Results 21 to 30 of about 523,497 (297)

Diamonds in the Rough: Harnessing Tumor-Associated Myeloid Cells for Cancer Therapy

Frontiers in Immunology, 2018
Therapeutic approaches that engage immune cells to treat cancer are becoming increasingly utilized in the clinics and demonstrated durable clinical benefit in several solid tumor types.
Emile J. Clappaert, Emile J. Clappaert, Aleksandar Murgaski, Aleksandar Murgaski, Helena Van Damme, Helena Van Damme, Mate Kiss, Mate Kiss, Damya Laoui, Damya Laoui   +9 more
doaj   +1 more source

Pancreatic Myeloid Sarcoma [PDF]

Cureus, 2020
Myeloid sarcoma is an isolated extramedullary tumor mass consisting of immature myeloid cells. It is characterized by highly variable outcomes and usually disrupts the normal architecture of the normal tissue in which it originates. It may occur de novo or be associated with other hematological malignancies.
Al-Obaidi, Ammar, Parker, Nathaniel A, Hussein Agha, Yasmine, Alqam, Hamzah, Page, Seth   +4 more
openaire   +2 more sources

Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells

Nature Communications, 2016
Tissue-resident macrophages are mostly derived from embryonic progenitors. Scott et al. develop a mouse model to specifically deplete Kupffer cells (KC) in vivoand show that monocyte-derived cells can repopulate KC niche and behave similar to their ...
Charlotte L. Scott, Fang Zheng, Patrick De Baetselier, Liesbet Martens, Yvan Saeys, Sofie De Prijck, Saskia Lippens, Chloé Abels, Steve Schoonooghe, Geert Raes, Nick Devoogdt, Bart N. Lambrecht, Alain Beschin, Martin Guilliams   +13 more
doaj   +1 more source

Adoptive Transfer of Monocytes Sorted from Bone Marrow

Bio-Protocol, 2019
Inflammatory Ly6Chi monocytes can give rise to distinct mononuclear myeloid cells in the tumor microenvironment, such as monocytic myeloid-derived suppressor cells (Mo-MDSC), immature macrophages, M2-like tumor-associated macrophages (TAMs), M1-like TAMs
Damya Laoui, Eva Overmeire, Chloé Abels, Jiri Keirsse, Jo Ginderachter   +4 more
doaj   +1 more source

Hematopoietic stem cells produce intermediate lineage adipocyte progenitors that simultaneously express both myeloid and mesenchymal lineage markers in adipose tissue

Adipocyte, 2021
Some adipocytes are produced from bone marrow hematopoietic stem cells. In vitro studies previously indicated that these bone marrow-derived adipocytes (BMDAs) were generated from adipose tissue macrophage (ATM) that lose their hematopoietic markers and ...
Kathleen M. Gavin, Timothy M. Sullivan, Joanne K. Maltzahn, Jeremy T. Rahkola, Alistair S. Acosta, Wendy M. Kohrt, Susan M. Majka, Dwight J. Klemm   +7 more
doaj   +1 more source

High-Yield Human Induced Pluripotent Stem Cell-Derived Monocytes and Macrophages Are Functionally Comparable With Primary Cells

Frontiers in Cell and Developmental Biology, 2021
Macrophages are pivotal effectors of host immunity and regulators of tissue homeostasis. Understanding of human macrophage biology has been hampered by the lack of reliable and scalable models for cellular and genetic studies.
Di Cui, Alexandra Franz, Sophie A. Fillon, Linda Jannetti, Timo Isambert, Katrin Fundel-Clemens, Heinrich J. Huber, Coralie Viollet, Alexander Ghanem, Akira Niwa, Bernd Weigle, Stefan Pflanz, Stefan Pflanz   +12 more
doaj   +1 more source

Acute myelogenous leukemia – current recommendations and approaches in molecular-genetic assessment

Romanian Journal of Internal Medicine, 2022
Acute myelogenous leukemia is a multi-step hematological malignancy, affecting function, growth, proliferation and cell cycle of myeloid precursors.
Yahya Dinnar, Hachmeriyan Mari, Micheva Ilina, Chervenkov Trifon   +3 more
doaj   +1 more source

Immunophenotypic Aberrancies in Acute Leukemia: A Tertiary Care Centre Experience

Oman Medical Journal, 2021
Objectives: Acute leukemias (AL) are a heterogeneous group of hematological malignancies with the presence of 20% or more blasts in the peripheral blood or bone marrow.
Monika Gupta, Lovekesh Monga, Dimple Mehrotra, Sonia Chhabra, Shivani Singhal, Rajeev Sen   +5 more
doaj   +1 more source

Age-related changes of the innate immune system of the palatine tonsil in a healthy cohort

Frontiers in Immunology, 2023
Although tonsillectomy is performed frequently, the role of palatine tonsils in life long immune protection or tolerance is still debated and the consequences of their removal for the immune system are of general interest.
Nico Andreas, Katharina Geißler, Juliane Priese, Orlando Guntinas-Lichius, Thomas Kamradt   +4 more
doaj   +1 more source

Acute myeloid leukaemia

Hematology, 2014
Acute myeloid leukaemia (AML) is a type of cancer of the part of the bone marrow that normally makes ‘myeloid’ cells.
Sandra, Hassan, Matthew, Smith
openaire   +2 more sources