Results 261 to 270 of about 78,749 (287)
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British Medical Bulletin, 1995
Recent identification of the genetic causes of several neuromuscular disorders has aroused interest in gene therapy in skeletal muscle. The genetic constitution of skeletal muscle can be altered by a number of means. Myoblasts can be used to introduce new genes, endogenous or exogenous, into muscle fibres during growth and repair.
T A, Partridge, K E, Davies
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Recent identification of the genetic causes of several neuromuscular disorders has aroused interest in gene therapy in skeletal muscle. The genetic constitution of skeletal muscle can be altered by a number of means. Myoblasts can be used to introduce new genes, endogenous or exogenous, into muscle fibres during growth and repair.
T A, Partridge, K E, Davies
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Chemotactic behavior of myoblasts
Developmental Biology, 1984Earlier studies have suggested that myogenic cells of somite origin migrate into the developing limb, but little is known about the factors affecting the pattern of migration. In order to understand the migratory behavior of myogenic cells, embryonic skeletal muscle cells were tested for their ability to migrate chemotactically using a modified Boyden ...
K, Venkatasubramanian, M, Solursh
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2008
Myogenic differentiation in Drosophila melanogaster, as in many other organisms, involves the generation of multinucleate muscle fibers through the fusion of myoblasts. Prior to fusion, the myoblasts become specified as one of two distinct cell types.
Susan M, Abmayr +2 more
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Myogenic differentiation in Drosophila melanogaster, as in many other organisms, involves the generation of multinucleate muscle fibers through the fusion of myoblasts. Prior to fusion, the myoblasts become specified as one of two distinct cell types.
Susan M, Abmayr +2 more
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Experimental Cell Research, 1974
Abstract Attempts were made to reprogram chick erythrocyte nuclei to specify the synthesis of chick myosin. Chick erythrocytes were fused with rat myogenic cells with the aid of UV-inactivated Sendai virus. In the heterokaryons and hybrid myotubes which resulted from this fusion, the erythrocyte nuclei resumed RNA synthesis and formed nucleoli ...
S A, Carlsson +3 more
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Abstract Attempts were made to reprogram chick erythrocyte nuclei to specify the synthesis of chick myosin. Chick erythrocytes were fused with rat myogenic cells with the aid of UV-inactivated Sendai virus. In the heterokaryons and hybrid myotubes which resulted from this fusion, the erythrocyte nuclei resumed RNA synthesis and formed nucleoli ...
S A, Carlsson +3 more
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Myoblast-Based Cell Transplantation
Heart Failure Reviews, 2003Cell transplantation is emerging as a new treatment designed tot improve the poor outcome of patients with cardiac failure. Its rationale is that implantation of contractile cells into postinfarction scars can functionally rejuvenate these areas. Primarily for practical reasons, autologous skeletal myoblasts have been the first to be tested clinically ...
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Prostaglandins and myoblast fusion
Developmental Biology, 1977Physiological concentrations of prostaglandin E1 (10−7 and 10−10M) provoke a discrete burst of cell fusion in cultures of primary chick myoblasts, 5 hr after their addition but well before the start of fusion, under control conditions. Two inhibitors of prostaglandin synthesis, aspirin (2-acetoxybenzoic acid) and indomethacin (1-[p-chlorobenzoyl]-5 ...
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1990
The work which forms the basis for my comments was done by the clinical evaluators in the CIDD group (1). I shall present only the conclusions, not the studies themselves.
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The work which forms the basis for my comments was done by the clinical evaluators in the CIDD group (1). I shall present only the conclusions, not the studies themselves.
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