Results 191 to 200 of about 68,817 (283)

Bioactive Compounds, Their Mechanisms of Action, and Cardioprotective Effects of Pomegranate (Punica granatum): A Comprehensive Review

eFood, Volume 6, Issue 4, August 2025.
Pomegranate parts (arils, peel, and flower) contain antioxidants, polyphenols, and flavonoids. These bioactives reduce inflammation, improve endothelial function, and modulate lipids. Regular intake lowers blood pressure, LDL, and atherosclerotic plaque while increasing HDL.
Esha Saeed, Farah Javed, Zoya Rana, Rashida Perveen, Iftikhar Younis Mallhi, Izza Amjad, Quratulain Maqsood, Nauman Ali Chaudhary, Saleha Binte Tahir, Arooj Fatima, Noor Fatima Rasheed, Esther Ugo Alum   +11 more
wiley   +1 more source

Complement and Polymorphonuclear Leukocyte Activation Each Play a Role in Determining Myocardial Ischemia - Reperfusion Injury

, 2001
Toru Atsuumi, Hiroyuki Yaoita, Tsutomu Shichishima, Kazuhira Maehara, Teizo Fujita, Yukio Maruyama   +5 more
openalex   +2 more sources

Neuraminidase 1 Exacerbated Glycolytic Dysregulation and Cardiotoxicity by Destabilizing SIRT1 through Interactions with NRF2 and HIF1α

Advanced Science, Volume 12, Issue 25, July 3, 2025.
NEU1, a key regulator of glycolysis, is markedly upregulated following DOX treatment. This upregulation is attributed to HIF1α’s transcriptional repression, requiring intricate interactions with NRF2. Increased NEU1 facilitates SIRT1 lysosomal degradation, contributing to aberrant glycolytic phenotype and cardiac damage.
Ting Gao, Yufeng Tang, Tao Zeng, Jie Wang, Xiaohui Zhang, Qingbo Liu, Xun Guan, Xinyu Tang, Guangping Lu, Jiahao Li, Mingrui Liu, Dongmei Zhang, Sixuan Lv, Junlian Gu   +13 more
wiley   +1 more source

The Role of Myocardial Gap Junction in Ischemia-Reperfusion Injury in Senescent Rabbit Myocardium.

, 2001
Yasunari Nakai, Hitoshi Horimoto, Hiroaki Shimomura, Tetsuya Hayashi, Yasushi Kitaura, Keiichiro Kondo, Kunio Asada, Shinjiro Sasaki   +7 more
openalex   +2 more sources

CNPY2 Aggravates Renal Tubular Cell Ferroptosis in Diabetic Nephropathy by Regulating PERK/ATF4/CHAC1 Pathway and MAM Integrity

Advanced Science, Volume 12, Issue 25, July 3, 2025.
Canopy FGF signaling regulator 2 (CNPY2) which is contributed to ERS is upregulated in the renal tubules of patients with diabetic nephropathy (DN). Mechanistically, CNPY2 may regulate ferroptosis and MAM integrity in renal tubular epithelial cells through PERK/ATF4/CHAC1 pathway, thereby promoting the progression of DN.
Jingfang Chen, Dongwei Liu, Lei Lei, Ting Liu, Shaokang Pan, Hui Wang, Yong Liu, Yingjin Qiao, Zhangsuo Liu, Qi Feng   +9 more
wiley   +1 more source

Relationship between ST segment elevation after acute myocardial infarction and microvascular reperfusion injury evaluated with myocardial contrast echocardiography Paolo Colonna, Abdel Hakeem Seleem, Marco Orr�, Chrisian Cadeddu, Roberta Montisci, Lijun Chen, Enrico Onnis, Luigi Meloni, Sabino Iliceto. Department of Cardiovascular and neurological Sciences, University of Cagliari, Cagliari, Italy

, 2001

openalex   +1 more source

Gap junction-mediated spread of cell injury and death during myocardial ischemia–reperfusion [PDF]

, 2004
David García‐Dorado
openalex   +1 more source

The FGF13‐Caveolin‐1 Axis: A Key Player in the Pathogenesis of Doxorubicin‐ and D‐Galactose‐Induced Premature Cardiac Aging

Advanced Science, Volume 12, Issue 25, July 3, 2025.
The FGF13 level is significantly downregulated in premature aging murine hearts subject to D‐galactose and Doxorubicin. FGF13 overexpression and deficiency exacerbated and alleviated Doxorubicin/D‐galactose‐induced myocardial aging characteristics and functional impairment, respectively.
Enzhao Shen, Yuecheng Wu, Weijian Ye, Sihang Li, Junjie Zhu, Meifan Jiang, Zhicheng Hu, Gaoyong Cao, Xiaojing Yi, Fan Li, Zhouhao Tang, Xiaokun Li, Kwang Youl Lee, Litai Jin, Xu Wang, Weitao Cong   +15 more
wiley   +1 more source

Inhibition of mannose binding lectin reduces myocardial reperfusion injury: A role for the lectin complement pathway in cardiovascular disease James E. Jordan, Gregory L. Stahl. CET&RI, Dept. of Anesthesia, Brigham, and Women's Hospital, Boston, MA

, 2001

openalex   +1 more source

Myocardial Reperfusion Injury: Etiology, Mechanisms, and Therapies [PDF]

, 2004
John W. Hoffman, Timothy B. Gilbert, Robert S. Poston, Erik P. Silldorff   +3 more
openalex   +1 more source