Results 131 to 140 of about 770,795 (181)
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Therapy of myocardial stunning
Basic Research in Cardiology, 1997Since in the clinical setting stunning may coexist with persistently ischemic and infarcting myocardium, the ben fit el therapeutic interventions on the stunned myocardium must be weighed against potential deleterious effects on the ischemic myocardium.
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Independency of myocardial stunning of endothelial stunning?
Basic Research in Cardiology, 2007Vascular endothelial cells play an important role in the control of vascular tone. The reasons for coronary endothelial dysfunction are complex and may involve ischemia/reperfusion injury. We investigated whether endothelial, smooth muscle, and myocardial dysfunction are independent phenomena.Rabbit hearts were rapidly excised without intermittent ...
Solange C, Garcia +4 more
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Energy metabolism in myocardial stunning
Journal of Molecular and Cellular Cardiology, 1992We investigated the effect of reversible ischemia, leading to persistent contractile dysfunction (stunning), on myocardial energy metabolism. The balance of energy metabolism is expressed by the phosphorylation state of cytosolic nucleotides. This variable cannot be measured directly because of nucleotide compartmentation, but in the isolated heart it ...
ZUCCHI, RICCARDO +4 more
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Mitochondrial function in myocardial stunning
Journal of Molecular and Cellular Cardiology, 1991Mitochondrial respiration parameters were studied in mitochondria isolated from normal, ischemic and post-ischemic rabbit hearts. Mitochondrial function was related to tissue content of high energy phosphates (HEP) and cardiac function in the isolated working rabbit heart preparation.
W, Flameng +4 more
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Cellular Mechanisms of Myocardial Stunning
Annual Review of Physiology, 1992Stunning describes the impairment of contraction observed in myocardium that has been reperfused after brief periods of ischemia (12, 31, 90). The critical feature of the definition lies in the premise that no permanent injury has occurred; hence, stunning resolves entirely, albeit slowly (hours to days; 12).
H, Kusuoka, E, Marban
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Role of Adenosine in the Treatment of Myocardial Stunning
Cardiovascular Drugs and Therapy, 1991Adenosine is an endogenous nucleoside produced from the breakdown of adenosine triphosphate (ATP) that possesses a number of complex cellular and metabolic effects that could ameliorate postischemic contractile dysfunction (myocardial stunning). Potential mechanisms include the repletion of high-energy phosphate stores, reduced myocardial oxygen ...
M B, Forman, C E, Velasco
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The spectrum of post-myocardial infarction care: From acute ischemia to heart failure.
Progress in cardiovascular diseasesHeart failure (HF) is the leading cause of mortality in patients with acute myocardial infarction (AMI), with incidence ranging from 14% to 36% in patients admitted due to AMI.
K. Akhtar +7 more
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Myocardial “Stunning” and Substrate Metabolism
Journal of Cardiac Surgery, 1994Although many experts have dismissed myocardial substrate metabolism as having a role in the phenomenon known as "myocardial stunning," recent studies using the isolated perfused working rat heart (especially from Lopaschuk's laboratory) have provided evidence that perhaps there is a role for alterations in myocardial substrate metabolism in producing ...
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Myocardial stunning after cerebral infarction
International Journal of Cardiology, 1997Myocardial stunning has not been described in patients with cerebrovascular accidents. We present a patient in whom inferior wall hypokinesis, ST-segment elevations and Q waves developed after acute right hemisphere ischemic stroke. Total recovery ensued within 5 days. Coronary vasospasm induced by stroke-related sympathetic surge might be the cause of
T D, Wang, C C, Wu, Y T, Lee
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Effect of Adenosine on Myocardial ‘Stunning’ in the Dog
Circulation Research, 1995AbstractRecent evidence suggests a cardioprotective effect of adenosine in myocardial ischemia and reperfusion. The present study was undertaken to determine (1) whether adenosine attenuates myocardial stunning, (2) if so, whether the beneficial effect of adenosine takes place during ischemia or after reperfusion, and (3) whether adenosine ...
S, Sekili +5 more
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