Results 11 to 20 of about 103,145 (303)

Glycogen synthase kinases 3α and 3β in cardiac myocytes: regulation and consequences of their inhibition [PDF]

open access: yes, 2008
Inhibition of glycogen synthase kinase 3β (GSK3β) as a consequence of its phosphorylation by protein kinase B/Akt (PKB/Akt) has been implicated in cardiac myocyte hypertrophy in response to endothelin-1 or phenylephrine.
Alsafi, Ali   +7 more
core   +1 more source

Junctional sarcoplasmic reticulum motility in adult mouse ventricular myocytes. [PDF]

open access: yes, 2020
Excitation-contraction (EC) coupling is the coordinated process by which an action potential triggers cardiac myocyte contraction. EC coupling is initiated in dyads where the junctional sarcoplasmic reticulum (jSR) is in tight proximity to the sarcolemma
de la Mata, Ana   +5 more
core   +2 more sources

KV4.3 Expression Modulates NaV1.5 Sodium Current

open access: yesFrontiers in Physiology, 2018
In cardiomyocytes, the voltage-gated transient outward potassium current (Ito) is responsible for the phase-1 repolarization of the action potential (AP).
Vincent Portero   +6 more
doaj   +1 more source

MicroRNAs in Sarcopenia: A Systematic Review

open access: yesFrontiers in Medicine, 2020
Sarcopenia, which is characterized by the loss of skeletal muscle, has been reported to contribute to development of physical disabilities, various illnesses, and increasing mortality. MicroRNAs (miRNAs) are small non-coding RNAs that inhibit translation
Katsunori Yanai   +9 more
doaj   +1 more source

The myogenic kinome: protein kinases critical to mammalian skeletal myogenesis

open access: yesSkeletal Muscle, 2011
Myogenesis is a complex and tightly regulated process, the end result of which is the formation of a multinucleated myofibre with contractile capability.
Knight James DR, Kothary Rashmi
doaj   +1 more source

Electrical coupling between ventricular myocytes and myofibroblasts in the infarcted mouse heart [PDF]

open access: yes, 2017
Aims: Recent studies have demonstrated electrotonic coupling between scar tissue and the surrounding myocardium in cryoinjured hearts. However, the electrical dynamics occurring at the myocyte-nonmyocyte interface in the fibrotic heart remain ...
Conway, Simon J.   +6 more
core   +1 more source

Active Movement of the Tunic in Halocynthia roretzi

open access: yesJournal of Biomechanical Science and Engineering, 2010
Halocynthia roretzi, a solitary ascidian, can swell and deflate its solid, leather-like tunic largely, but it is not clear whether the tunic deforms actively.
Yoko KATO
doaj   +1 more source

Intramyocardial Fibroblast Myocyte Communication [PDF]

open access: yesCirculation Research, 2010
Abstract : Cardiac fibroblasts are emerging as key components of normal cardiac function, as well as the response to stressors and injury. These most numerous cells of the heart interact with myocytes via paracrine mechanisms, alterations in ...
Rahul, Kakkar, Richard T, Lee
openaire   +2 more sources

Sex differences in skeletal muscle revealed through fiber type, capillarity, and transcriptomics profiling in mice

open access: yesPhysiological Reports, 2021
Skeletal muscle anatomy and physiology are sexually dimorphic but molecular underpinnings and muscle‐specificity are not well‐established. Variances in metabolic health, fitness level, sedentary behavior, genetics, and age make it difficult to discern ...
Juliana O’Reilly   +7 more
doaj   +1 more source

Ghrelin Stimulates Myocyte Development [PDF]

open access: yesCellular Physiology and Biochemistry, 2007
Ghrelin, a gastric peptide hormone, may regulate mesenchymal cell development. Here we show that ghrelin promotes myogenesis in vitro in the mouse myoblast cell line C2C12 cells. Cells expressing ghrelin demonstrated a significant increase in the differentiation of premyocytes into myocytes.
Weizhen, Zhang   +2 more
openaire   +2 more sources

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