Results 181 to 190 of about 117,497 (280)

Decoding the Oncogenic Role of USP22 Through Pan‐Cancer Genomic and Epigenetic Analysis

Cancer Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background Ubiquitin‐specific protease 22, an important catalytic component of the human SAGA (Spt‐Ada‐GcN5 Acetyltransferase) complex, regulates the deubiquitination and methylation of histones, which in turn influences gene expression. Its overexpression alters gene regulation, transcription, cancer progression, and therapy resistance.
Uma Devi A., Prakash Kumar Shukla
wiley   +1 more source

A microRNA expression signature in infant t(4;11) KMT2A::AFF1+ BCP-ALL uncovers novel therapeutic targets. [PDF]

Hemasphere
Malouf C, Duguid A, Vrenken KS, Leah T, Medhi R, Camiolo G, Nitsche L, Jakobczyk H, Kotecha RS, Anderson RA, Barrett NA, Smith OP, Stam RW, Ottersbach K.   +13 more
europepmc   +1 more source

Identifying Donor Immune Cells in the Intestinal Mucosa of Chimeric Recipient Mice by Immunofluorescence

Current Protocols, Volume 6, Issue 5, May 2026.
Abstract Murine competitive congenic bone marrow transplantation is an important method used to identify genetic contributions to immune cell abundance, activation, differentiation, and mobilization, either in the bone marrow or in the peripheral organs of the host.
Vinicius Canale, Samuel Asiedu, Fuad Malki, Gang Chen, Meera G. Nair, Declan F. McCole   +5 more
wiley   +1 more source

Molecular Pathogenesis and Targeted Therapies for Myeloproliferative Hypereosinophilic Neoplasms. [PDF]

Curr Hematol Malig Rep
Hanna C, Rizkallah J, Charbel N, Sakkal S, Haddad FG.   +4 more
europepmc   +1 more source

Alteration Analysis of Bone Marrow Mesenchymal Stromal Cells from De Novo Acute Myeloid Leukemia Patients at Diagnosis

Stem Cells and Development, 2017
Laura Desbourdes, Joaquim Javary, Thomas Charbonnier, N. Ishac, J. Bourgeais, Aurore Iltis, J. Chomel, A. Turhan, F. Guilloton, K. Tarte, M. Demattei, Elfi Ducrocq, F. Rouleux-Bonnin, E. Gyan, O. Hérault, J. Domenech   +15 more
semanticscholar   +1 more source

Targeting the nuclear export receptor exportin‐1 in acute myeloid leukaemia: From biology to clinical translation

Clinical and Translational Medicine, Volume 16, Issue 5, May 2026.
• XPO1 hyperactivation promotes leukaemogenesis by altering nucleocytoplasmic transport and transcriptional control in acute myeloid leukaemia (AML). • Selinexor and eltanexor show preferential activity in NPM1‐mutated, DEK::NUP214‐positive and SF3B1‐mutated myeloid neoplasms.
Yifan Liu, Xiaoya Yun, Weidong Ding, Suxiao Li, Hui Liu   +4 more
wiley   +1 more source

Remethylation of Dnmt3a−/− hematopoietic cells is associated with partial correction of gene dysregulation and reduced myeloid skewing [PDF]

, 2020
Bangert, Celia V., Brune, Meryl K., Chang, Gue Su, Chen, David Y., Fronick, Catrina, Fulton, Robert S., George, Daniel R., Helton, Nichole M., Hoock, Mieke, Ketkar, Shamika, Leight, Elizabeth R., Ley, Timothy J., Miller, Christopher A., Petti, Allegra A., Ramakrishnan, Sai Mukund, Smith, Amanda M., Spencer, David H., Verdoni, Angela M.   +17 more
core   +1 more source

Dendritic cells in hematologic malignancies: a brief review of immunoregulation to new perspectives. [PDF]

Biochem Med (Zagreb)
de Almeida GB, Dos Santos MM, de Oliveira Barbosa D, Conceição RR, de Almeida Lopes B, de Melo Santos HH, Marchioro SB.   +6 more
europepmc   +1 more source

Constitutive expression of interleukin-8 and its receptor in human myeloid and lymphoid leukemia.

Blood, 1993
A. Tobler, B. Moser, B. Dewald, T. Geiser, H. Studer, M. Baggiolini, M. Fey   +6 more
semanticscholar   +1 more source

Dual‐Function Lipid‐Based Nanovector Strategy for Glioblastoma Immunotherapy: STING Activation and M1 Microglia Polarization

Drug Development Research, Volume 87, Issue 3, May 2026.
ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain malignancies because of its highly immunosuppressive tumor microenvironment and the limited penetration of therapeutics across the blood‐brain barrier (BBB). Although recent studies have separately explored STING agonism, microglial reprogramming, and nanocarrier‐based drug delivery, an ...
Mohamed S. Nafie, Mohamed Khaled Diab, Sherif Ashraf Fahmy   +2 more
wiley   +1 more source