Results 251 to 260 of about 79,476 (305)

Myoblasts, Satellite Cells, and Myoblast Transfer

1990
The prospects for introducing “foreign” nuclei through the cell fusion process have been considered since it first became clear that skeletal muscle fibers form by fusion of many mononucleated myoblasts rather than the proliferation of skeletal muscle nuclei within fibers (Stockdale and Holtzer, 1961).
F E, Stockdale, E J, Hager, S E, Fernyak, J X, DiMario   +3 more
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Rapid death of injected myoblasts in myoblast transfer therapy

Muscle & Nerve, 1996
Myoblast transplantation has been proposed as a potential therapy for Duchenne muscular dystrophy (DMD). A Y-chromosome-specific probe was used to track the fate of donor male myoblasts injected into dystrophic muscles of female mdx mice (which are an animal model for DMD).
Y, Fan, M, Maley, M, Beilharz, M, Grounds   +3 more
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Myoblast differentiation in vitro: Morphological differentiation of mononucleated myoblasts

Developmental Biology, 1976
Abstract Phospholipase C from Clostridium perfringens has been shown previously to inhibit the fusion of cultured chick myoblasts without affecting recognition or cell cycle parameters. In this paper we report that the mononucleated myoblasts, in phospholipase C, synthesize thick and thin filaments and organize them into myofibrils, and that T ...
J A, Trotter, M, Nameroff
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Myoblast fusion in Drosophila

BioEssays, 2002
AbstractSomatic muscle formation is an unusual process as it requires the cells involved, the myoblasts, to relinquish their individual state and fuse with one another to form a syncitial muscle fiber. The potential use of myoblast fusion therapies to rebuild damaged muscles has generated continuing interest in elucidating the molecular basis of the ...
Heather A, Dworak, Helen, Sink
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The kinetics of myoblast fusion

Experimental Cell Research, 1984
The kinetics of myoblast fusion were estimated using two complementary assays. Both utilized suspensions of fusion-competent cells, i.e. 48-52-h cultures of chick pectoral muscle grown in a low-calcium medium, thus minimizing contributions arising from cellular migration.
N, Neff, C, Decker, A, Horwitz
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Chemotactic behavior of myoblasts

Developmental Biology, 1984
Earlier studies have suggested that myogenic cells of somite origin migrate into the developing limb, but little is known about the factors affecting the pattern of migration. In order to understand the migratory behavior of myogenic cells, embryonic skeletal muscle cells were tested for their ability to migrate chemotactically using a modified Boyden ...
K, Venkatasubramanian, M, Solursh
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Myoblast Fusion in Drosophila

2008
Myogenic differentiation in Drosophila melanogaster, as in many other organisms, involves the generation of multinucleate muscle fibers through the fusion of myoblasts. Prior to fusion, the myoblasts become specified as one of two distinct cell types.
Susan M, Abmayr, Shufei, Zhuang, Erika R, Geisbrecht   +2 more
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Prostaglandins and myoblast fusion

Developmental Biology, 1977
Physiological concentrations of prostaglandin E1 (10−7 and 10−10M) provoke a discrete burst of cell fusion in cultures of primary chick myoblasts, 5 hr after their addition but well before the start of fusion, under control conditions. Two inhibitors of prostaglandin synthesis, aspirin (2-acetoxybenzoic acid) and indomethacin (1-[p-chlorobenzoyl]-5 ...
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Phenotypic expression in chick erythrocyte X rat myoblast hybrids and in chick myoblast X rat myoblast hybrids

Experimental Cell Research, 1974
Abstract Attempts were made to reprogram chick erythrocyte nuclei to specify the synthesis of chick myosin. Chick erythrocytes were fused with rat myogenic cells with the aid of UV-inactivated Sendai virus. In the heterokaryons and hybrid myotubes which resulted from this fusion, the erythrocyte nuclei resumed RNA synthesis and formed nucleoli ...
S A, Carlsson, O, Luger, N R, Ringertz, R E, Savage   +3 more
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Utilization of myoblasts from transgenic mice to evaluate the efficacy of myoblast transplantation

Muscle & Nerve, 1994
AbstractA possible treatment for Duchenne muscular dystrophy is the injection of normal myoblasts into dystrophic muscles to induce the formation of new, healthy, and dystrophin‐positive muscle fibers. To develop this therapy, it is important to identify the muscle fibers formed by the injected myoblasts in the host muscles.
I, Kinoshita, J, Huard, J P, Tremblay
openaire   +2 more sources