Results 171 to 180 of about 749,314 (382)

Role of eIF4A1 in triple‐negative breast cancer stem‐like cell‐mediated drug resistance

open access: yesCancer Reports, Volume 5, Issue 12, December 2022., 2022
Abstract In cap‐dependent translation, the eukaryotic translation initiation factor 4A (eIF4A1) is an mRNA helicase is involved in unwinding of the secondary structure, such as the stem‐loops, at the 5′‐leader regions of the key oncogenic mRNAs. This facilitates ribosomal scanning and translation of the oncogenic mRNAs.
Dayanidhi Raman, Amit K. Tiwari
wiley   +1 more source

Radiosensitization of calreticulin‐overexpressing human glioma cell line by the polyphenolic acetate 7, 8‐diacetoxy‐4‐methylcoumarin

open access: yesCancer Reports, Volume 5, Issue 12, December 2022., 2022
Abstract Background Calreticulin (CRT), an endoplasmic reticulum–resident protein generally overexpressed in cancer cells, is associated with radiation resistance. CRT shows higher transacetylase activity, as shown by us earlier, in the presence of the polyphenolic acetates (like 7, 8‐diacetoxy‐4‐methylcoumarin, DAMC) and modifies the activity of a ...
Amit Verma   +6 more
wiley   +1 more source

Lipidomic approach for stratification of Acute Myeloid Leukemia patients [PDF]

open access: yesarXiv, 2016
The pathogenesis and progression of many tumors, including hematologic malignancies is highly dependent on enhanced lipogenesis. De novo fatty-acid synthesis permits accelerated proliferation of tumor cells by providing structural components to build the membranes.
arxiv  

Myasthenia Gravis in a Patient with Chronic Myeloid Leukemia Treated by Busulfan [PDF]

open access: bronze, 1968
M Djaldetti   +5 more
openalex   +1 more source

Involvement of the erythroid series in acute myeloid leukemia [PDF]

open access: bronze, 1979
Elke Beutler   +2 more
openalex   +1 more source

Self-Supervised Multiple Instance Learning for Acute Myeloid Leukemia Classification [PDF]

open access: yesarXiv
Automated disease diagnosis using medical image analysis relies on deep learning, often requiring large labeled datasets for supervised model training. Diseases like Acute Myeloid Leukemia (AML) pose challenges due to scarce and costly annotations on a single-cell level.
arxiv  

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