Results 161 to 170 of about 1,258,622 (242)

LncRNA DLX6-AS1 promotes necroptosis through PI3K/AKT/mTOR signaling pathway in myocardial ischemia/reperfusion injury mice. [PDF]

Sci Rep
Su Y, Mu L, Wang L, Li T, Zhang Q, Zhang J.   +5 more
europepmc   +1 more source

The role of macrophage migration inhibitory factor (MIF) in the pathogenesis and progression of cardiovascular disease

British Journal of Pharmacology, Volume 183, Issue 19, Page 5732-5751, October 2026.
Abstract Cardiovascular disease (CVD) remains the leading global cause of death, driven by complex mechanisms, in which chronic inflammation plays a central role. Inflammatory pathways contribute to all stages of CVD, from endothelial dysfunction and plaque formation to erosion, rupture and myocardial injury.
Shreya Mahabhashyam, James Harris, Jürgen Bernhagen, Antony Vinh, Katrina M. Mirabito Colafella   +4 more
wiley   +1 more source

Oxidative Stress and Its Impact on Reperfused Myocardium: Pathophysiological Insights and Therapeutic Perspectives. [PDF]

Cells
Bararu Bojan I, Plesoianu C, Vladeanu MC, Dobreanu S, Tesoi DF, Badescu C, Foia CI, Frasinariu OE, Iliescu D, Badulescu OV, Iliescu Halitchi CO, Bazyani A, Ciocoiu M.   +12 more
europepmc   +1 more source

Annexin A4 Deficient Ventricular Myocytes Display Advanced Hypertrophy and Electrical Remodeling With Chronic β‐Adrenoceptor Stimulation

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
Annexin A4 (A4) inhibits adenylyl cyclase 5 and may protect the heart during chronic β‐adrenergic stress. After 7 days of isoprenaline, A4‐deficient mice showed greater cardiomyocyte hypertrophy, prolonged action potentials, reduced Ito, preserved ICaL with altered activation, increased NCX1, and enhanced acute cAMP responsiveness compared with wild ...
Florentina Pluteanu, Alexander Heinick, Manuel Domnik‐Lehnert, Frank U. Müller, Christina Hermes   +4 more
wiley   +1 more source

Effects of serotonin transporters on myocardial cell injury during ischemia/reperfusion in rats. [PDF]

J Physiol Sci
Kishi Y, Shimizu S, Kuroko Y, Kotani Y, Akiyama T, Kasahara S.   +5 more
europepmc   +1 more source

Enhancing Blood Circulation With Epsilon‐Near‐Zero (ENZ) Materials via the Far‐Infrared Window of Human Skin

Advanced Science, Volume 13, Issue 49, 3 September 2026.
Epsilon‐near‐zero (ENZ) silicon carbide enables a selective far‐infrared emitter spectrally aligned with the human skin window around 10 µm for wavelength‐matched thermal therapy. In 25 within‐subject trials (50 hands) monitored by laser speckle contrast imaging, SiC increases blood perfusion by 30.2% versus a broadband graphite emitter while ...
Wen‐Teng Yao, Shan‐Chiao Yang, Ming‐Feng Tsai, Hsuen‐Li Chen   +3 more
wiley   +1 more source

Rg1-Loaded Tetrahedral DNA Nanostructures Attenuate Myocardial Ischemia-Reperfusion Injury by Suppressing Oxidative and Endoplasmic Reticulum Stress. [PDF]

Int J Nanomedicine
Lin F, Huang J, Chen Z, Zhong F, Xu L, Liu N, Gan M, Yin H, Li Z, Zhang X, Song Y, Wang X, Zhuo H, Shang H, Lin S, Zeng Z, Yang R.   +16 more
europepmc   +1 more source

Engineering CAR‐Macrophages With Advanced Delivery Systems for Tissue Repair

Advanced Science, Volume 13, Issue 51, 14 September 2026.
This review highlights how engineered macrophages equipped with chimeric antigen receptors (CAR) guide tissue repair by recognizing disease‐related targets, clearing harmful cells, and reshaping local immune environments. It summarizes macrophage biology, CAR design, delivery platforms, and functionalization strategies, and discusses emerging ...
Yixin Zhang, Jintian Yu, Liang Yuan, Ziliang Fu, Yiming Yao, Lingna Chen, Shixiong Chen, Aikemu Ainiwaer, Xiaolin Cui   +8 more
wiley   +1 more source

Tunable Regional Targeting of Self‐Assembling Peptide Nanomaterials in Acute Myocardial Infarction

Advanced NanoBiomed Research, Volume 6, Issue 9, September 2026.
In a rat model of acute myocardial infarction, intravascular delivery of peptide nanofibers with a collagen‐targeting peptide bound to the infarct vasculature while globular peptide nanoparticles penetrated into the infarct area. This study demonstrated that size, shape, and surface chemistry of nanomaterials control the delivery location within the ...
Alexander Chen, Michael B. Nguyen, Elliot Widd, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Houston Harding, Chloe Hurteau, Anika Yogi, Colin Luo, Rebecca L. Braden, Pedro Cabrales, Karen L. Christman   +14 more
wiley   +1 more source

Remote electroacupuncture conditioning protects the heart via fine-tuning the dual role of the SDF-1α/CXCR4 axis in myocardial ischemia-reperfusion injury. [PDF]

Chin Med
Xu S, Lian J, Chen S, Zuo Y, Xiong H, Lin Y, Gu Y, Zhang H.   +7 more
europepmc   +1 more source