Results 11 to 20 of about 523,497 (297)

Outcomes of allogeneic stem cell transplantation in acute leukemias – single centre study [PDF]

Documenta Haematologica, 2023
Aim: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is recommended in first complete remission (CR) for adverse and intermediate-risk acute myeloid leukemia (AML) and not recommended for AML patients with favourable disease.
Alexandra Oana ENACHE, Mihail MATEI, Lavinia Eugenia LIPAN, Oana Gabriela CRACIUN, Laura Diana STEFAN, Andra Georgiana STOICA, Zsofia VARADY, Alina Daniela TANASE   +7 more
doaj   +1 more source

Purification of Tumor-Associated Macrophages (TAM) and Tumor-Associated Dendritic Cells (TADC)

Bio-Protocol, 2014
Tumors are heterogeneous microenvironments where complex interactions take place between neoplastic cells and infiltrating inflammatory cells, such as tumor-associated macrophages (TAM) and tumor-associated dendritic cells (TADC).
Damya Laoui, Eva Overmeire, Jiri Keirsse, Kiavash Movahedi, Jo Ginderachter   +4 more
doaj   +1 more source

Understanding the glioblastoma immune microenvironment as basis for the development of new immunotherapeutic strategies

eLife, 2020
Cancer immunotherapy by immune checkpoint blockade has proven its great potential by saving the lives of a proportion of late stage patients with immunogenic tumor types.
Ana Rita Pombo Antunes, Isabelle Scheyltjens, Johnny Duerinck, Bart Neyns, Kiavash Movahedi, Jo A Van Ginderachter   +5 more
doaj   +1 more source

Survival and predictors of mortality among acute leukemia patients on follow‐up in Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia: A 5‐year retrospective cohort study

Cancer Reports, 2023
Background Although Ethiopia has more than 78% of leukemia cases and a significant burden of the disease, the survival of leukemia patients in the country is poorly recognized.
Bargude Balta, Tigistu Gebreyohannis, Erdaw Tachbele   +2 more
doaj   +1 more source

Philadelphia Chromosome-Positive de Novo AML or Blast Phase CML? Case Report and Short Literature Review [PDF]

Documenta Haematologica, 2023
The BCR::ABL1 translocation and the accompanying Philadelphia chromosome represents the first mutation which defined a disease, chronic myeloid leukemia.
Dan-Sebastian SOARE, Georgiana Elena ENE, Daniela DIACONESCU, Delia SOARE, Cristina ENACHE, Cristina MAMBET, Ion DUMITRU, Madalina CIRNU, Ana Maria VLADAREANU, Eugen RADU, Horia BUMBEA   +10 more
doaj   +1 more source

The tumour microenvironment harbours ontogenically distinct dendritic cell populations with opposing effects on tumour immunity

Nature Communications, 2016
Dendritic cells are antigen-presenting cells consisting of distinct subsets originating from different lineages. Here, the authors identify the subsets of dendritic cells populating the tumour tissue in both mice and humans and find they have opposing ...
Damya Laoui, Jiri Keirsse, Yannick Morias, Eva Van Overmeire, Xenia Geeraerts, Yvon Elkrim, Mate Kiss, Evangelia Bolli, Qods Lahmar, Dorine Sichien, Jens Serneels, Charlotte L. Scott, Louis Boon, Patrick De Baetselier, Massimiliano Mazzone, Martin Guilliams, Jo A. Van Ginderachter   +16 more
doaj   +1 more source

Murine Liver Myeloid Cell Isolation Protocol

Bio-Protocol, 2015
In homeostasis, the liver is critical for the metabolism of nutrients including sugars, lipids, proteins and iron, for the clearance of toxins, and to induce immune tolerance to gut-derived antigens.
Benoit Stijlemans, Amanda Sparkes, Chloé Abels, Jiri Keirsse, Lea Brys, Yvon Elkrim, Patrick Baetselier, Alain Beschin, Jo Ginderachter   +8 more
doaj   +1 more source

Macrophage Subsets in Obesity, Aligning the Liver and Adipose Tissue

Frontiers in Endocrinology, 2020
The increasing prevalence of obesity is accompanied by a rising incidence in metabolic syndrome and related pathologies such as non-alcoholic fatty liver disease. Macrophages are hypothesized to play central roles in these diseases, through their role as
Anneleen Remmerie, Anneleen Remmerie, Liesbet Martens, Liesbet Martens, Liesbet Martens, Charlotte L. Scott, Charlotte L. Scott   +6 more
doaj   +1 more source

Molecular Measurable Residual Disease Testing of Blood During AML Cytotoxic Therapy for Early Prediction of Clinical Response

Frontiers in Oncology, 2019
Measurable residual disease (MRD) testing after initial chemotherapy treatment can predict relapse and survival in acute myeloid leukemia (AML). However, it has not been established if repeat molecular or genetic testing during chemotherapy can offer ...
Hong Yuen Wong, Anthony D. Sung, Katherine E. Lindblad, Sheenu Sheela, Gregory W. Roloff, David Rizzieri, Meghali Goswami, Matthew P. Mulé, Nestor R. Ramos, Jingrong Tang, Julie Thompson, Christin B. DeStefano, Kristi Romero, Laura W. Dillon, Dong-Yun Kim, Catherine Lai, Christopher S. Hourigan   +16 more
doaj   +1 more source

Conservative Management of Presumed Fetal Anemia Secondary to Maternal Chemotherapy for Acute Myeloid Leukemia

American Journal of Perinatology Reports, 2021
Acute myeloid leukemia occurs rarely during pregnancy. When it is diagnosed remote from term, treatment in the form of daunorubicin plus cytarabine induction with consolidative cytarabine is typically undertaken after the first trimester. There is little
Christina M. Nowik, Alina S. Gerrie, Jonathan Wong   +2 more
doaj   +1 more source