Results 241 to 250 of about 107,803 (293)

New Insights on Heat Shock Proteins as Regulators of Reactive Oxygen Species Across Various Stressors in Diseases

Cell Biochemistry and Function, Volume 44, Issue 2, February 2026.
ABSTRACT Living beings are persistently challenged by stress. Stress can be induced by internal stressors and external stressors. External stressors, including radiation, heat, heavy metals, nutritional imbalances, infections, and psychological stress, can induce protein denaturation, leading to misfolded or aggregated proteins.
Paka Sravan Kumar, Triveni Kodi, Adarsh Gopinathan, Bharath Harohalli Byregowda, Krishnadas Nandakumar, Anoop Kishore   +5 more
wiley   +1 more source

Heat Therapy: Targeting Health, Disease, and Disability

Comprehensive Physiology, Volume 16, Issue 1, February 2026.
The predominance of evidence suggests heat therapy has an impact on all aspects of health and performance, but the drivers of that improvement, the extent to which they are improved, and the specific populations in which improvements manifest are far from completely understood.
Rauchelle E. Richey, Robert D. Hyldahl, Brendan W. Kaiser, Paige C. Geiger, John R. Halliwill, Christopher T. Minson   +5 more
wiley   +1 more source

MAP3K3 Contributes to Myocardial Ischemia/Reperfusion Injury by Promoting Myeloid Cell Diapedesis through TAL1/JAM-A Pathway. [PDF]

Theranostics
Hu S, Zhang J, Wang J, Li C, Wang Y, Liang J, Huang R, Yang J, Gao Y, Qu Y, Yang H, Qian J, Tang W, Cao J, Zhang F, Ge J.   +15 more
europepmc   +1 more source

Inhaled Halogen‐Induced Oxidative Renal Damage and Dysfunction: A Lung Heart Kidney Axis

Comprehensive Physiology, Volume 16, Issue 1, February 2026.
Mechanisms of lung‐heart‐kidney interaction in inducing organ injury after chemical inhalation. Acute exposure to halogen gases causes extensive lung injury and acute cardiac damage leading to fatalities. Formation of highly reactive halogenated molecules in the pulmonary bed and their circulation resulting in oxidative stress and inflammation was ...
Juan Xavier Masjoan Juncos, Ahmed Zaky, Wesam Nasser, Amber J. Johns, Iram Zafar, Gajanan R. Jadhav, Jeremy B. Foote, Aftab Ahmad, Anupam Agarwal, Shama Ahmad   +9 more
wiley   +1 more source

Mitophagy: a novel avenue for herbal medicines alleviating myocardial ischemia/reperfusion injury. [PDF]

Apoptosis
Liao M, Men L, Gong M, Li Y, Wang Y, Xu D, Luan J, Zhou H, Liu M, Chen M.   +9 more
europepmc   +1 more source

ATGL From iWAT and BAT Is Crucial for Cardiac Remodeling and Metabolism After Myocardial Ischemia/Reperfusion

Comprehensive Physiology, Volume 16, Issue 1, February 2026.
Cardiac I/R activates adipose tissue. iatATGL‐KO increases adipocyte size and reduces lipogenesis in WAT, induces whitening and inflammation in BAT, and reduces circulating NEFA and adiponectin levels. As a consequence, cardiac function is reduced, scar formation enhanced, and remote myocardium shows elevated mechanical stress and oxygen consumption ...
Heba Zabri, Alisa Ucar, Luzhou Wang, Simone Gorressen, Richard Kretschmer, Daniel Gorski, Tobias Lautwein, Mirela Balan, Stefan Lehr, Andre Heinen, Axel Gödecke, Jens W. Fischer, Katharina Bottermann   +12 more
wiley   +1 more source

Maresin 1 alleviates myocardial ischemia-reperfusion injury in rats by suppressing inflammation. [PDF]

Eur J Histochem
Xiao H, Liu J, Cai Q, Liang S, Hu Z, Chen X.   +5 more
europepmc   +1 more source

TIMP2 promotes AKI‐CKD transition by inducing tubular maladaptive repair and cell senescence via targeting Wnt/β‐catenin signalling

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
1. TIMP2 is upregulated in injured renal tubules and promotes maladaptive repair and cell senescence. 2. Genetic deletion of TIMP2 in tubular epithelial cells attenuates renal fibrosis and improves mitochondrial function. 3. TIMP2 activates Wnt/β‐catenin signalling by binding to LRP6 via an MMP‐independent mechanism.
Dongxue Xu, Haichuan Yu, Jingjing Pang, Xiaoyu Zhang, Jun Jiang, Yiming Li, Zhiyong Peng   +6 more
wiley   +1 more source

Mongolian medicine Wulanwendusu-11 alleviates myocardial ischemia-reperfusion injury by modulating the intestinal microbiota and associated metabolic pathways. [PDF]

Front Microbiol
Wuyunsiqin, Bai T, Yang D, Hashentuya, Namila, Jin C, Tana, Zhao P, Wang M, Menggenduxi.   +9 more
europepmc   +1 more source