Results 121 to 130 of about 287,296 (284)

Cell typing of biological heart valves prosthesis explanated due to the development of calcium-associated dysfunctions

Бюллетень сибирской медицины, 2018
Purpose. To perform immunohistochemical typing of cells obtained from calcinated biological heart valve prosthesis removed during reoperations.Materials and methods.
R. A. Mukhamadiyarov, N. V. Rutkovskaya, S. G. Rutkovskaya, Yu. N. Odarenko, I. V. Mil’to, L. S. Barbarash   +5 more
doaj   +1 more source

The meaning of different forms of structural myocardial injury, immune response and timing of infarct necrosis and cardiac repair [PDF]

, 2015
Although a decline in the all-cause and cardiac mortality rates following myocardial infarction (MI) during the past 3 decades has been reported, MI is a major cause of death and disability worldwide.
Bello, S, Fineschi, Vittorio, Neri, M, Pomara, C, Riezzo, I, Turillazzi, E   +5 more
core   +1 more source

Increased arterial smooth muscle Ca2+ signaling, vasoconstriction, and myogenic reactivity in Milan hypertensive rats.

American Journal of Physiology. Heart and Circulatory Physiology, 2012
The Milan hypertensive strain (MHS) rats are a genetic model of hypertension with adducin gene polymorphisms linked to enhanced renal tubular Na(+) reabsorption.
Cristina I. Linde, Eiji Karashima, H. Raina, A. Zulian, W. Wier, J. Hamlyn, P. Ferrari, M. Blaustein, V. Golovina   +8 more
semanticscholar   +1 more source

Modified cytoskeletal and extracellular matrix composition in the canine testis after long‐acting gonadotropin‐releasing hormone agonist deslorelin treatment

Andrology, EarlyView.
Abstract Background Long‐acting gonadotropin‐releasing hormone (GnRH) agonists are commonly used for fertility control in male dogs. Their effect on testicular histomorphology has not been clarified. Objectives To elucidate the mechanisms underlying androgen withdrawal in response to long‐acting GnRH agonist deslorelin 4.7 mg treatment on testicular ...
Aykut Gram, Murat Abay, Duygu Yaman Gram, Narin Liman, Linda Müller, Orsolya Balogh   +5 more
wiley   +1 more source

TRPV4 Activation during Guinea Pig Airway Smooth Muscle Contraction Promotes Ca²⁺ and Na⁺ Influx

Pharmaceuticals
Airway smooth muscle (ASM) contraction is determined by the increase in intracellular Ca2+ concentration ([Ca2+]i) caused by its release from the sarcoplasmic reticulum (SR) or by extracellular Ca2+ influx.
Luis M. Montaño, Abril Carbajal-García, María F. Casas-Hernández, David Arredondo-Zamarripa, Jorge Reyes-García   +4 more
doaj   +1 more source

Double labelling immunohistochemical characterization of autonomic sympathetic neurons innervating the sow retractor clitoridis muscle

European Journal of Histochemistry, 2009
Retrograde neuronal tracing and immunohistochemical methods were used to define the neurochemical content of sympathetic neurons projecting to the sow retractor clitoridis muscle (RCM). Differently from the other smooth muscles of genital organs, the RCM
L Ragionieri, M Botti, F Gazza, L Bo Minelli, F Acone, R Panu, G Palmieri   +6 more
doaj   +1 more source

Cromakalim (BRL 34915) restores in vitro the membrane potential of depolarized human skeletal muscle fibres [PDF]

, 1989
The purpose of the present study was to analyze the effects of cromakalim (BRL 34915), a potent drug from a new class of drugs characterized as K+ channel openers, on the electrical activity of human skeletal muscle.
Grafe, Peter, Lehmann-Horn, Frank, Spuler, A.   +2 more
core   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

TRPV4-Like Non-selective Cation Currents in Cultured Aortic Myocytes

Journal of Pharmacological Sciences, 2008
In this study, we provide evidence of critical changes in the expression of non-selective cation currents (NSCC) during culture in rat aortic myocytes.
Ryoichi Tanaka, Katsuhiko Muraki, Susumu Ohya, Hisao Yamamura, Noriyuki Hatano, Yuka Itoh, Yuji Imaizumi   +6 more
doaj  

Role of Histone Deacetylase and Inhibitors in Cardiovascular Diseases

Cell Proliferation, EarlyView.
HDACs play an important role in the occurrence and development of cardiovascular diseases, such as myocardial hypertrophy, hypertension, and atherosclerosis. HDAC inhibitors have broad prospects for the treatment of CVD, and different HDAC subtypes can act through different mechanisms.
Li‐Ying Zhang, Yue‐Yue Wang, Ri Wen, Tie‐Ning Zhang, Ni Yang   +4 more
wiley   +1 more source