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Acute myeloid leukemia [PDF]

Methods in Molecular Biology, 2018
Advances in our understanding of the pathophysiology of acute myeloid leukemia (AML) have not yet led to major improvements in disease-free and overall survival of adults with this disease.
G. Ossenkoppele
semanticscholar   +3 more sources

Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards [PDF]

Nature Communications, 2016
Myeloid-derived suppressor cells (MDSC) are a heterogeneous population expanded in cancer and other chronic inflammatory conditions. Here the authors identify the challenges and propose a set of minimal reporting guidelines for mouse and human MDSC ...
V. Bronte, S. Brandau, Shu-Hsia Chen, M. Colombo, A. Frey, T. Greten, S. Mandruzzato, P. Murray, A. Ochoa, S. Ostrand-Rosenberg, P. Rodriguez, A. Sica, V. Umansky, R. Vonderheide, D. Gabrilovich   +14 more
semanticscholar   +4 more sources

Single-cell mutation analysis of clonal evolution in myeloid malignancies

Nature, 2020
Myeloid malignancies, including acute myeloid leukaemia (AML), arise from the expansion of haematopoietic stem and progenitor cells that acquire somatic mutations.
Benjamin Demaree, Linde A Miles, Robert L Bowman   +2 more
exaly   +2 more sources

Restoring metabolism of myeloid cells reverses cognitive decline in ageing

Nature, 2021
Congcong Wang, Miles H Linde, Amit U Joshi   +2 more
exaly   +2 more sources

Coordinated regulation of myeloid cells by tumours

Nature Reviews Immunology, 2012
Dmitry I Gabrilovich, Suzanne Ostrand-rosenberg, Vincenzo Bronte   +2 more
exaly   +2 more sources

Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer

Cell, 2020
Lei Zhang, Ziyi Li, Wei Zhang
exaly   +2 more sources

The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms

Leukemia, 2022
The upcoming 5th edition of the World Health Organization (WHO) Classification of Haematolymphoid Tumours is part of an effort to hierarchically catalogue human cancers arising in various organ systems within a single relational database.
J. Khoury, E. Solary, O. Abla, Yassmine M N Akkari, R. Alaggio, J. Apperley, R. Bejar, E. Berti, L. Busque, J. C. Chan, Weina Chen, Xinfa Chen, W. Chng, J. Choi, I. Colmenero, S. Coupland, N. Cross, D. de Jong, M. Elghetany, Emiko Takahashi, J. Emile, J. Ferry, L. Fogelstrand, M. Fontenay, U. Germing, S. Gujral, T. Haferlach, C. Harrison, Jennelle C Hodge, Shimin Hu, J. Jansen, R. Kanagal-Shamanna, H. Kantarjian, C. Kratz, Xiao-Qiu Li, M. Lim, K. Loeb, S. Loghavi, Andrea N Marcogliese, S. Meshinchi, P. Michaels, K. Naresh, Y. Natkunam, R. Nejati, G. Ott, E. Padron, K. Patel, N. Patkar, J. Picarsic, U. Platzbecker, Irene Roberts, Anna Schuh, W. Sewell, R. Siebert, P. Tembhare, J. Tyner, S. Verstovsek, Wei Wang, Brent Wood, W. Xiao, Cecilia C S Yeung, A. Hochhaus   +61 more
semanticscholar   +1 more source

International Consensus Classification of Myeloid Neoplasms and Acute Leukemia: Integrating Morphological, Clinical, and Genomic Data.

Blood, 2022
The classification of myeloid neoplasms and acute leukemias was last updated in 2016 within a collaboration between the World Health Organization (WHO), the Society for Hematopathology, and the European Association for Haematopathology.
D. Arber, A. Orazi, R. Hasserjian, M. Borowitz, K. Calvo, H. Kvasnicka, Sa A. Wang, A. Bagg, T. Barbui, S. Branford, C. Bueso-Ramos, J. Cortes, P. Dal Cin, C. Dinardo, H. Dombret, E. Duncavage, B. Ebert, E. Estey, F. Facchetti, K. Foucar, N. Gangat, U. Gianelli, L. Godley, N. Goekbuget, J. Gotlib, E. Hellström-Lindberg, G. Hobbs, R. Hoffman, E. Jabbour, J. Kiladjian, R. Larson, M. L. Le Beau, M. Loh, B. Löwenberg, E. Macintyre, L. Malcovati, C. Mullighan, C. Niemeyer, O. Odenike, S. Ogawa, A. Órfão, E. Papaemmanuil, F. Passamonti, K. Porkka, C. Pui, J. Radich, A. Reiter, M. Rozman, M. Rudelius, M. Savona, C. Schiffer, Annette Schmitt-Graeff, A. Shimamura, J. Sierra, W. Stock, R. Stone, M. Tallman, J. Thiele, H. Tien, A. Tzankov, A. Vannucchi, P. Vyas, A. Wei, O. Weinberg, A. Wierzbowska, M. Cazzola, H. Döhner, A. Tefferi   +67 more
semanticscholar   +1 more source

Concurrent Evaluation of the Expression and Methylation of Secreted Frizzled-Related Protein 2 along with Beta-Catenin Expression in Patients with non-M3 Acute Myeloid Leukemia [PDF]

Iranian Journal of Medical Sciences, 2021
Background: Wnt signaling is a critical pathway for the development of acute myeloid leukemia (AML). Some studies have evaluated the expression or methylation of secreted frizzled-related protein 2 (SFRP2) as an antagonist and beta-catenin (β-catenin) as
Fatemeh Mirzaeyan, Bahram Chahardouli, Amin Mirzaeian, Nasrin Alizad Ghandforoush, Kamran Alimoghaddam, Shahrbano Rostami   +5 more
doaj   +1 more source

Socioeconomic cost of AML in Sweden—A population‐based study using multiple nation‐wide registers

eJHaem, 2021
Acute myeloid leukemia (AML) is associated with a high economic and clinical burden. Recently novel therapies have been added to standard treatment regimens. Here, we evaluated the economic impact of AML up until the introduction of these novel therapies.
Emma Hernlund, Josefine Redig, Björn Paulsson, Åsa Rangert Derolf, Martin Höglund, Simona Vertuani, Gunnar Juliusson   +6 more
doaj   +1 more source