Results 31 to 40 of about 32,127 (239)
Molecular pathogenesis of the myeloproliferative neoplasms [PDF]
Journal of Hematology & Oncology, 2021 AbstractThe Philadelphia negative myeloproliferative neoplasms (MPN) compromise a heterogeneous group of clonal myeloid stem cell disorders comprising polycythaemia vera, essential thrombocythaemia and primary myelofibrosis. Despite distinct clinical entities, these disorders are linked by morphological similarities and propensity to thrombotic ...
Graeme Greenfield +2 more
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Autoimmunity and the risk of myeloproliferative neoplasms
Haematologica, 2010 The causes of myeloproliferative neoplasm (MPN) are unknown. We conducted a large population-based study including 11,039 myeloproliferative neoplasm patients and 43,550 matched controls with the aim of assessing the associations between a personal ...
Sigurdur Y. Kristinsson +4 more
doaj +1 more source
Molecular approach to diagnose BCR/ABL negative chronic myeloproliferative neoplasms
Revista Brasileira de Hematologia e Hemoterapia, 2011 Chronic myeloproliferative neoplasms arise from clonal proliferation of hematopoietic stem cells. According to the World Health Organization myeloproliferative neoplasms are classified as: chronic myelogenous leukemia, polycythemia vera, essential ...
Michelle Maccarini Barcelos +1 more
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Frontiers in Oncology, 2020 Numerous studies have documented ultrastructural abnormalities in malignant megakaryocytes from bone marrow (BM) of myelofibrosis patients but the morphology of these cells in spleen, an important extramedullary site in this disease, was not investigated
Maria Zingariello +8 more
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Biomarker Research, 2021 Background Chronic myeloid leukemia (CML) and chronic neutrophilic leukemia (CNL) are two myeloproliferative neoplasms with mutually exclusive diagnostic criteria.
Sarah A. Carratt +4 more
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Update in the myeloproliferative neoplasms [PDF]
Clinical Medicine, 2014 The differential diagnosis of haematological abnormalities, such as leucocytosis, erythocytosis, thrombocytosis or indeed anaemia, is wide and disarming. Here we report on significant updates in the differential diagnosis of erythrocyosis and thrombocytosis presenting a simplified schema for the clinician.
Harrison, Claire N, McMullin, Mary F
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Acta Medica, 2010 Neutrophilic dermatosis of the dorsal hands is a variant of Sweet's syndrome. We herein describe an 83-year old woman with a neutrophilic dermatosis of the dorsal hands associated with a "myeloproliferative neoplasm, unclassifiable" and a simultaneous ...
Francisco José Fernández-Fernández +4 more
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Genetics of Myeloproliferative Neoplasms [PDF]
The Cancer Journal, 2014 In the last decade, genomic studies have identified multiple recurrent somatic mutations in myeloproliferative neoplasms (MPNs). Beginning with the discovery of the JAK2 V617F mutation, multiple additional mutations have been found that constitutively activate cell-signaling pathways, including MPL, CBL, and LNK.
Aaron D. Viny, Ross L. Levine
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Renal disease associated with myeloproliferative neoplasms and myelodysplastic syndrome/myeloproliferative neoplasms [PDF]
Histopathology, 2020 AimsRenal changes in patients with myeloproliferative neoplasms (MPNs) or myelodysplastic syndrome (MDS)/MPNs have been addressed by few, respectively no, reports. The aim of this study was to focus on a systematic evaluation of renal biopsies in patients with MPNs or MDS/MPNs.Methods and resultsThe cohort comprised 29 patients (23 men) aged 67 ± 11 ...
Maike Büttner‐Herold +3 more
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Morphology of myeloproliferative neoplasms
International Journal of Laboratory Hematology, 2023 AbstractMyeloproliferative neoplasms (MPN) are a group of clonal haematological malignancies first described by Dameshek in 1957. The Philadelphia‐negative MPN that will be described are polycythaemia vera (PV), essential thrombocythaemia (ET), pre‐fibrotic myelofibrosis and primary myelofibrosis (PMF).
Zi Yun Ng +3 more
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