Results 111 to 120 of about 47,761 (178)

MPRIP::PDGFRB fusion identified in a male patient with a myeloid/lymphoid neoplasm with eosinophilia. [PDF]

Ann Hematol
Gao M, Bachiashvili K, Jamy O, Harada S, Mackinnon AC, Ravindran A, Chen Y, Carroll AJ, Mikhail FM.   +8 more
europepmc   +1 more source

Targeting the Menin–KMT2A Axis in Acute Leukemia: From Epigenetic Dependency to Clinical Translation

European Journal of Haematology, Volume 117, Issue 1, Page 132-143, July 2026.
ABSTRACT Acute leukemias characterized by a shared epigenetic dependency on the menin–KMT2A axis rely on aberrant HOX‐driven transcriptional programs that sustain leukemic self‐renewal and impair differentiation. This dependency is most evident in KMT2A‐rearranged and NPM1‐mutated acute myeloid leukemia (AML), but also extends to other HOX‐dependent ...
Antonella Bruzzese, Ernesto Vigna, Enrica Antonia Martino, Santino Caserta, Francesco Mendicino, Maria Eugenia Alvaro, Caterina Labanca, Eugenio Lucia, Virginia Olivito, Mamdouh Skafi, Nicola Amodio, Fortunato Morabito, Massimo Gentile   +12 more
wiley   +1 more source

Case Report: Acute myeloid leukemia with mixed immunophenotypic features and TCF3::ZNF384 fusion in a pediatric patient with CNS involvement: a diagnostic and therapeutic challenge. [PDF]

Front Pediatr
Alonso-Carballo A, Mateos N, Gómez P, Montolio S, Salinas JA, Gutiérrez A, Sampol A, Martínez-Serra J.   +7 more
europepmc   +1 more source

Adult Erythroblastic Sarcoma With PCM1::JAK2 Fusion and a Novel NOP10::NUTM1 Fusion Complicated by Secondary HLH

Journal of Cellular and Molecular Medicine, Volume 30, Issue 14, July 2026.
ABSTRACT Erythroblastic sarcoma is a rare and aggressive hematologic malignancy presenting as a mass‐forming extramedullary proliferation of immature erythroid cells. Myeloid/lymphoid neoplasms with JAK2 rearrangement, most often PCM1::JAK2, may show eosinophilia, myelofibrosis, and expansion of immature erythroid precursors.
Tong Ge, Dong Kuang, Xia Mao, Songya Liu, Jin Wang, Qilin Ao, Min Xiao   +6 more
wiley   +1 more source

A Rare Case of Concurrent Chronic Lymphocytic Leukemia and Therapy-Unrelated Acute Myeloid Leukemia That Evolved From Myelodysplastic Neoplasm. [PDF]

Cureus
Bansil S, Lai SY, Lo AE, Dietz R, Reed JP.   +4 more
europepmc   +1 more source

Extranodal natural killer/T‐cell lymphoma: From fatal to curable

CA: A Cancer Journal for Clinicians, Volume 76, Issue 4, July/August 2026.
Abstract Extranodal natural killer (NK)/T‐cell lymphoma (ENKTCL) is one of the most aggressive non‐Hodgkin lymphomas characterized by NK‐cell or T‐cell origins, a geographic prevalence in Asian and South American populations, and Epstein–Barr virus (EBV) infection.
Jie Xiong, Yok‐Lam Kwong, Laurence de Leval, Shu‐Nan Qi, Choon Kiat Ong, Philippe Gaulard, Arnaud Jaccard, Steven M. Horwitz, Ye‐Xiong Li, Sai‐Juan Chen, Ritsuro Suzuki, Won Seog Kim, Wei‐Li Zhao   +12 more
wiley   +1 more source

Hypereosinophilia of persistent/unknown cause: a bone marrow-based study integrating WHO-HAEM5 criteria and myeloid next-generation sequencing. [PDF]

Am J Clin Pathol
Eletrebi MM, Sanchez-Ramirez J, Abdalla A, Holman CJ.   +3 more
europepmc   +1 more source

Genome‐wide association study in 21,271 individuals identifies 9 novel loci associated with circulating CD34+ hematopoietic stem and progenitor cell levels

HemaSphere, Volume 10, Issue 7, July 2026.
Yuwen Xie, Antton Lamarca, Caterina Cafaro, Gudmar Thorleifsson, Ludvig Ekdahl, Daniela Torres Di Bello, Zain Ali, Yen La, Lilja Stefansdottir, Alex Antill, Maroulio Pertesi, Maria Laura Mahecha Escobar, Magnús K. Magnússon, Simon N. Stacey, Kari Stefansson, Ingileif Jonsdottir, Göran Karlsson, Thorunn Olafsdottir, Unnur Thorsteinsdottir, Aitzkoa Lopez de Lapuente Portilla, Björn Nilsson   +20 more
wiley   +1 more source

Characterizing the impact of MLL fusion variants and fusion partners on leukemia plasticity using a human CRISPR-engineered MLL-rearranged leukemia model. [PDF]

Neoplasia
Radszuweit P, Fitzel R, Bruestl S, Hentrich T, Korkmaz F, Mankel B, González-Menéndez I, Rudat S, Marschalek R, Erkner E, Keppeler H, Schairer R, Luib L, Mezger M, Quintanilla-Martinez L, Schulze-Hentrich J, Lengerke C, Schneidawind D, Schneidawind C.   +18 more
europepmc   +1 more source

The Efficiency of Allotransplant in a Case of Acute Biphenotypic Myeloid and B-Lymphoid Leukemia (MPAL Myelo/B NOS) That Presented Concurrently with a Mediastinal Granulocytic Sarcoma Co-Expressing Lymphoid Markers Complicated by Cardiac Tamponade. [PDF]

Diagnostics (Basel)
Catana AC, Lazar Benedek E, Zaharie I, Mocanu L, Mera G, Popa C, Mondoc LM.   +6 more
europepmc   +1 more source