Results 171 to 180 of about 1,258,622 (242)

Dynamic Variability of Sodium and Potassium Predicts Mortality in Critically Ill Patients With Ischemic Stroke: Evidence From Two Critical Care Cohorts

Brain and Behavior, Volume 16, Issue 9, September 2026.
ABSTRACT Background Ischemic stroke (IS) is one of the leading causes of death and long‐term disability worldwide. Electrolyte fluctuations, particularly in sodium and potassium, may play a critical role in the mortality of IS. Methods This retrospective cohort study utilized the MIMIC‐IV database and NWICU to examine the association between sodium and
Jian Zhang, Wei Zhang, Bin Zeng, Linfeng Xie, Jianjun Zhu   +4 more
wiley   +1 more source

Activation of the cGAS-STING Pathway by NETs Promotes Inflammatory Injury in Myocardial Ischemia-Reperfusion. [PDF]

J Inflamm Res
Jiang J, Wu H, Zhou L, Wu S, Li Y, Tang D.   +5 more
europepmc   +1 more source

Revising NHE‐1: From Cardiac Homeostasis to Heart Failure and Future Drug Development

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT NHE‐1 is a Na+/H+ exchanger that receives phosphorylation signals, binds calmodulin and responds to neurohormonal input from angiotensin II, endothelin‐1, and adrenergic pathways. In cardiac myocytes, NHE‐1 maintains pH homeostasis and couples to Na+/Ca2+ exchange and mitochondrial ion handling. During heart disease sustained activation drives
Vasileios Bouratzis, Nikoleta Douskou, Nikolaos P. Tzavellas, Yannis V. Simos, Petros Bozidis, Konstantinos I. Tsamis, Georgios S. Markopoulos, Dimitrios Peschos, Lampros Lakkas   +8 more
wiley   +1 more source

Does exercise modulate ferroptosis-related cardiovascular injury? Mechanistic evidence and translational boundaries. [PDF]

Front Physiol
Han M, Huang H, Li Y, Wang L, Ji L, Yin H, Fan P, Yuan X.   +7 more
europepmc   +1 more source

Histone Post‐Translational Modifications Regulating Ferroptosis: The Molecular Mechanisms and Disease Associations

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT Ferroptosis is a form of programmed cell death characterized by iron‐dependent phospholipid peroxidation and is implicated in a wide range of human diseases. Emerging evidence highlights the critical role of epigenetic regulation in this process.
Xiaoqian Tang, Haodang Luo, Siqi Gao, Xiaocheng Liu, Qing Sun, Yanhua Zeng   +5 more
wiley   +1 more source

WTAP Histone Lactylation Drives the YTHDF1/ALOX15 Axis to Regulate Ferroptosis in Myocardial Ischemia-Reperfusion Injury. [PDF]

FASEB J
Liu W, Wang Y, Wu J, He C, Zhou Z.
europepmc   +1 more source

The High‐Sensitivity C‐Reactive Protein−Albumin−Lymphocyte Index Is a Prognostic Marker for All‐Cause and Cardiovascular Mortality in Patients With ST‐Elevation Myocardial Infarction

Catheterization and Cardiovascular Interventions, Volume 108, Issue 3, Page 1034-1046, September 1, 2026.
ABSTRACT Background Inflammation and immune dysfunction may worsen the prognosis of patients with ST‐segment elevation myocardial infarction (STEMI). Aims This study aimed to assess whether the high‐sensitivity C‐reactive protein–albumin–lymphocyte index (hsCALLYI) could be used to predict the prognosis of STEMI patients who received emergency ...
Xinuo Ma, Wei Zhang, Ningli Zhang, Qinghua Zhong, Tao Shi, Sirui Yang, Fazhi Yang, Yujuan Peng, Lixing Chen   +8 more
wiley   +1 more source

MITF Regulates CFTR Expression to Participate in Myocardial Ischemia-Reperfusion Injury. [PDF]

J Gene Med
Tang B, Zhu C, Wang H, Gao M, Li T.
europepmc   +1 more source

Angiography‐Negative Subarachnoid Hemorrhage Detected After Emergent Percutaneous Coronary Intervention for Non‐ST‐Segment Elevation Myocardial Infarction: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Neurological deterioration, headache, vomiting, bradycardia, or hypertension after emergent percutaneous coronary intervention should prompt immediate brain imaging. When subarachnoid hemorrhage is detected shortly after coronary stenting, the hemorrhage onset may remain uncertain, and antiplatelet decisions require individualized ...
Chul Hee Lee
wiley   +1 more source

SUMO2 deficiency impairs endogenous regulation of oxidative stress and apoptosis in myocardial ischemia-reperfusion injury. [PDF]

Front Cell Dev Biol
Zhang X, Zhao W, Zhao J, Fan N, Wang Y, Xu A, Yang W, Rong J.   +7 more
europepmc   +1 more source