Results 191 to 200 of about 57,090 (240)
Abstract Background Treatment‐resistant schizophrenia (TRS) is often accompanied by poor insight and impaired decision‐making capacity (DMC), complicating the initiation of clozapine (CLZ) despite clear clinical indications. In Japan, CLZ utilization is markedly lower than in many foreign countries, partly due to concerns about adverse effects ...
Shimpei Hanaoka +2 more
wiley +1 more source
ABSTRACT Background Traditional pharmacovigilance systems have limitations in detecting common adverse drug reactions. We investigated whether real‐world data (RWD) could have detected rofecoxib's cardiovascular adverse effects earlier using nested case–control (NCC) and case‐crossover (CCO) designs.
Donya Moslemzadeh +5 more
wiley +1 more source
Abstract Non‐immune hydrops fetalis (NIHF) can result from a multitude of underlying causes, such as fetal genetic diseases, congenital anomalies, infections, fetal arrhythmias, placental tumors, monochorionic twin complications, and other disorders.
Society for Maternal‐Fetal Medicine (SMFM) +3 more
wiley +1 more source
Zidovudine to prevent mother-to-infant HIV transmission in developing countries: a view from Thailand. [PDF]
Cawthorne, P +6 more
core +1 more source
ABSTRACT Idiopathic pulmonary fibrosis (IPF) is a serious progressive complication of the respiratory system, which is profoundly associated with persistent extracellular matrix (ECM) deposition, fibrosis, and disrupted tissue regeneration. Emerging evidence shows that epithelial–mesenchymal transition (EMT) acts as a key factor in the pathogenesis of ...
Ningzi Zang +9 more
wiley +1 more source
Abstract Elevated beta‐hydroxybutyrate (BHB) is a marker for ketoacidosis. Post‐mortem values for the diagnosis of fatal ketoacidosis and the associated clinical and histologic findings are limited in the pediatric population. A retrospective case series of pediatric autopsy records and histology slides was conducted.
Nasim Haghandish +3 more
wiley +1 more source
Incidents of sudden death during restraint of agitated individuals in Sweden between 1992 and 2024
Abstract Restraint‐related sudden deaths in agitated individuals raise complex questions at the intersection of medicine and law. Hyperactive delirium with extreme agitation as well as positional asphyxia due to restraint have been proposed to account for these deaths. However, the exact physiological mechanisms responsible and to what extent restraint
Alexander Tyr +4 more
wiley +1 more source
Immortal time bias (ITB)–adjusted landmark and time‐dependent Cox analyses showed that immune‐related adverse events (irAEs) were not associated with improved survival in NSCLC patients receiving first‐line immune checkpoint inhibitors. ECOG performance status remained the key prognostic factor.
Yoshiki Kuwabara +20 more
wiley +1 more source

