Nutrient starvation triggers pyroptosis with cleavage of pro‐IL‐18 and GSDMD in pancreatic cancer cells, and treatment of 5‐FU enhances this process. As a result, active IL‐18 is released and leads to inflammation. ABSTRACT Interleukin‐18 (IL‐18) is a pro‐inflammatory cytokine, and higher IL‐18 expression in pancreatic tumors is associated with poor ...
Hiroki Kamino +2 more
wiley +1 more source
Post-marketing safety assessment of epinephrine: an analysis of the US FDA adverse event reporting system. [PDF]
Yan B, Xiao Q, Jiang Y.
europepmc +1 more source
SORBS2: A Molecular Nexus in Multisystem Diseases Through Scaffold‐Mediated Regulation
ABSTRACT Sorbin and SH3 Domain Containing 2 (SORBS2), a multifunctional scaffold protein harbouring Sorbin homology (SoHo) and Src homology 3 (SH3) domains, serves as a molecular hub in human diseases by integrating cytoskeletal remodelling, signal transduction and RNA metabolic regulation. This study systematically analyses SORBS2's molecular features,
Qiwei Jia, Yong Zhang
wiley +1 more source
Ischaemic preconditioning regulates cardiac transcriptome via DNA methylation conferring cardio-protection from ischaemic reperfusion injury. [PDF]
Khan AW +10 more
europepmc +1 more source
Modulation of determinants of myocardial function and energetics by stunning and heart failure
Dongsheng Fan
openalex +1 more source
Research Topics and Trends in MIMIC‐IV: A Large ICU Database Relevant for Critical Care Nursing
ABSTRACT Background The Medical Information Mart for Intensive Care‐IV (MIMIC‐IV) clinical database has become a central resource for data‐driven critical care research, enabling advances in clinical informatics, machine learning and nursing science.
Yuh‐Shan Ho +5 more
wiley +1 more source
Comparative Meta-Analysis of Left Ventricular Mechanics in Takotsubo Syndrome and Anterior STEMI Due to Left Anterior Descending Artery Occlusion. [PDF]
Sonaglioni A +4 more
europepmc +1 more source
ABSTRACT Background Pulmonary vein isolation (PVI) using thermal energy—radiofrequency (RF) or cryoablation (CRYO)—is associated with direct myocardial injury and collateral neural damage. In contrast, pulsed electric field (PEF) energy has emerged as a neural‐sparing alternative.
Predrag Stojadinović +12 more
wiley +1 more source
Takotsubo Syndrome Following Emergency Decompression for Acute Cervical Spinal Epidural Hematoma: A Case Report. [PDF]
Takayama K, Ono Y, Yamada I, Kotani J.
europepmc +1 more source
Post‐ROSC ST‐Segment Elevation: A Diagnostic Pitfall in Cardiac Arrest Survivors
Annals of Noninvasive Electrocardiology, Volume 31, Issue 3, May 2026.
Oğuz Kaan Kaya
wiley +1 more source

