Results 141 to 150 of about 43,839 (265)
Cholinergic and Glutamatergic Axons Differentially Require Glial Support in the Drosophila PNS
In the Drosophila PNS, motor‐ and sensory axons (magenta, green) differentially interact with wrapping glial processes. Sensory axons are more weakly associated with wrapping glia and show a length‐dependent degeneration upon loss of wrapping glia.
Steffen Kautzmann+3 more
wiley +1 more source
Do Action Potentials Regulate Myelination? [PDF]
Bernard Zalc, R. Douglas Fields
openalex +1 more source
Ablation of autophagy in oligodendrocytes reveals increased PLP expression, myelin abnormalities, axon degeneration, and increased microglia activation in aged mice. The aged mice exhibit marked deficits in learning and memory tasks. ABSTRACT The aging central nervous system (CNS) is often marked by myelin degeneration, yet the underlying mechanisms ...
Niki Ktena+8 more
wiley +1 more source
Dysregulation of NAD+ metabolism induces a Schwann cell dedifferentiation program [PDF]
The Schwann cell (SC) is the major component of the peripheral nervous system (PNS) that provides metabolic and functional support for peripheral axons. The emerging roles of SC mitochondrial function for PNS development and axonal stability indicate the
Hackett, Amber R+4 more
core +1 more source
A Dual Role Of Erbb2 In Myelination And In Expansion Of The Schwann Cell Precursor Pool [PDF]
Alistair N. Garratt+4 more
openalex +1 more source
Amyloid‐β peptide induces early oligodendrocyte differentiation and dorsal myelination in the zebrafish larvae spinal cord. Pan‐PKC inhibitor Gö6983 restores the aforementioned alterations in oligodendrocytes and myelin. ABSTRACT Soluble forms of amyloid‐β (Aβ) peptide have been proposed as candidates to induce oligodendrocyte (OL) and myelin ...
Uxue Balantzategi+7 more
wiley +1 more source
TGF beta type II receptor signaling controls Schwann cell death and proliferation in developing nerves [PDF]
During development, Schwann cell numbers are precisely adjusted to match the number of axons. It is essentially unknown which growth factors or receptors carry out this important control in vivo.
D'Antonio, M+6 more
core
Schwann Cell Myelination Requires Timely and Precise Targeting of P0 Protein [PDF]
Xiaoju Yin+5 more
openalex +1 more source
Zdhhc9 ablation grossly changes gene expression and myelin protein levels in CNS WM. Zdhhc9 is important for the establishment of mature oligodendrocyte subtypes. Zdhhc9 is important for axon myelination and the maintenance of myelin integrity. ABSTRACT Two percent of patients with X‐linked intellectual disability (XLID) exhibit loss‐of‐function ...
Rocio B. White+9 more
wiley +1 more source
Participants analyzed included 40 adults aged 18–20 and 40 children aged 6–8, who were cued with a sound that directed their attention to the location of an upcoming stimulus. The stimulus presented to the right or left of the participant in either the tactile, auditory or visual modalities and participants responded to the stimulus by pressing a foot ...
Staci Meredith Weiss, Peter J. Marshall
wiley +1 more source