Results 131 to 140 of about 60,797 (160)
Some of the next articles are maybe not open access.
Progress in Therapies for Myocardial Ischemia Reperfusion Injury
Current Drug Targets, 2017Experimental studies of acute myocardial infarction have revealed that up to half of the final infarct size may be due to reperfusion injury rather than the initial ischemic incident. Research over the past three decades has deepened our understanding of the molecular mechanisms underlying ischemic reperfusion injury and several therapeutic strategies ...
Hong-Jie, Chi +8 more
openaire +2 more sources
A Murine Model of Myocardial Ischemia–Reperfusion Injury
2018Ligation of the left anterior descending (LAD) coronary artery in the mouse heart is a widely used model to simulate myocardial infarction and ischemia-reperfusion injury. Here we describe a ligation technique routinely performed in our laboratory to induce myocardial infarction that may be used to study ischemia-reperfusion injury in the myocardium ...
Zhaobin, Xu +3 more
openaire +2 more sources
Antioxidants in the prevention of myocardial ischemia/reperfusion injury
Expert Review of Clinical Pharmacology, 2009In acute myocardial ischemia (AMI) the optimal treatment is rapid revascularization by angioplasty or pharmacological thrombolysis. While this is essential to resuscitate the ischemic myocardium, it results in further reperfusion injury and extension of the infarction.
Chengxue, Qin +2 more
openaire +2 more sources
Effects of tramadol on myocardial ischemia-reperfusion injury
Scandinavian Cardiovascular Journal, 2007The aim of the present study was to evaluate the effect of tramadol on isolated rat hearts subjected to global ischemia-reperfusion injury.Langerdorff perfused isolated rat hearts were subjected to 60 min of global ischemia following 60 min of reperfusion. In group I and III hearts were received tramadol before the onset of ischemia.
Bilir, Ayten +6 more
openaire +2 more sources
Calcium Antagonists and Experimental Myocardial Ischemia Reperfusion Injury
Journal of Cardiovascular Pharmacology, 1992A number of previous studies have reported that administration of calcium antagonists reduces acute ischemic injury in a variety of experimental models. More recently, however, it has been suggested that the beneficial effects of reperfusing the ischemic myocardium might be blunted by the paradoxical occurrence of a specific form of reperfusion ...
AMBROSIO, Giuseppe +2 more
openaire +3 more sources
Role of selectins in myocardial ischemia-reperfusion injury
The Annals of Thoracic Surgery, 1995During reperfusion of ischemic myocardium, there is a well-orchestrated interplay between the coronary vascular endothelium and the circulating neutrophils. This interplay involves the initial slowing or "rolling" of neutrophils along the endothelium during the early moments of reperfusion, followed by firm attachment and amplification of the ...
openaire +2 more sources
Statin and myocardial ischemia-reperfusion injury
International Journal of Cardiology, 2016Jun, Hu, Yao, Lu
openaire +2 more sources
Antioxidants and myocardial ischemia: reperfusion injuries.
Chang Gung medical journal, 2005Animal studies have demonstrated that restoration of blood flow to severely ischemic myocardium is a prerequisite for myocardial salvage. However, it has been shown that the restoration of blood flow to ischemic myocardium may be associated with deleterious changes of the myocardium, including arrhythmias, enzyme release, and contractile dysfunction ...
Jan-Kan, Chen, Shu-Er, Chow
openaire +1 more source