Results 171 to 180 of about 35,109 (214)
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Myocyte Enhancer Binding Factor-2 Expression and Activity in Vascular Smooth Muscle Cells
Circulation Research, 1996Abstract Proliferation and phenotypic modulation of smooth muscle cells (SMCs) are major components of the vessel’s response to injury in experimental models of restenosis. Some of the growth factors involved in restenosis have been identified, but to date little is known about the transcription factors that ultimately regulate
A B, Firulli +6 more
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Cell Biochemistry and Function, 2011
The genetic basis for the phenotypic switching of vascular smooth muscle cells (VSMCs) is unclear in atherosclerosis. Recent studies showed that the 21‐base pair deletion mutation (Δ21) in myocyte enhancer factor 2A (MEF2A) gene could be an inherited marker for coronary artery disease. MEF2A mutation may affect the phenotypic switching of VSMCs.
Wang, Zhao +2 more
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The genetic basis for the phenotypic switching of vascular smooth muscle cells (VSMCs) is unclear in atherosclerosis. Recent studies showed that the 21‐base pair deletion mutation (Δ21) in myocyte enhancer factor 2A (MEF2A) gene could be an inherited marker for coronary artery disease. MEF2A mutation may affect the phenotypic switching of VSMCs.
Wang, Zhao +2 more
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genesis, 2005
The cytoskeletal protein SM22alpha is expressed in visceral and vascular smooth muscle cells (SMCs), in cardiac myocytes, and in the myotomal components of the somites during murine embryonic development. In this report, we describe the generation and characterization of transgenic mice expressing Cre-recombinase under the transcriptional control of ...
John J, Lepore +5 more
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The cytoskeletal protein SM22alpha is expressed in visceral and vascular smooth muscle cells (SMCs), in cardiac myocytes, and in the myotomal components of the somites during murine embryonic development. In this report, we describe the generation and characterization of transgenic mice expressing Cre-recombinase under the transcriptional control of ...
John J, Lepore +5 more
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Current Opinion in Nephrology and Hypertension, 1993
Structural changes of the heart and blood vessels participate in the long-term regulation of the cardiovascular system. In hypertension and myocardial dysfunction, the adaptive process of cardiac and vascular remodeling may contribute to the pathophysiology and complications of these diseases.
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Structural changes of the heart and blood vessels participate in the long-term regulation of the cardiovascular system. In hypertension and myocardial dysfunction, the adaptive process of cardiac and vascular remodeling may contribute to the pathophysiology and complications of these diseases.
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Membrane Actions of Calcitonin Gene‐Related Peptide in Cardiac and Smooth Muscle Myocytesa
Annals of the New York Academy of Sciences, 1992Calcitonin gene-related peptide is a 37-amino acid neuropeptide acting as a transmitter of nonadrenergic, noncholinergic nerves in the heart. Binding sites of high affinity have been reported in coronary arteries, in atria, and, of minor density, in ventricular myocardium.
H A, Tritthart +5 more
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Molecular and Cellular Biochemistry, 1991
Previous reports have confirmed that steroid hormones modulate the expression of adrenergic receptors on the surface of smooth muscle myocytes. The present study was undertaken to evaluate the mechanism by which testosterone modulates alpha-1 adrenergic receptor expression in the DDT1 MF-2 transformed smooth muscle cell.
M, Phillippe, T, Saunders, S, Bangalore
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Previous reports have confirmed that steroid hormones modulate the expression of adrenergic receptors on the surface of smooth muscle myocytes. The present study was undertaken to evaluate the mechanism by which testosterone modulates alpha-1 adrenergic receptor expression in the DDT1 MF-2 transformed smooth muscle cell.
M, Phillippe, T, Saunders, S, Bangalore
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Morfologiia (Saint Petersburg, Russia), 1998
Comparative analysis of smooth muscular tissue of bronchi and of rectal pelvic region was performed using electron microscopic and cytophotometric methods. Smooth myocyte population of organs studied were demonstrated to include three cell types: small, medium and large ones.
A L, Zashikhin, Iu V, Agafonov
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Comparative analysis of smooth muscular tissue of bronchi and of rectal pelvic region was performed using electron microscopic and cytophotometric methods. Smooth myocyte population of organs studied were demonstrated to include three cell types: small, medium and large ones.
A L, Zashikhin, Iu V, Agafonov
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Thrombosis and Haemostasis, 1999
SummaryTissue factor pathway inhibitor (TFPI) plays an important role in regulating tissue factor (TF)-initiated blood coagulation. Since serum stimulation of fibroblasts, vascular smooth muscle cells and cardiac myocytes in culture increases the expression of TF mRNA and antigen (Ag) in these cells, we hypothesized that serum may also induce increased
M S, Bajaj +4 more
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SummaryTissue factor pathway inhibitor (TFPI) plays an important role in regulating tissue factor (TF)-initiated blood coagulation. Since serum stimulation of fibroblasts, vascular smooth muscle cells and cardiac myocytes in culture increases the expression of TF mRNA and antigen (Ag) in these cells, we hypothesized that serum may also induce increased
M S, Bajaj +4 more
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Journal of Molecular and Cellular Cardiology, 1996
Transforming growth factor-beta 1 (TGF-beta 1) is known to regulate cardiac cell function and its overexpression in the heart is thought to contribute to the development of cardiac hypertrophy and fibrosis. We wished to develop a high efficiency gene transfer method that could be used both in vitro and in vivo and result in the overexpression of TGF ...
F J, Villarreal +3 more
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Transforming growth factor-beta 1 (TGF-beta 1) is known to regulate cardiac cell function and its overexpression in the heart is thought to contribute to the development of cardiac hypertrophy and fibrosis. We wished to develop a high efficiency gene transfer method that could be used both in vitro and in vivo and result in the overexpression of TGF ...
F J, Villarreal +3 more
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[Myocyte transformation in autologous transplantation of colonic smooth muscle in domestic pigs].
Ceskoslovenska patologie, 1994Autologous gut smooth muscle graft of two piglets was used for creating a ring in sigmoidostomy. The graft was investigated several times by histology and electron microscopy. A sort of myofibroblasts were observed the 7th day in the smooth muscle.
M, Tichý +3 more
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