Results 181 to 190 of about 61,218 (243)

Human iPSC-derived neural progenitor cells rescue motor function and brain pathology in symptomatic Canavan disease mice. [PDF]

Stem Cell Reports
Jackson N, Feng L, Chao J, Ye P, Luong Q, Galo K, Sun G, Hu W, Shi Y.   +8 more
europepmc   +1 more source

Immunoaffinity‐Mimetic Assembly of Peptide‐Aptamer Conjugates and Stem Cell‐Derived Exosomes into Hierarchical Microgels for Spinal Cord Injury Repair

Advanced Science, Volume 13, Issue 16, 18 March 2026.
Inspired by antibody‐antigen binding, this study develops an unprecedented immunoaffinity‐mimetic assembly strategy, with Peptide‐AptCD63 conjugates acting as antibody surrogates binding CD63 epitopes on mesenchymal stem cell‐derived exosomes. This creates a hierarchical microstructure intended to synergistically integrate antioxidative and anti ...
Dantong Zheng, Yuxin Bai, Zhibo Liu, Zinan Zhao, Yiming Kong, Yao Xu, Qi Jia, Rongrong Zhu, Yong Hu   +8 more
wiley   +1 more source

Myoclonus in Pediatric Metabolic Diseases: Clinical Spectrum, Mechanisms, and Treatable Causes-A Systematic Review. [PDF]

Metabolites
Majewska E, Zdort Z, Ochocka A, Paprocka J.   +3 more
europepmc   +1 more source

Schwann Cell Synthesized Cholesterol Orchestrates Peripheral Nerve Regeneration via Structural and IGF1‐Dependent Signaling Mechanisms

Advanced Science, Volume 13, Issue 16, 18 March 2026.
This study reveals that Schwann cell FDFT1‐mediated cholesterol synthesis is essential for peripheral nerve regeneration via dual roles: as a structural component for myelin and as a metabolic signal that upregulates IGF1. IGF1 promotes axonal growth through paracrine action and enhances Schwann cell differentiation/ myelination via an intrinsic IGF1R ...
Shuyi Xu, Ye He, Ying Zou, Mengyao Zhao, Jiaqi Zhang, Yizhou Xu, Jiale Cai, Xiongbo Luo, Xinrui Ma, Saini Wu, Yuling Huang, Xianghai Wang, Jiasong Guo   +12 more
wiley   +1 more source

A metabolic switch for myelination. [PDF]

Cell Regen
Niu S, Zhao L, Jia D.
europepmc   +1 more source

Non‐RASopathy Genetic Syndromes Identified as the Molecular Cause of Disease in Patients Previously Diagnosed With Noonan Syndrome

American Journal of Medical Genetics Part A, Volume 200, Issue 3, Page 661-672, March 2026.
ABSTRACT Noonan Syndrome (NS) is a clinically and genetically heterogeneous condition characterized by typical facial dysmorphisms, short stature, congenital heart defects, and developmental delays. While variants in genes such as PTPN11, SOS1, and RAF1 account for most genetically confirmed cases, diagnosis is challenging due to phenotypic overlap ...
Gabriela Jeesoo Kim, Alexsandra Christianne Malaquias, Debora Romeo Bertola, Raissa Carneiro Rezende, Laurana De Polli Cellin, Lucas Vieira Lacerda Pires, Ana Maria Santillan‐Vasconez, Antônio Marcondes Lerario, Renata da Cunha Scalco, Alexander Augusto de Lima Jorge   +9 more
wiley   +1 more source

Specific Association Patterns Between Brain Glutathione Levels, Myelination, and Functional Connectivity in Adults With Autism Spectrum Disorder. [PDF]

Autism Res
Iwabuchi T, Hirai T, Umeda N, Yogo H, Nishimiya Y, Nishigaki Y, Watanabe M, Yamasue H, Tsujii M, Tsuchiya KJ, Matsuzaki H.   +10 more
europepmc   +1 more source

From cradle to cortex: An exposome‐ and equity‐centered perspective of neurocognitive aging and dementia risk in the era of climate change

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract The convergence of climate change, adverse environmental exposures, and rapid population aging necessitates an equity‐based paradigm shift in safeguarding brain health across the life course. Older adults, especially those in marginalized and low‐resource settings, face disproportionate exposure to air pollution, toxicants, and climate‐related
Kelly E. Perry, Jenna Merenstein
wiley   +1 more source

Dmdmdx mice have defective oligodendrogenesis, delayed myelin compaction and persistent hypomyelination

Disease Models & Mechanisms
Andrea J. Arreguin, Zijian Shao, Holly Colognato   +2 more
doaj   +1 more source

Human Myelin Spheres for in Vitro Oligodendrocyte Maturation, Myelination and Neurological Disease Modeling. [PDF]

Stem Cell Rev Rep
Ahuja K, Ramezankhani R, Wang X, Burg T, Amos G, Neyrinck K, Silva A, Arekatla G, Cassidy EE, Nami F, Terryn J, Wierda K, Vints K, Vandamme N, Poovathingal S, Lambrichts I, Swinnen JV, Van Den Bosch L, De Groef L, Moons L, Verfaillie C, Neyts J, Jochmans D, Chai YC.   +23 more
europepmc   +1 more source