Results 141 to 150 of about 43,839 (265)

Cholinergic and Glutamatergic Axons Differentially Require Glial Support in the Drosophila PNS

open access: yesGlia, EarlyView.
In the Drosophila PNS, motor‐ and sensory axons (magenta, green) differentially interact with wrapping glial processes. Sensory axons are more weakly associated with wrapping glia and show a length‐dependent degeneration upon loss of wrapping glia.
Steffen Kautzmann   +3 more
wiley   +1 more source

Do Action Potentials Regulate Myelination? [PDF]

open access: green, 2000
Bernard Zalc, R. Douglas Fields
openalex   +1 more source

Disruption of Oligodendroglial Autophagy Leads to Myelin Morphological Deficits, Neuronal Apoptosis, and Cognitive Decline in Aged Mice

open access: yesGlia, EarlyView.
Ablation of autophagy in oligodendrocytes reveals increased PLP expression, myelin abnormalities, axon degeneration, and increased microglia activation in aged mice. The aged mice exhibit marked deficits in learning and memory tasks. ABSTRACT The aging central nervous system (CNS) is often marked by myelin degeneration, yet the underlying mechanisms ...
Niki Ktena   +8 more
wiley   +1 more source

Dysregulation of NAD+ metabolism induces a Schwann cell dedifferentiation program [PDF]

open access: yes, 2018
The Schwann cell (SC) is the major component of the peripheral nervous system (PNS) that provides metabolic and functional support for peripheral axons. The emerging roles of SC mitochondrial function for PNS development and axonal stability indicate the
Hackett, Amber R   +4 more
core   +1 more source

A Dual Role Of Erbb2 In Myelination And In Expansion Of The Schwann Cell Precursor Pool [PDF]

open access: green, 2000
Alistair N. Garratt   +4 more
openalex   +1 more source

Amyloid‐β Dysregulates Oligodendroglial Lineage Cell Dynamics and Myelination via PKC in the Zebrafish Spinal Cord

open access: yesGlia, EarlyView.
Amyloid‐β peptide induces early oligodendrocyte differentiation and dorsal myelination in the zebrafish larvae spinal cord. Pan‐PKC inhibitor Gö6983 restores the aforementioned alterations in oligodendrocytes and myelin. ABSTRACT Soluble forms of amyloid‐β (Aβ) peptide have been proposed as candidates to induce oligodendrocyte (OL) and myelin ...
Uxue Balantzategi   +7 more
wiley   +1 more source

TGF beta type II receptor signaling controls Schwann cell death and proliferation in developing nerves [PDF]

open access: yes, 2006
During development, Schwann cell numbers are precisely adjusted to match the number of axons. It is essentially unknown which growth factors or receptors carry out this important control in vivo.
D'Antonio, M   +6 more
core  

Schwann Cell Myelination Requires Timely and Precise Targeting of P0 Protein [PDF]

open access: bronze, 2000
Xiaoju Yin   +5 more
openalex   +1 more source

The X‐Linked Intellectual Disability Gene, ZDHHC9, Is Important for Oligodendrocyte Subtype Determination and Myelination

open access: yesGlia, EarlyView.
Zdhhc9 ablation grossly changes gene expression and myelin protein levels in CNS WM. Zdhhc9 is important for the establishment of mature oligodendrocyte subtypes. Zdhhc9 is important for axon myelination and the maintenance of myelin integrity. ABSTRACT Two percent of patients with X‐linked intellectual disability (XLID) exhibit loss‐of‐function ...
Rocio B. White   +9 more
wiley   +1 more source

Anticipation across modalities in children and adults: Relating anticipatory alpha rhythm lateralization, reaction time, and executive function

open access: yesDevelopmental Science, Volume 26, Issue 1, January 2023., 2023
Participants analyzed included 40 adults aged 18–20 and 40 children aged 6–8, who were cued with a sound that directed their attention to the location of an upcoming stimulus. The stimulus presented to the right or left of the participant in either the tactile, auditory or visual modalities and participants responded to the stimulus by pressing a foot ...
Staci Meredith Weiss, Peter J. Marshall
wiley   +1 more source

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