Elevated neurofilament light levels in acute anorexia nervosa are associated with alterations in white matter volume and connectivity networks

Journal of Child Psychology and Psychiatry, EarlyView.
Background Anorexia nervosa (AN) is a severe eating disorder associated with drastic reductions in gray and white matter (WM) volume and structural connectivity alterations. However, the hypotheses regarding underlying mechanisms are inconclusive. The current study investigated the relationships of WM volume as well as WM network architecture with ...
Inger Hellerhoff, Daniel Geisler, Fabio Bernardoni, Arne Doose, Friederike I. Tam, David M. Poitz, Nina Chotjewitz, Veit Roessner, Katja Akgün, Tjalf Ziemssen, Stefan Ehrlich   +10 more
wiley   +1 more source

Directionality of longitudinal associations between frontostriatal structural connectivity and depressive symptoms in adolescent girls

Journal of Child Psychology and Psychiatry, EarlyView.
Background Individual differences in the structure and function of the frontostriatal reward network have been related to depression. However, there is a strong need for prospective, longitudinal studies aiming to understand the role of frontostriatal networks in depression in a developmental context.
Marjolein E.A. Barendse, Chris J. Machle, Rogier Kievit, Jennifer H. Pfeifer   +3 more
wiley   +1 more source

Early-life maternal probiotic supplementation programs sex- and region-specific gene expression in the adult offspring brain. [PDF]

Brain Behav Immun Health
Siegler Lathrop T, Martínez Sanchez I, Chronakis IS, Diaz Heijtz R.   +3 more
europepmc   +1 more source

Chronic silencing of subsets of cortical layer 5 pyramidal neurons has a long‐term influence on the laminar distribution of parvalbumin interneurons and the perineuronal nets

Journal of Anatomy, Volume 246, Issue 4, Page 479-504, April 2025.
Chronic silencing of subsets of layer 5 projection neurons has distinct effects on the laminar distribution of PV interneurons and the perineuronal nets in the adult primary motor and somatosensory cortex. Abstract Neural networks are established throughout cortical development, which require the right ratios of glutamatergic and GABAergic neurons ...
Florina P. Szabó, Veronika Sigutova, Anna M. Schneider, Anna Hoerder‐Suabedissen, Zoltán Molnár   +4 more
wiley   +1 more source