Results 261 to 270 of about 107,803 (293)

S100a9 lactylation triggers neutrophil trafficking and cardiac inflammation in myocardial ischemia/reperfusion injury. [PDF]

J Clin Invest
Wang X, Yan X, Mang G, Chen Y, Liu S, Sui J, Tong Z, Wang P, Cui J, Yang Q, Zhang Y, Wang D, Sun P, Song W, Jin Z, Shi M, Zhao P, Yang J, Liu M, Wang N, Chen T, Ji Y, Yu B, Zhang M.   +23 more
europepmc   +1 more source

Huanglian Jiedu Decoction Alleviates Myocardial Ischemia-Reperfusion Injury via AKT-Mediated Regulation of Endoplasmic Reticulum Stress. [PDF]

J Inflamm Res
Gu M, Xu J, Liao Z, Lin J, Li R, Wu W, Qiu Y.   +6 more
europepmc   +1 more source

Cardioprotective Effects of Soluble Guanylate Cyclase and Its α1 Subunit on Myocardial Ischemia/Reperfusion Injury via the PGC-1α/UCP2 Pathway. [PDF]

J Cardiovasc Pharmacol
Li J, Li X, Chen Y, Fang L, Li Q, Wu H, Liu Y, Qi X, Wei L, Wei L.   +9 more
europepmc   +1 more source

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Purinergic signaling in myocardial ischemia–reperfusion injury

Purinergic Signalling, 2022
Purines and their derivatives, extensively distributed in the body, act as a class of extracellular signaling molecules via a rich array of receptors, also known as purinoceptors (P1, P2X, and P2Y). They mediate multiple intracellular signal transduction pathways and participate in various physiological and pathological cell behaviors.
Yi, Zhuang, Mei-Ling, Yu, Sheng-Feng, Lu
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Peroxynitrite in Myocardial Ischemia-Reperfusion Injury

Heart Failure Reviews, 2002
Peroxynitrite is a highly reactive oxidant which is produced during reperfusion of the ischemic heart. The role that this molecule plays in reperfusion injury has been controversial. Many investigations have demonstrated toxic effects of peroxynitrite, whereas others have found it to be protective during reperfusion.
Manoj M, Lalu, Wenjie, Wang, Richard, Schulz   +2 more
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Connexin43 and Myocardial Ischemia-Reperfusion Injury

Cardiovascular & Hematological Disorders-Drug Targets, 2018
Recently, the treatment and prevention of ischemic cardiomyopathy is one of the emerging research topics in the cardiovascular field. Gap junction is the basic structure of cardiac electrophysiology. Connexin is the basic unit of gap junctions. Connexin43(CX43) is the most abundant member of Cx family in the heart, the normal expression of Cx43 is ...
Lingyun, Zu, Ningxin, Wen, Changjie, Liu, Mingming, Zhao, Lemin, Zheng   +4 more
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C5aR-mediated myocardial ischemia/reperfusion injury

Biochemical and Biophysical Research Communications, 2007
The complement system activation can mediate myocardial ischemia and reperfusion (I/R). Inhibition of C5a activity reveals attenuation of I/R-induced myocardial infarct size. However, the contribution of C5a receptor (C5aR) to I/R injury remains to be unknown.
Haimou, Zhang, Gangjian, Qin, Gang, Liang, Jinan, Li, Robert A, Barrington, Dong-Xu, Liu   +5 more
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Zinc and myocardial ischemia/reperfusion injury

BioMetals, 2013
As an important trace element, zinc is required for the normal cellular structure and function, and impairment of zinc homeostasis is associated with a variety of health problems including cardiovascular disease. Zinc homeostasis is regulated through zinc transporters, zinc binding molecules, and zinc sensors.
Zhelong, Xu, Juan, Zhou
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Zingerone Alleviates Myocardial Ischemia/Reperfusion Injury

Current Topics in Nutraceutical Research, 2021
Using a rat model, we have explored the underlying mechanism of ischemia/reperfusion (I/R)-mediated myocardial infarction and assessed the protective potential of zingerone. The results show that zingerone exhibits not only the myocardial protective effect, but also antioxidative and anti-inflammatory effects by suppression of markers of oxidation and ...
Fanglin Luo, Shunxiang Luo, Yanqing Wu
openaire   +1 more source