Results 1 to 10 of about 903,302 (304)

Single-cell mutation analysis of clonal evolution in myeloid malignancies

Nature, 2020
Myeloid malignancies, including acute myeloid leukaemia (AML), arise from the expansion of haematopoietic stem and progenitor cells that acquire somatic mutations.
Benjamin Demaree, Linde A Miles, Robert L Bowman   +2 more
exaly   +2 more sources

Coordinated regulation of myeloid cells by tumours

Nature Reviews Immunology, 2012
Dmitry I Gabrilovich, Suzanne Ostrand-rosenberg, Vincenzo Bronte   +2 more
exaly   +2 more sources

A pan-cancer single-cell transcriptional atlas of tumor infiltrating myeloid cells

Cell, 2021
Ziyi Li, Sijin Cheng, Ranran Gao
exaly   +2 more sources

Restoring metabolism of myeloid cells reverses cognitive decline in ageing

Nature, 2021
Congcong Wang, Miles H Linde, Amit U Joshi   +2 more
exaly   +2 more sources

Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer

Cell, 2020
Lei Zhang, Ziyi Li, Wei Zhang
exaly   +2 more sources

The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms

Leukemia, 2022
The upcoming 5th edition of the World Health Organization (WHO) Classification of Haematolymphoid Tumours is part of an effort to hierarchically catalogue human cancers arising in various organ systems within a single relational database.
J. Khoury, E. Solary, O. Abla, Yassmine M N Akkari, R. Alaggio, J. Apperley, R. Bejar, E. Berti, L. Busque, J. C. Chan, Weina Chen, Xinfa Chen, W. Chng, J. Choi, I. Colmenero, S. Coupland, N. Cross, D. de Jong, M. Elghetany, Emiko Takahashi, J. Emile, J. Ferry, L. Fogelstrand, M. Fontenay, U. Germing, S. Gujral, T. Haferlach, C. Harrison, Jennelle C Hodge, Shimin Hu, J. Jansen, R. Kanagal-Shamanna, H. Kantarjian, C. Kratz, Xiao-Qiu Li, M. Lim, K. Loeb, S. Loghavi, Andrea N Marcogliese, S. Meshinchi, P. Michaels, K. Naresh, Y. Natkunam, Reza Nejati, G. Ott, E. Padron, K. Patel, N. Patkar, J. Picarsic, U. Platzbecker, Irene Roberts, Anna Schuh, W. Sewell, R. Siebert, P. Tembhare, J. Tyner, S. Verstovsek, Wei Wang, Brent Wood, W. Xiao, Cecilia C S Yeung, A. Hochhaus   +61 more
semanticscholar   +1 more source

International Consensus Classification of Myeloid Neoplasms and Acute Leukemia: Integrating Morphological, Clinical, and Genomic Data.

Blood, 2022
The classification of myeloid neoplasms and acute leukemias was last updated in 2016 within a collaboration between the World Health Organization (WHO), the Society for Hematopathology, and the European Association for Haematopathology.
D. Arber, A. Orazi, R. Hasserjian, M. Borowitz, K. Calvo, H. Kvasnicka, Sa A. Wang, A. Bagg, T. Barbui, S. Branford, C. Bueso-Ramos, J. Cortes, P. Dal Cin, C. Dinardo, H. Dombret, E. Duncavage, B. Ebert, E. Estey, F. Facchetti, K. Foucar, N. Gangat, U. Gianelli, L. Godley, N. Goekbuget, J. Gotlib, E. Hellström-Lindberg, G. Hobbs, R. Hoffman, E. Jabbour, J. Kiladjian, R. Larson, M. L. Le Beau, M. Loh, B. Löwenberg, E. Macintyre, L. Malcovati, C. Mullighan, C. Niemeyer, O. Odenike, S. Ogawa, A. Órfão, E. Papaemmanuil, F. Passamonti, K. Porkka, C. Pui, J. Radich, A. Reiter, M. Rozman, M. Rudelius, M. Savona, C. Schiffer, Annette Schmitt-Graeff, A. Shimamura, J. Sierra, W. Stock, R. Stone, M. Tallman, J. Thiele, H. Tien, A. Tzankov, A. Vannucchi, P. Vyas, A. Wei, O. Weinberg, A. Wierzbowska, M. Cazzola, H. Döhner, A. Tefferi   +67 more
semanticscholar   +1 more source

Concurrent Evaluation of the Expression and Methylation of Secreted Frizzled-Related Protein 2 along with Beta-Catenin Expression in Patients with non-M3 Acute Myeloid Leukemia [PDF]

Iranian Journal of Medical Sciences, 2021
Background: Wnt signaling is a critical pathway for the development of acute myeloid leukemia (AML). Some studies have evaluated the expression or methylation of secreted frizzled-related protein 2 (SFRP2) as an antagonist and beta-catenin (β-catenin) as
Fatemeh Mirzaeyan, Bahram Chahardouli, Amin Mirzaeian, Nasrin Alizad Ghandforoush, Kamran Alimoghaddam, Shahrbano Rostami   +5 more
doaj   +1 more source

Socioeconomic cost of AML in Sweden—A population‐based study using multiple nation‐wide registers

eJHaem, 2021
Acute myeloid leukemia (AML) is associated with a high economic and clinical burden. Recently novel therapies have been added to standard treatment regimens. Here, we evaluated the economic impact of AML up until the introduction of these novel therapies.
Emma Hernlund, Josefine Redig, Björn Paulsson, Åsa Rangert Derolf, Martin Höglund, Simona Vertuani, Gunnar Juliusson   +6 more
doaj   +1 more source

The consequences of cohesin mutations in myeloid malignancies

Frontiers in Molecular Biosciences, 2023
Recurrent somatic mutations in the genes encoding the chromatin-regulatory cohesin complex and its modulators occur in a wide range of human malignancies including a high frequency in myeloid neoplasms. The cohesin complex has a ring-like structure which
Shubhra Ashish Bhattacharya, Shubhra Ashish Bhattacharya, Eve Dias, Eve Dias, Andrea Nieto-Aliseda, Marcus Buschbeck, Marcus Buschbeck   +6 more
doaj   +1 more source