Results 81 to 90 of about 41,135 (289)

The Paracrine Effect of Skeletal Myoblasts is Cardioprotective against Oxidative Stress and Involves EGFR-ErbB4 Signaling, Cystathionase, and the Unfolded Protein Response

Cell Transplantation, 2016
Therapeutic effects of skeletal myoblast transplantation into the myocardium are mediated via paracrine factors. We investigated the ability of myoblast-derived soluble mediators to protect cardiomyocytes from oxidative stress.
Antti Siltanen, Kristo Nuutila, Yukiko Imanishi, Hisazumi Uenaka, Johanna Mäkelä, Tommi Pätilä, Antti Vento, Shigeru Miyagawa, Yoshiki Sawa, Ari Harjula, Esko Kankuri   +10 more
doaj   +1 more source

MiRNA Profiling in Pectoral Muscle Throughout Pre- to Post-Natal Stages of Chicken Development

Frontiers in Genetics, 2020
MicroRNA (miRNA) is known to be an important regulator of muscle growth and development. The regulation of microRNA on the skeletal muscle phenotype of animals is mainly achieved by regulating the proliferation and differentiation of myoblasts.
Min Chen, Min Chen, Min Chen, Shaolan Zhang, Zhongxian Xu, Jian Gao, Shailendra Kumar Mishra, Qing Zhu, Xiaoling Zhao, Yan Wang, Huadong Yin, Xiaolan Fan, Bo Zeng, Mingyao Yang, Deying Yang, Qingyong Ni, Yan Li, Mingwang Zhang, Diyan Li   +18 more
doaj   +1 more source

Akirin1 promotes myoblast differentiation by modulating multiple myoblast differentiation factors

Bioscience Reports, 2019
Abstract Akirin1 is found to be involved in myoblast differentiation. However, the mechanism by which the Akirin1 gene regulates myoblast differentiation still remains unclear. In the present study, we found that ectopic expression of Akirin1 promoted myoblast differentiation by increasing the expression of myogenic regulatory factor ...
Wenqiang Sun, Shenqiang Hu, Jiwei Hu, Jiamin Qiu, Shuang Yang, Bo Hu, Xiang Gan, Hehe Liu, Liang Li, Jiwen Wang   +9 more
openaire   +2 more sources

CauFinder: Steering Cell‐State and Phenotype Transitions by Causal Disentanglement Learning

Advanced Science, EarlyView.
CauFinder combines causal disentanglement modeling and network control to prioritize causal drivers of cell‐state transitions from observational transcriptomic data. The framework separates transition‐relevant signals from spurious associations, nominates intervention targets across biological and disease contexts, and identifies DAAM1 as an actionable
Chengming Zhang, Zexi Chen, Yuanxiang Miao, Zuolin Shen, Deyu Cai, Shijie Tang, Yun Xue, Weifeng Guo, Hongbin Ji, Jian Liu, Kazuyuki Aihara, Luonan Chen   +11 more
wiley   +1 more source

Cell Therapy in Myology: Dynamics of Muscle Precursor Cell Death after Intramuscular Administration in Non-human Primates

Molecular Therapy: Methods & Clinical Development, 2017
Cell therapy could be useful for the treatment of myopathies. A problem observed in mice, with different results and interpretations, is a significant death among the transplanted cells.
Daniel Skuk, Jacques P. Tremblay
doaj   +1 more source

Biomarkers of Sarcopenia: Current Status and Future Perspectives

AGING MEDICINE, EarlyView.
In this review, we summarize the various biomarkers discovered in recent years, including biochemical, imaging, and physical testing markers. We analyze their advantages and disadvantages and propose potential ways to improve the diagnostic accuracy of biomarkers, as well as future research directions.
Bijin Luo, Wenhan Li, Yi Zhang, Mengchen Liu, Kemeng Zhang, Sui Huang, Ping He   +6 more
wiley   +1 more source

Cellular regulators of myoblast migration and myogenesis [PDF]

, 2012
Migration of myogenic cells is an important step in myogenesis and skeletal muscle repair. Migration is required for the cells to reach the site of damage, for their alignment and subsequent fusion.
Dimchev, Georgi Aleksandrov
core  

The Effect of Microfluidic Geometry on Myoblast Migration

, 2019
In vitro systems comprised of wells interconnected by microchannels have emerged as a platform for the study of cell migration or multicellular models.
Bryan J. Black, Vinit M. Sheth, Rahul Atmaramani, David W. Schmidtke, Alsmadi, Nesreen Zoghoul, David W. Schmidtke, Bryan J. Black, Pancrazio, Joseph J., Nesreen Zoghoul Alsmadi, Kevin H. Lam, Vinit M. Sheth, Kevin H. Lam, Joseph J. Pancrazio, Nesreen Zoghoul Alsmadi, Lam, Kevin H., Black, Brian J., Atmaramani, Rahul, Sheth, Vinit M., Joseph J. Pancrazio, Schmidtke, David W.   +19 more
core   +1 more source

Effect of flow stimulation on cultured myoblasts on micro-pattern

Nihon Kikai Gakkai ronbunshu, 2018
A parallel-piped flow channel with micro-striped patterns has been designed to study the effect of the shear field on the myoblast in vitro. The micro-pattern was manufactured with the photolithography technique and used for the scaffold of the cell ...
Haruka HINO, Hiromi SUGIMOTO, Yusuke SHINOZAKI, Yusuke TAKAHASHI, Shigehiro HASHIMOTO   +4 more
doaj   +1 more source

Bidirectional Myoblast-Pericyte Plasticity [PDF]

Developmental Cell, 2013
Microvascular pericytes are able to generate multiple mesenchymal cell types, including skeletal muscle myoblasts. Cappellari et al. (2013) report in this issue of Developmental Cell that myoblasts can return the favor by generating pericytes via the action of Dll4 Notch ligand and PDGF-BB.
openaire   +2 more sources