Results 111 to 120 of about 218,133 (348)

Impact of Myocardial Fibrosis in Endurance Athletes: A Systematic Review

Heart Views
Regular physical exercise is undoubtedly associated with cardiovascular health benefit, increased longevity, and improved endurance performance. Competitive endurance athletes exceed the recommended exercise dose, which lead to pathologic cardiac ...
Rasha Kaddoura, Hassan Al-Tamimi
doaj   +1 more source

The significance of macrophage polarization subtypes for animal models of tissue fibrosis and human fibrotic diseases. [PDF]

, 2015
The systemic and organ-specific human fibrotic disorders collectively represent one of the most serious health problems world-wide causing a large proportion of the total world population mortality.
Ballater R, Beon M, Bryan N, Butterfield TA, Connolly MK, Desmoulière A, Fallowfield JA, Galván‐Peña S, Gordon S, Goumans M, Hu B, Ito T, Jimenez SA, Korns D, Krieg T, Lassen S, Lech M, Leibovich SJ, Lev B, Mantovani A, Mantovani A, Molumdar K, Nestle FO, O’Doherty U, Piera‐Velazquez S, Poland GA, Rafii R, Rigamonte E, Tacke F, Venbervliet B, Wang Y, Wick G, Wijesundera KK   +32 more
core   +2 more sources

A Photothermal Transducer Regulates Transmembrane Calcium Flow for Synergistic Osteoarthritis Therapy

Advanced Science, EarlyView.
Upon NIR irradiation at 808 nm, the activity of TRPV4 was inhibited by M2M@BPSC, which led to reduced calcium influx, mitochondrial protection, and, importantly, the transcriptional activation of the STAT6‐EGR2 pathway. The improved macrophage function indirectly readjusts the equilibrium between C‐ECM and F‐ECM to reconstruct a suitable ...
Chenqi Yu, Yang Liu, Kang Kang, Jianfeng Yu, Xiaowei Xia, Yaoge Deng, Yingjie Lu, Huilin Yang, Lisong Li, Wu Xu, Yijian Zhang, Xuesong Zhu   +11 more
wiley   +1 more source

Effect of Exogenous Adiponectin on Myocardial Fibrosis in Mice Models with Myocardial Fibrosis

Cardiology Plus, 2016
Background: Myocardial fibrosis is closely associated with cardiac dysfunction, arrhythmia, and sudden cardiac death. A model of myocardial fibrosis induced by isoprenaline was used to determine the influence of exogenous adiponectin on myocardial fibrosis. Materials and Methods: A total of 30 mice were equally and randomly divided into three groups as
Feng-Lin Jin, Qiang Xiao, Ke-Yang Ding, Jian Hou, Su-Mei Li, Xiu-Chang Li   +5 more
openaire   +2 more sources

MicroRNA-130a attenuates cardiac fibrosis after myocardial infarction through TGF-β/Smad signaling by directly targeting TGF-β receptor 1

, 2022
Yu Feng, Yintu Bao, Jiaxing Ding, Huili Li, Wei Liu, Xuehua Wang, Hongquan Guan, Zhijian J. Chen   +7 more
openalex   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

Deciphering myocardial fibrosis: a comprehensive bibliometric analysis of mechanism over the period 1992–2023

Journal of Cardiothoracic Surgery
Background Myocardial fibrosis is a critical link in preventing the progression of heart disease. This study conducted a bibliometric analysis of its mechanism to identify trends and hotspots, aiming to provide valuable references for heart disease ...
Jiaojiao Zhang, Wenhui Wang, Zhen Wang, Meiqi Zhou, Shengbing Wu   +4 more
doaj   +1 more source

The effect of pre-treatment with Troxerutin on myocardial fibrosis in rats with doxorubicin-induced cardiotoxicity [PDF]

مجله پزشکی دانشگاه علوم پزشکی تبریز
Background. Doxorubicin (DOX) is a highly effective anthracycline drug widely used in cancer treatment. Myocardial fibrosis, a key pathological consequence of DOX-induced cardiotoxicity, impairs cardiac function and increases the risk of heart failure ...
Babaei-Kouchaki - Sara, Badalzadeh Reza, Vahab Babapour, Panahi Negar, Ahmad Jamei Khosroshahi   +4 more
doaj   +1 more source

A biomarker guided approach in heart failure [PDF]

, 2014
Heart failure is one of the commonest diagnoses presenting to physicians in the community or hospital care. Symptoms are often subjective, with clinicians having to rely on clinical assessment and radiological imaging to manage these patients.
Abela, Mark
core  

Interleukin-18 mediates cardiac dysfunction induced by western diet independent of obesity and hyperglycemia in the mouse [PDF]

, 2017
Obesity and diabetes are independent risk factors for heart failure and are associated with the consumption of diet rich in saturated fat and sugar, Western diet (WD), known to induce cardiac dysfunction in the mouse through incompletely characterized ...
Abbate, A., Buzzetti, Raffaella, Carbone, Salvatore, Lee, P. J. H., Mauro, A. G., Mezzaroma, E., Toldo, S., Van Tassell, B.   +7 more
core   +2 more sources