Results 51 to 60 of about 49,427 (236)

Methylation of TET2, CBL and CEBPA in Ph-negative myeloproliferative neoplasms [PDF]

, 2010
A loss-of-function mutation of TET2, CBL and CEBPA has been implicated in the pathogenesis or leukaemic transformation of myeloproliferative neoplasm.
Chim, CS, Fung, TK, Wan, TS, Wong, KF
core   +1 more source

Progress against non-Hodgkin lymphoma in the Netherlands: Incidence, patterns of care and prognosis since 1989 (Studies with cancer registry data) [PDF]

, 2010
Cancers arising from the haematopoietic and lymphoid tissue comprise a heterogeneous group of malignancies with diverse clinical and biological features.
Schans, S.A.M. (Saskia) van de
core  

Estimating the prevalence of hematological malignancies and precursor conditions using data from Haematological Malignancy Research Network (HMRN) [PDF]

, 2016
Objective: Well-established cancer registries that routinely link to death registrations can estimate prevalence directly by counting patients alive at a particular point in time (observed prevalence).
Crouch, Simon, Li, Jinlei, Oliver, Steven Edward, Roman, Eve, Smith, Alexandra Gwen   +4 more
core   +1 more source

Ruxolitinib in the treatment of polycythemia vera: patient selection and special considerations. [PDF]

, 2016
The discovery of JAK2 V617F mutation in the mid-2000s started to fill the gap between clinical presentation of polycythemia vera (PV), first described by Vaquez at the end of the 19th century, and spontaneous erythroid colony formation, reported by ...
Alberio, L., Blum, S., Martins, F.
core   +2 more sources

Differential Diagnoses of Systemic Mastocytosis in Routinely Processed Bone Marrow Biopsy Specimens: A Review [PDF]

, 2010
Diagnosis of systemic mastocytosis (SM) is mainly based on the morphological demonstration of compact mast cell infiltrates in various tissue sites. In almost all patients such infiltrates are detected in the bone marrow.
Horny, H. -P., Sotlar, K., Valent, P.
core   +1 more source

772 MHC-I skewing in mutant calreticulin-positive myeloproliferative neoplasms is countered by heteroclitic peptide cancer vaccination [PDF]

, 2021
Mathieu Gigoux, Roberta Zappasodi, Joseph Park, Cansu Cimen Bozkus, Levi Mangarin, David Redmond, Svena Verma, Sara Schad, Mariam M. George, Divya Venkatesh, Arnab Ghosh, Zaki Molvi, Baransel Kamaz, Anna E. Marneth, William S. Duke, Matthew Leventhal, Max Jan, Vincent T. Ho, Gabriela Hobbs, Trine Alma Knudsen, Vibe Skov, Lasse Kjær, Thomas Stauffer Larsen, Dennis Lund Hansen, R. Coleman Lindsley, Hans Carl Hasselbalch, Jacob Handlos Grauslund, Mads Hald Andersen, Morten Orebo Holmström, Timothy A. Chan, Raajit K. Rampal, Omar Abdel‐Wahab, Nina Bhardwaj, Ann Mullally, Jedd D. Wolchok, Taha Merghoub   +35 more
openalex   +1 more source

Újdonságok, aktualitások a polycythaemia vera diagnosztikájában és kezelésében | Diagnosis and treatment of polycythaemia vera: state of the art [PDF]

, 2016
Absztrakt A polycythaemia vera a Philadelphia-negatív krónikus myeloid neoplasiák közé tartozó ritka neoplasia, amelyre az emelkedett vörösvérsejttömeg okozta hiperviszkozitás a jellemző.
Borbényi, Zita, Marton, Imelda, Simon, Zsófia   +2 more
core   +1 more source

Mutation and Lineage Analysis of DNMT3A in BCR-ABL1-negative Chronic Myeloproliferative Neoplasms

International Journal of Gerontology, 2013
In addition to the JAK2 V617F mutation, somatic mutation in DNMT3A has been described in BCL-ABL1-negative myeloproliferative neoplasms (MPNs).
Huan-Chau Lin, Shu-Ching Wang, Caleb Gon-Shen Chen, Ming-Chih Chang, Wei-Ting Wang, Nai-Wen Su, Hung-I Cheng, Johnson Lin, Yi-Fang Chang, Ruey-Kuen Hsieh, Chien-Chung Chang, Yuchi Hwang, Ken-Hong Lim, Yuan-Yeh Kuo   +13 more
doaj   +1 more source

A data-driven network model of primary myelofibrosis: transcriptional and post-transcriptional alterations in CD34+ cells [PDF]

, 2016
microRNAs (miRNAs) are relevant in the pathogenesis of primary myelofibrosis (PMF) but our understanding is limited to specific target genes and the overall systemic scenario islacking.
Associazione italiana per la ricerca sul cancro Gruppo Italiano Malattie Mieloproliferative Investigators, Bisognin, A., BORTOLUZZI, STEFANIA, Calura, E., Coppe, A., Fanelli, T., Gaffo, E., Guglielmelli, P., MANFREDINI, Rossella, Mannarelli, C., NORFO, RUGGIERO, PENNUCCI, VALENTINA, Pizzini, S., Romualdi, C., Sales, G., Vannucchi, A. M., ZINI, Roberta   +16 more
core   +1 more source

Driver mutations (JAK2V617F, MPLW515L/K or CALR), pentraxin-3 and C-reactive protein in essential thrombocythemia and polycythemia vera

Journal of Hematology & Oncology, 2017
Background The driver mutations JAK2V617F, MPLW515L/K and CALR influence disease phenotype of myeloproliferative neoplasms (MPNs) and might sustain a condition of chronic inflammation.
Federico Lussana, Alessandra Carobbio, Silvia Salmoiraghi, Paola Guglielmelli, Alessandro Maria Vannucchi, Barbara Bottazzi, Roberto Leone, Alberto Mantovani, Tiziano Barbui, Alessandro Rambaldi   +9 more
doaj   +1 more source