Results 11 to 20 of about 218,133 (348)

Hypertensive myocardial fibrosis [PDF]

Nephrology Dialysis Transplantation, 2005
A variety of cardiac structural and functional changes, such as increased left ventricular mass (LVM), left atrial and aortic root enlargement, LV dysfunction, impairment of coronary reserve and prolonged ven- tricular repolarization, have been described in patients with long-standing arterial hypertension [1,2].
CUSPIDI, CESARE, Ciulla, M, Zanchetti, A.   +2 more
openaire   +5 more sources

A model based on clinical parameters to identify myocardial late gadolinium enhancement by magnetic resonance in patients with aortic stenosis: An observational study [PDF]

, 2020
Objective With increasing age, the prevalence of aortic stenosis grows exponentially, increasing left heart pressures and potentially leading to myocardial hypertrophy, myocardial fibrosis and adverse outcomes.
Alpendurada, Francisco, Dweck, Marc, Kuk, Mariya, Newsome, Simon, Pennell, Dudley J, Prasad, Sanjay K, Vassiliou, Vassilios S   +6 more
core   +1 more source

[Retracted] DDAH2 alleviates myocardial fibrosis in diabetic cardiomyopathy through activation of the DDAH/ADMA/NOS/NO pathway in rats. [PDF]

Int J Mol Med
Zhu ZD, Ye JM, Fu XM, Wang XC, Ye JY, Wu XR, Hua P, Liao YQ, Xuan W, Duan JL, Li WY, Fu H, Xia ZH, Zhang X.   +13 more
europepmc   +3 more sources

MicroRNA-325-3p Targets Human Epididymis Protein 4 to Relieve Right Ventricular Fibrosis in Rats with Pulmonary Arterial Hypertension

Cardiovascular Therapeutics, 2022
Background. Pulmonary arterial hypertension (PAH) usually causes right ventricular dysfunction, which is closely related to cardiac fibrosis. But cardiac fibrosis mechanism remains unclear.
Yi Tang, Xiaowei Huo, Junyu Liu, Yijin Tang, Min Zhang, Wenlin Xie, Zhaofen Zheng, Jin He, Jiayan Lian   +8 more
doaj   +1 more source

SARC Gene Mutation Is Associated With Myocardial Fibrosis Measured by Histopathology and Cardiac Magnetic Resonance in Patients With Hypertrophic Cardiomyopathy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Sarcomere gene mutation and myocardial fibrosis are both associated with poorer clinical outcomes in patients with hypertrophic cardiomyopathy (HCM).
Manyun Huang, Jian Zhang, Changpeng Song, Shuiyun Wang, Zhou Zhou, Hongyue Wang, Shihua Zhao, Kunlun Yin, Li Li, Shujuan Yang, Xinxin Zheng, Jie Lu, Xiaohong Huang   +12 more
doaj   +1 more source

Downregulation of lncRNA Miat contributes to the protective effect of electroacupuncture against myocardial fibrosis

Chinese Medicine, 2022
Background Myocardial fibrosis changes the structure of myocardium, leads to cardiac dysfunction and induces arrhythmia and cardiac ischemia, threatening patients’ lives.
Wenchuan Qi, Xiang Li, Yanrong Ren, Xueying Liu, Hongjuan Fu, Xiao Wang, Xiao Li, Jian Xiong, Qianhua Zheng, Dingjun Cai, Fanrong Liang   +10 more
doaj   +1 more source

Methyl Ferulic Acid Attenuates Human Cardiac Fibroblasts Differentiation and Myocardial Fibrosis by Suppressing pRB-E2F1/CCNE2 and RhoA/ROCK2 Pathway

Frontiers in Pharmacology, 2021
Background: Myocardial fibrosis is a key pathological process after myocardial infarction, which leads to poor outcomes in patients at the end stage. Effective treatments for improving prognosis of myocardial fibrosis are needed to be further developed ...
Rongheng Liao, Zhen Qi, Ri Tang, Renrong Wang, Yongyi Wang   +4 more
doaj   +1 more source

Diffuse Myocardial Fibrosis: Can We Reverse Course? [PDF]

JACC Basic Transl Sci
Spinale FG.
europepmc   +2 more sources

Impact of metabolic syndrome on cardiac function and myocardial fibrosis in hypertrophic obstructive cardiomyopathy following septal myectomy assessed by cardiac magnetic resonance. [PDF]

Quant Imaging Med Surg
Pan Z, Yang Z, Zhao Y, Wen J, Ran L, Tang D, Huang L, Xia L.   +7 more
europepmc   +2 more sources

Morphological and Functional Characteristics of Animal Models of Myocardial Fibrosis Induced by Pressure Overload

International Journal of Hypertension, 2020
Myocardial fibrosis is characterized by excessive deposition of myocardial interstitial collagen, abnormal distribution, and excessive proliferation of fibroblasts.
Yuejia Ding, Yuan Wang, Qiujin Jia, Xiaoling Wang, Yanmin Lu, Ao Zhang, Shichao Lv, Junping Zhang   +7 more
doaj   +1 more source