Results 31 to 40 of about 218,133 (348)

Multifunctional biomaterial platforms for blocking the fibrosis process and promoting cellular restoring effects in myocardial fibrosis therapy

Frontiers in Bioengineering and Biotechnology, 2022
Myocardial fibrosis is the result of abnormal healing after acute and chronic myocardial damage and is a direct cause of heart failure and cardiac insufficiency.
Tian Yue, Tian Yue, Shiqiang Xiong, Dezhi Zheng, Yi Wang, Pan Long, Jiali Yang, Jiali Yang, Dunzhu Danzeng, Han Gao, Xudong Wen, Xin Li, Jun Hou, Jun Hou   +13 more
doaj   +1 more source

Myocardial Fibrosis in the Pathogenesis, Diagnosis, and Treatment of Hypertrophic Cardiomyopathy

Cardiovascular Innovations and Applications, 2021
Hypertrophic cardiomyopathy (HCM) is a type of hereditary cardiomyopathy caused by gene mutation. Its histological features include cardiomyocyte hypertrophy and disarray as well as myocardial fibrosis.
Zeyi Cheng, Miaomiao Qi, Chengyuan Zhang, Yanxia Mao   +3 more
doaj   +1 more source

A review of the molecular mechanisms underlying the development and progression of cardiac remodeling [PDF]

, 2017
Pathological molecular mechanisms involved in myocardial remodeling contribute to alter the existing structure of the heart, leading to cardiac dysfunction.
Angelini, Francesco, Bordin, Antonella, Carrizzo, Albino, Chimenti, Isotta, DE FALCO, Elena, Forte, Maurizio, Frati, Giacomo, Nocella, Cristina, Pagano, Francesca, Palmerio, Silvia, Schiavon, Sonia, Schirone, Leonardo, Sciarretta, Sebastiano, Valenti, Valentina, Vecchione, Carmine, Yee, Derek   +15 more
core   +3 more sources

Comparison of T1 mapping techniques for ECV quantification. histological validation and reproducibility of ShMOLLI versus multibreath-hold T1 quantification equilibrium contrast CMR [PDF]

, 2012
BACKGROUND: Myocardial extracellular volume (ECV) is elevated in fibrosis or infiltration and can be quantified by measuring the haematocrit with pre and post contrast T1 at sufficient contrast equilibrium.
A. S. Flett, D. M. Sado, J. C. Moon, K. W. White, M. Fontana, MAESTRINI, VIVIANA, N. Roberts, S. K. Piechnik, S. M. Banypersad, S. Neubauer   +9 more
core   +1 more source

Biomarkers in patients with myocardial fibrosis

Open Life Sciences, 2017
Myocardial fibrosis is observed in many cardiovascular diseases including hypertension, heart failure and cardiomyopathy. Myocardial fibrosis has been proved to be reversible and treatable only under timely intervention, which makes early detection and ...
An Zhe, Yang Guang, Zheng Haikuo, Nie Wei, Liu Guohui   +4 more
doaj   +1 more source

DIAGNOSTIC METHODS FOR MYOCARDIAL FIBROSIS

Измерение, мониторинг, управление, контроль, 2023
Background. Myocardial fibrosis is a global public health problem because it is associated with almost all forms of cardiovascular diseases. Timely detection of myocardial fibrosis is an urgent task contributing to improving the quality of patients' life
Natalia A. Serzhantova
doaj   +1 more source

Lcz696 Alleviates Myocardial Fibrosis After Myocardial Infarction Through the sFRP-1/Wnt/β-Catenin Signaling Pathway

Frontiers in Pharmacology, 2021
Background: Lcz696 (ARNI, angiotensin receptor–neprilysin inhibitor; sacubitril/valsartan) shows an inhibitory effect on fibrosis after myocardial infarction (MI). However, the underlying signaling mechanisms are poorly understood.
Jing Liu, Jing Liu, Xuehui Zheng, Chen Zhang, Chunmei Zhang, Peili Bu   +5 more
doaj   +1 more source

Time spent with cats is never wasted: Lessons learned from feline acromegalic cardiomyopathy, a naturally occurring animal model of the human disease [PDF]

, 2018
BackgroundIn humans, acromegaly due to a pituitary somatotrophic adenoma is a recognized cause of increased left ventricular (LV) mass. Acromegalic cardiomyopathy is incompletely understood, and represents a major cause of morbidity and mortality.
A Colao, A Colao, A Colao, A Colao, A Colao, A Colao, A Colao, A Colao, A Mestron, A Piovesan, AC Dirtu, AM Pereira, B Posch, BJ Maron, BPP Meij, BR Bond, C Paige, C-Y Liu, CJL Little, CR Lamb, David B. Church, David J. Connolly, DJ Connolly, F Fracassi, G Jacobs, G Lombardi, G Lombardi, J Dal, J Gilbert, JA Myers, JK Sangster, JM Fletcher, JR Payne, JT Lie, Kieran Borgeat, LJ Wilkie, Lois Wilkie, M Galderisi, M Lesser, M Maxie Grant, M Nishiki, M Rosca, M-LL Jaffrain-Rea, MD Kittleson, ME Peterson, ME Peterson, NJ Pereira, Norelene Harrington, NS Moise, NS Moise, O Kershaw, OM Dekkers, P Menaut, PR Fox, PR Fox, PR Fox, PR Fox, PR Fox, R Baldelli, R Gostelow, R Pivonello, RC Weichselbaum, S Brown, S Fazio, S Fazio, S Fazio, S Fieffe, S Murarka, S Niessen, SJM Niessen, SJM Niessen, SJM Niessen, SK Liu, SK Liu, Stijn J. M. Niessen, SV Keyte, T Wagner, T. Rosol, Vincenzo Lionetti, Virginia Luis Fuentes, WL McGuffin   +80 more
core   +2 more sources

Biomarkers of Inflammation and Fibrosis in Kawasaki Disease Patients Years After Initial Presentation With Low Ejection Fraction. [PDF]

, 2020
Background Coronary artery aneurysms and myocarditis are well-recognized complications of Kawasaki disease (KD) but no systematic evaluation of the consequences of myocarditis has been performed in the subset presenting with low ejection fraction (EF ...
Burns, Jane C, He, Feng, Hoshino, Shinsuke, Jain, Sonia, Shimizu, Chisato, Tremoulet, Adriana H   +5 more
core  

Association Between Chronic Hepatitis C Virus Infection and Myocardial Infarction Among People Living With HIV in the United States. [PDF]

, 2019
Hepatitis C virus (HCV) infection is common among people living with human immunodeficiency virus (PLWH). Extrahepatic manifestations of HCV, including myocardial infarction (MI), are a topic of active research. MI is classified into types, predominantly
Budoff, Matt, Cachay, Edward R, Crane, Heidi M, Delaney, Joseph A, Geng, Elvin, Hawes, Stephen E, Heckbert, Susan R, Hunt, Peter W, Hurt, Christopher B, Kim, H Nina, Kitahata, Mari M, Lindström, Sara, Mathews, W Chris, Moore, Richard D, Mugavero, Michael J, Nance, Robin M, Peter, Inga, Saag, Michael S, Williams-Nguyen, Jessica   +18 more
core   +1 more source