Expression and Activity Patterns of Nitric Oxide Synthases and Antioxidant Enzymes Reveal a Substantial Heterogeneity Between Cardiac and Vascular Aging in the Rat [PDF]
, 2018 We investigated the effects of aging and ischemia-reperfusion (I/R) injury on the expression and activity of nitric oxide (•NO) synthases and superoxide dismutase (SOD) isoforms. To this end we perfused excised hearts from young (6months old) and old (31-
van der Loo, Bernd +7 more
core +3 more sources
Reperfusing the myocardium - a damocles Sword
Indian Heart Journal, 2018 Return of blood flow after periodic ischemia is often accompanied by myocardial injury, commonly known as lethal reperfusion injury (RI). Experimental studies have shown that 50% of muscle die of ischemia and another 50% die because of reperfusion. It is
V.K. Shah, K.K. Shalia
doaj +1 more source
Assessment of poststress left ventricular ejection fraction by gated SPECT: comparison with equilibrium radionuclide angiocardiography [PDF]
, 2010 PURPOSE: We compared left ventricular (LV) ejection fraction obtained by gated SPECT with that obtained by equilibrium radionuclide angiocardiography in a large cohort of patients.
ACAMPA, WANDA +8 more
core
Mechanical Stress Triggers Premature Senescence in Cardiac Fibroblasts
Advanced Science, EarlyView.Cellular senescence contributes to disease burden in cardiovascular disease (CVD) and aging, highlighting the need to understand its induction. In primary cardiac fibroblasts, reduced strain and increased frequency, mimicking CVD, elicit a distinct senescent phenotype compared to oxidative stress.
Stephanie E. Schneider +5 more
wiley +1 more source
Reviews in Cardiovascular Medicine, 2023 Myocardial perfusion single photon emission computed tomography (SPECT) is widely used in assessing coronary artery disease (CAD) owing to its proven efficacy in extensive clinical experience.
Caterina Maffeis +4 more
doaj +1 more source
Aetiology of sudden cardiac death in sport: a histopathologist's perspective. [PDF]
, 2012 In the UK, when a young person dies suddenly, the coroner is responsible for establishing the cause of death. They will ask a consultant pathologist to carry out an autopsy in order to ascertain when, where and how that person died.
Sheppard, MN
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Nanozymes for Non‐Neoplastic Diseases: Catalytic Therapy Redefined
Aggregate, EarlyView.Non‐neoplastic diseases pose a significant health burden. Nanozymes, enzyme‐like nanomaterials, offer promising strategies for regulating oxidative stress and inflammation. This review explores their development, structure–function relationships, and therapeutic potential, with a focus on precision medicine through targeted delivery and multimodal ...
Ling Mei +8 more
wiley +1 more source
Left Ventricular Dysfunction in Ischemic Heart Disease
Cardiovascular Innovations and Applications, 2019 Ischemic heart disease is a growing cause of heart failure owing to the increasing prevalence of diabetes, hypertension, and obesity. It is important to understand the concepts of myocardial stunning and hibernation so we as physicians can order ...
Robert F. Hamburger
doaj +1 more source
Stretch‐Induced Increase in Cardiac Contractility Is Independent of Myocyte Ca\u3csup\u3e2+\u3c/sup\u3e While Block of Stretch Channels by Streptomycin Improves Contractility After Ischemic Stunning [PDF]
, 2015 Stretching the cardiac left ventricle (LV) enhances contractility but its effect on myoplasmic [Ca2+] is controversial. We measured LV pressure (LVP) and [Ca2+] as a function of intra-LV stretch in guinea pig intact hearts before and after 15 min global ...
Aldakkak, Mohammed +4 more
core +1 more source
Current state of knowledge on Takotsubo Syndrome: a Position Statement from the Taskforce on Takotsubo Syndrome of the Heart Failure Association of the European Society of Cardiology [PDF]
, 2015 Takotsubo syndrome is an acute reversible heart failure syndrome that is increasingly recognized in modern cardiology practice. This Position Statement from the European Society of Cardiology Heart Failure Association provides a comprehensive review of ...
Akashi, YJ +13 more
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