Results 151 to 160 of about 68,817 (283)

Role of Histone Deacetylase and Inhibitors in Cardiovascular Diseases

Cell Proliferation, EarlyView.
HDACs play an important role in the occurrence and development of cardiovascular diseases, such as myocardial hypertrophy, hypertension, and atherosclerosis. HDAC inhibitors have broad prospects for the treatment of CVD, and different HDAC subtypes can act through different mechanisms.
Li‐Ying Zhang, Yue‐Yue Wang, Ri Wen, Tie‐Ning Zhang, Ni Yang   +4 more
wiley   +1 more source

Cardiac Muscle Membrane Stabilization in Myocardial Reperfusion Injury. [PDF]

JACC Basic Transl Sci, 2019
Houang EM, Bartos J, Hackel BJ, Lodge TP, Yannopoulos D, Bates FS, Metzger JM.   +6 more
europepmc   +1 more source

The Potential of Monoclonal Antibodies to Reduce Reperfusion Injury in Myocardial Infarction [PDF]

, 2001
Marcus E. McKenzie, Paul A. Gurbel
openalex   +1 more source

Cardiac troponin at the point of care in acute and chronic coronary syndromes

Diabetes, Obesity and Metabolism, EarlyView.
Abstract High‐sensitivity cardiac troponin (hs‐cTn) assays are integral to the assessment of patients with acute chest pain where prompt and accurate diagnosis of myocardial infarction enables timely delivery of potentially life‐saving treatment. In the Emergency Department, implementation of central laboratory hs‐cTn assays has reduced length of stay ...
Michael McDermott, Yong Yong Tew, Jamie G. Cooper, Deepak Harry, Nicholas L. Mills   +4 more
wiley   +1 more source

Identification of splenic IRF7 as a nanotherapy target for tele-conditioning myocardial reperfusion injury. [PDF]

Nat Commun
Long Q, Rabi K, Cai Y, Li L, Huang S, Qian B, Zhong Y, Qi Z, Zhang Y, Huang K, Wang X, Chang L, Xie W, Jiang H, Zhang H, Zhang J, Ren T, Wang Z, Teesalu T, Wu C, Lu L, Zhu Z, Chu Y, Santos HA, Liu Z, Zhao Q, Ye X.   +26 more
europepmc   +1 more source

Changes in Plasma Levels of ET-1 and its Precursor, Big ET-1, in the Arterial and Venous Circulation Following Double Myocardial Ischemia—Reperfusion Injury In Dogs

, 2000
Bruno Battistini, John G. Kingma
openalex   +1 more source

Bridging the gap in obesity research: A consensus statement from the European Society for Clinical Investigation

European Journal of Clinical Investigation, EarlyView.
This consensus highlights critical research gaps in obesity epidemiology, phenotypic heterogeneity and clinical management, calling for advanced methodologies, collaborative strategies and innovative policies to mitigate the global obesity epidemic and its socio‐economic impacts.
Federico Carbone, Jean‐Pierre Després, John P. A. Ioannidis, Ian J. Neeland, Gabriella Garruti, Luca Busetto, Luca Liberale, Stefano Ministrini, Gemma Vilahur, Thomas H. Schindler, Maria Paula Macedo, Agostino Di Ciaula, Marcin Krawczyk, Andreas Geier, Gyorgy Baffy, Maria Felicia Faienza, Ilaria Farella, Nicola Santoro, Gema Frühbeck, Patricia Yárnoz‐Esquiroz, Javier Gómez‐Ambrosi, Emma Chávez‐Manzanera, Verónica Vázquez‐Velázquez, Jean‐Michel Oppert, Dimitrios N. Kiortsis, Paolo Sbraccia, Carmine Zoccali, Piero Portincasa, Fabrizio Montecucco   +28 more
wiley   +1 more source

Mitochondrial transplantation combined with mitoquinone and melatonin: A survival strategy against myocardial reperfusion injury in aged rats. [PDF]

Exp Physiol
Mokhtari B, Delkhah M, Badalzadeh R, Ghaffari S.   +3 more
europepmc   +1 more source

Myocardial reperfusion injury and oxidative stress: Therapeutic opportunities. [PDF]

World J Cardiol, 2018
González-Montero J, Brito R, Gajardo AI, Rodrigo R.   +3 more
europepmc   +1 more source

Cardioprotective effects of the extracellular chaperone clusterin in acute myocardial infarction

European Journal of Clinical Investigation, EarlyView.
In vivo, CLU−/− mice were more susceptible to acute myocardial infarction than CLU+/+ mice. Moreover, inflammation and histone levels were significantly increased in CLU−/− mice compared to CLU+/+ mice following ischemia/reperfusion. In vitro, CLU protects cardiomyocytes from histone‐ and/or hypoxia‐induced cell death.
Louwana Allawa, Antoine Poirier, Pascale Pignon, Justine Beaumont, Lucie Lebeau, Agnès Barbelivien, Thomas Bochaton, Céline Beauvillain, Daniel Henrion, Yves Delneste, Pascale Jeannin, Fabrice Prunier, Sophie Tamareille   +12 more
wiley   +1 more source