Results 171 to 180 of about 131,479 (353)

[Retracted] Effects of Aspirin on Myocardial Ischemia‐Reperfusion Injury in Rats through STAT3 Signaling Pathway [PDF]

, 2021
Zhenjun Wu, Xuewen Li, Xiuyue Li, Lihua Yu   +3 more
openalex   +1 more source

Electrocardiographic manifestation of cardiac repolarization dispersion [PDF]

, 2019
Alterations of repolarization heterogeneity in the heart have been established as anAlterations of repolarization heterogeneity in the heart have been established as ...
Sedova Ksenia
core  

RBMX Transcriptionally Repressed by EZH2‐Associated H3K27me3 Modification Attenuates Pyroptosis in Renal Ischemia/Reperfusion Injury via Regulating SIRT3/NLRP3 Inflammasome Activation

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ischemic reperfusion injury (IRI) to kidney is a significant clinical factor in acute kidney injury (AKI). This study aimed to investigate the new role of RNA‐binding motif protein X‐linked (RBMX), a modulator of m6A methylation, in renal IRI and to examine the associated regulatory mechanisms. An in vitro renal IRI model was established using
Yi‐Han Wang, Yan Teng, Fang‐Lan Yao, Shu‐Qi Wei, Yan Li   +4 more
wiley   +1 more source

Role of the complement components C5 and C3a in a mouse model of myocardial ischemia and reperfusion injury

GMS German Medical Science, 2010
Objective: Ischemic heart disease is the leading cause of death worldwide. The complement system plays a major role in inflammation and tissue injury following myocardial ischemia and reperfusion (MI/R) injury.
Stahl, Gregory L., Busche, Marc N.
doaj  

Postconditioning with Nitrates Protects Against Myocardial Reperfusion Injury: A New Use for an Old Pharmacological Agent. [PDF]

Med Sci Monit, 2020
Meng Z, Gai W, Song D.
europepmc   +1 more source

Attenuation of myocardial reperfusion injury in pigs by Mirococept, a membrane-targeted complement inhibitor derived from human CR1 [PDF]

, 2017
Objectives Membrane-targeted application of complement inhibitors may ameliorate ischemia/reperfusion (I/R) injury by directly targeting damaged cells. We investigated whether Mirococept, a membrane-targeted, myristoylated peptidyl construct derived from
Banz, Yara, Csizmadia, Eva, Haeberli, André, Hess, Otto M., Meier, Pascal, Mettler, Daniel, Rieben, Robert, Robson, Simon C., Shaw, Sidney, Smith, Richard A.   +9 more
core  

METTL14 Regulates Myocardial Infarction Progression via m6A‐Dependent Modulation of OTUD1‐Mediated Deubiquitination of DUSP6

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Myocardial infarction (MI) is the most severe clinical manifestation of coronary artery diseases (CVD) and serves as a critical driver of sudden cardiac death and heart failure (HF). Its pathophysiology begins with the abrupt cessation of coronary blood flow, leading to severe ischemia and subsequent cardiomyocyte necrosis. This study aimed to
Cheng‐Cheng Wei, Ya‐Fang Shen, Jin‐Yu Zhang   +2 more
wiley   +1 more source

Early Dapagliflozin and Melatonin Treatment Ameliorated LV Fibrosis via Suppressing TGF‐β1/Smads and Activating Nrf2‐ARE Signaling in MI Rodent

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study tested whether combined dapagliflozin (DAPA) and melatonin (Mel) therapy was superior to merely one for ameliorating the left ventricular (LV) fibrosis/remodeling and improving LV ejection fraction (LVEF) in rats after acute myocardial infarction (AMI). In vitro study demonstrated that DAPA treatment significantly suppressed the TGF‐
Jiunn‐Jye Sheu, Jui‐Ning Yeh, Han‐Tan Chai, John Y. Chiang, Chi‐Ruei Huang, Jun Guo, Hon‐Kan Yip   +6 more
wiley   +1 more source

Long non-coding RNA-AK138945 regulates myocardial ischemia-reperfusion injury via the miR-1-GRP94 signaling pathway

Frigid Zone Medicine
Myocardial ischemia-reperfusion injury (MIRI) is one of the leading causes of death from cardiovascular disease in humans, especially in individuals exposed to cold environments.
Wang Yanying, Huang Jian, Sun Han, Liu Jie, Shao Yingchun, Gong Manyu, Yang Xuewen, Liu Dongping, Wang Zhuo, Li Haodong, Zhang Yanwei, Zhang Xiyang, Du Zhiyuan, Leng Xiaoping, Jiao Lei, Zhang Ying   +15 more
doaj   +1 more source

Selective Localization of a Novel Dendrimer Nanoparticle in Myocardial Ischemia-Reperfusion Injury [PDF]

, 2017
J. Trent Magruder, Todd C. Crawford, Yi-An Lin, Fan Zhang, Joshua C. Grimm, Rangaramanujam M. Kannan, Sujatha Kannan, Christopher M. Sciortino   +7 more
openalex   +1 more source