Results 241 to 250 of about 41,135 (289)
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BioEssays, 2002
AbstractSomatic muscle formation is an unusual process as it requires the cells involved, the myoblasts, to relinquish their individual state and fuse with one another to form a syncitial muscle fiber. The potential use of myoblast fusion therapies to rebuild damaged muscles has generated continuing interest in elucidating the molecular basis of the ...
Heather A, Dworak, Helen, Sink
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AbstractSomatic muscle formation is an unusual process as it requires the cells involved, the myoblasts, to relinquish their individual state and fuse with one another to form a syncitial muscle fiber. The potential use of myoblast fusion therapies to rebuild damaged muscles has generated continuing interest in elucidating the molecular basis of the ...
Heather A, Dworak, Helen, Sink
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Formation of the Drosophila larval body wall muscles requires the specification, coordinated cellular behaviors and fusion of two cell types: Founder Cells (FCs) that control the identity of the individual muscle and Fusion Competent Myoblasts (FCMs ...
Mary K Baylies
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Yap regulates mitochondrial structural remodeling during myoblast differentiation
Yes-associated protein (Yap) is a core transcriptional coactivator in the downstream Hippo pathway that regulates cell proliferation and tissue growth. However, its role in the regulation of myoblast differentiation remains unclear.
Shiyuan Huang +2 more
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The kinetics of myoblast fusion
Experimental Cell Research, 1984The kinetics of myoblast fusion were estimated using two complementary assays. Both utilized suspensions of fusion-competent cells, i.e. 48-52-h cultures of chick pectoral muscle grown in a low-calcium medium, thus minimizing contributions arising from cellular migration.
N, Neff, C, Decker, A, Horwitz
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Chemotactic behavior of myoblasts
Developmental Biology, 1984Earlier studies have suggested that myogenic cells of somite origin migrate into the developing limb, but little is known about the factors affecting the pattern of migration. In order to understand the migratory behavior of myogenic cells, embryonic skeletal muscle cells were tested for their ability to migrate chemotactically using a modified Boyden ...
K, Venkatasubramanian, M, Solursh
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Repair of impaired myocardium by means of implantation of engineered autologous myoblast sheets
ObjectivesAutologous skeletal myoblast cell transplantation by means of the injection method is subject to the loss of intercellular communication, extracellular matrix, and cell numbers.
Yoshiki Sawa +2 more
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2008
Myogenic differentiation in Drosophila melanogaster, as in many other organisms, involves the generation of multinucleate muscle fibers through the fusion of myoblasts. Prior to fusion, the myoblasts become specified as one of two distinct cell types.
Susan M, Abmayr +2 more
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Myogenic differentiation in Drosophila melanogaster, as in many other organisms, involves the generation of multinucleate muscle fibers through the fusion of myoblasts. Prior to fusion, the myoblasts become specified as one of two distinct cell types.
Susan M, Abmayr +2 more
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Prostaglandins and myoblast fusion
Developmental Biology, 1977Physiological concentrations of prostaglandin E1 (10−7 and 10−10M) provoke a discrete burst of cell fusion in cultures of primary chick myoblasts, 5 hr after their addition but well before the start of fusion, under control conditions. Two inhibitors of prostaglandin synthesis, aspirin (2-acetoxybenzoic acid) and indomethacin (1-[p-chlorobenzoyl]-5 ...
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Experimental Cell Research, 1974
Abstract Attempts were made to reprogram chick erythrocyte nuclei to specify the synthesis of chick myosin. Chick erythrocytes were fused with rat myogenic cells with the aid of UV-inactivated Sendai virus. In the heterokaryons and hybrid myotubes which resulted from this fusion, the erythrocyte nuclei resumed RNA synthesis and formed nucleoli ...
S A, Carlsson +3 more
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Abstract Attempts were made to reprogram chick erythrocyte nuclei to specify the synthesis of chick myosin. Chick erythrocytes were fused with rat myogenic cells with the aid of UV-inactivated Sendai virus. In the heterokaryons and hybrid myotubes which resulted from this fusion, the erythrocyte nuclei resumed RNA synthesis and formed nucleoli ...
S A, Carlsson +3 more
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Utilization of myoblasts from transgenic mice to evaluate the efficacy of myoblast transplantation
Muscle & Nerve, 1994AbstractA possible treatment for Duchenne muscular dystrophy is the injection of normal myoblasts into dystrophic muscles to induce the formation of new, healthy, and dystrophin‐positive muscle fibers. To develop this therapy, it is important to identify the muscle fibers formed by the injected myoblasts in the host muscles.
I, Kinoshita, J, Huard, J P, Tremblay
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