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Compound I of myeloperoxidase

Biochemical and Biophysical Research Communications, 1980
Summary The optical spectrum of the primary peroxide compound of myeloperoxidase (compound I) is reported. The spectrum, obtained in 1 msec after mixing native ferric myeloperoxidase with excess hydrogen peroxide, exhibits a Soret maximum at 425 nm (c = 52 mM−1 cm−1) and an increase in extinction of the ferric peroxidase at wavelengths higher than ...
J E, Harrison   +3 more
openaire   +2 more sources

Myeloperoxidase in Cardiovascular Disease

2013
Myeloperoxidase (MPO) plays a central role in the innate immune system by generating leukocyte-derived oxidants to combat invading pathogens. These reactive intermediates have been increasingly recognized to be potentially deleterious, causing oxidative injury in inflammatory disease states such as cardiovascular disease.
Robert A, Koeth   +2 more
openaire   +2 more sources

The development of myeloperoxidase inhibitors

Bioorganic & Medicinal Chemistry Letters, 2019
Myeloperoxidase (MPO), an abundant hemoprotein present in neutrophils and monocytes, plays a significant role in immune surveillance and host defense mechanisms. However, increased MPO activity has been linked to a number of pathologies with compelling evidence in initiation and progression of inflammatory events.
openaire   +2 more sources

Myeloperoxidase: Growing Importance in Cancer Pathogenesis and Potential Drug Target

Pharmacology & Therapeutics, 2022
Julia Kargl   +2 more
exaly  

MYELOPEROXIDASE*

Annals of the New York Academy of Sciences, 1958
openaire   +2 more sources

Myeloperoxidase

Analytical Biochemistry, 1968
Norman Felberg, Julius Schultz
openaire   +1 more source

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