Results 231 to 240 of about 100,863 (292)

Distinct profiles of mitochondrial bioenergetics and redox balance in left atrial and ventricular myocardium in the healthy rat heart

Experimental Physiology, EarlyView.
Abstract The left ventricle (LV) is the primary pumping chamber of the heart, generating high systolic pressure to sustain systemic circulation. LV contractile dysfunction is a hallmark of various cardiovascular diseases and is associated with mitochondrial dysfunction, characterised by decreased oxidative phosphorylation (OXPHOS) capacity and ...
Tingting Fang, Alex Chan, Janice Chew‐Harris, Toan Pham   +3 more
wiley   +1 more source

Selective ROCK2 inhibition reduces microvascular obstruction but does not reduce myocardial infarction after ischaemia and reperfusion. [PDF]

J Mol Cell Cardiol Plus
Pearce L, He D, Yellon DM, Davidson SM.
europepmc   +1 more source

The Impact of Transportation Mode on ST-Segment Elevation Myocardial Infarction (STEMI) Reperfusion Time and Survival [PDF]

Zeyad K. Aljaili, Ahmed A Alsalman, Abdulrahman G Aljabri, Rayyan O Turkestani, Mohammed H Alghanim, Fatima H Al Saeed, Bader Alossaimi, Dunya Alfaraj   +7 more
openalex   +1 more source

Senolytics and exercise: Dual modalities for rejuvenating muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican, Ce Qi, Uchenna Okpechi, Maya Strand Ford, Georgina M. Ellison‐Hughes   +4 more
wiley   +1 more source

Molecular and Cellular Mechanisms of Cardioplegic Protection in Surgical Myocardial Revascularization. [PDF]

Cells
Lazović DM, Karadžić Kočica M, Ivanišević D, Aleksić V, Kočica MJ, Grujić D, Mihajlović JM, Cvetković D, Juričić SA.   +8 more
europepmc   +1 more source

Mitochondrial oxidative stress, calcium and dynamics in cardiac ischaemia‐reperfusion injury

The Journal of Physiology, EarlyView.
Abstract figure legend Heart attack causes ischaemia–reperfusion injury in cardiomyocytes. Mitochondria generate reactive oxygen species (ROS), leading to oxidative stress. High levels of mitochondrial calcium (Ca2+) activate the mitochondrial permeability transition pore (mPTP), and excess ROS levels can lower the Ca2+ required to activate the mPTP ...
Emily Rozich, Ulas Ozkurede, Shanmugasundaram Pakkiriswami, Ryan Gemilere, Samira M. Azarin, Julia C. Liu   +5 more
wiley   +1 more source

Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation

The Journal of Physiology, EarlyView.
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson, Joan Escobar, Kira Kuraoka, Ian Venter, Cielo A. Carnate, Matthew W. Kay, David Mendelowitz, Kathryn J. Schunke   +7 more
wiley   +1 more source

Predictors of Impaired Reperfusion in ST-Elevation Myocardial Infarction Treated with Primary PCI: Preliminary Results from COMA.NET Project. [PDF]

Diagnostics (Basel)
Południewski M, Dąbrowski EJ, Pogorzelski P, Łuczaj M, Kobylińska J, Kruszyńska J, Kożuch M, Dobrzycki S.   +7 more
europepmc   +1 more source

Myocardial Ischemia-Reperfusion/Injury

, 2012
Saleh, Nermine, Youssef, Magda
openaire   +3 more sources

14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses

The Journal of Physiology, EarlyView.
Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley   +1 more source