Results 181 to 190 of about 35,109 (214)
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Hypertension Differentially Affects the Expression of the Gap Junction Protein Connexin43 in Cardiac Myocytes and Aortic Smooth Muscle Cells

1997
Electrical and mechanical coupling of myocytes in heart and of smooth muscle cells in the aortic wall is thought to be mediated by intercellular channels aggregated at gap junctions. Connexin43 (Cx43) is one of the predominant membrane proteins forming junctional channels in the cardiovascular system.
Haefliger JA   +6 more
openaire   +3 more sources

Myocyte Enhancer Factor 2A Regulates Hydrogen Peroxide‐Induced Senescence of Vascular Smooth Muscle Cells Via microRNA‐143

Journal of Cellular Physiology, 2015
Myocyte enhancer factor 2A (MEF2A) is involved in vascular smooth muscle cell (VSMC) proliferation, migration, and senescence. MicroRNA‐143/145 (miR‐143/145), which may be regulated by MEF2A, is known to promote cellular senescence. We hypothesized that MEF2A may promote VSMC senescence via miR‐143/145. VSMC senescence was induced by hydrogen peroxide (
Wang, Zhao   +3 more
openaire   +2 more sources

Overexpression of human Hsp27 inhibits serum-induced proliferation in airway smooth muscle myocytes and confers resistance to hydrogen peroxide cytotoxicity

American Journal of Physiology-Lung Cellular and Molecular Physiology, 2007
Airway smooth muscle (ASM) hypertrophy and hyperplasia are characteristics of asthma that lead to thickening of the airway wall and obstruction of airflow. Very little is known about mechanisms underlying ASM remodeling, but in vascular smooth muscle, it is known that progression of atherosclerosis depends on the balance of myocyte proliferation and ...
Sonemany, Salinthone   +5 more
openaire   +2 more sources

Abstract 1505: Sunitinib-Induced Cardiotoxicity is Mediated in Part via Direct Effects on Cardiac Myocytes and Smooth Muscle Cells

Circulation, 2007
Tyrosine kinase inhibitors (TKI) have revolutionized cancer therapy, spawning over 500 clinical trials, yet cardiotoxicities are emerging. Sunitinib, a multi-targeted TKI, prolongs life in renal cell and gastrointestinal cancer patients, but hypertension and heart failure have required treatment adjustments. Objective:
Susan M Dallabrida   +9 more
openaire   +1 more source

Leiomyoblastoma of the uterus: an immunohistochemical and electron microscopic study of distinctive tumours with immature smooth muscle cell differentiation mimicking fetal uterine myocytes

Histopathology, 2003
Aims:  We present three distinctive uterine tumours which exhibited immature smooth muscle differentiation mimicking smooth muscle cells of the fetal uterus.Methods and results:  The patients were 45, 46 and 49 years old, and all of them had simple hysterectomies.
K, Watanabe, G, Ogura, T, Suzuki
openaire   +2 more sources

Early intracellular signaling events induced by in vitro metreleptin administration in cardiac myocytes and uterine smooth muscle cells.

Cellular and molecular biology (Noisy-le-Grand, France), 2016
Intracellular signaling pathways regulated by leptin have largely been studied in metabolically important organs such as adipose tissue and peripheral blood mononuclear cells, suggesting that leptin plays a key role in pathophysiology of insulin resistance.
S K, Choi, S, Park, Y, Choi, H-S, Moon
openaire   +1 more source

Smooth Muscle Myocyte Ultrastructure and Contractility

2012
Avril V. Somlyo, Marion J. Siegman
openaire   +1 more source

Myocyte Recruitment Contributes to the Concentration-Dependence of Contractions in Airway Smooth Muscle.

D98. SMOOTH MUSCLE CONTRACTION REVEALS ITS SECRETS, 2009
S Salyk, LJ Janssen
openaire   +1 more source

Calcium phosphate coprecipitation greatly enhances transduction of cardiac myocytes and vascular smooth muscle cells by lentivirus vectors.

Experimental and clinical cardiology, 2011
Lentivirus vectors provide a delivery system that can both transduce nondividing cells and integrate transgenes into the genome of target cells without cytotoxicity. However, their relatively low transduction efficiency presents a significant obstacle to progress.In the present paper, a simple and easy method using calcium phosphate (CaPi) to enhance ...
Tsuyoshi, Sakoda   +3 more
openaire   +1 more source

80 DISEASE OF GASTROINTESTINAL SMOOTH MUSCLE INCREASES CHAOTIC MYOCYTE BEHAVIOUR

Journal of Pediatric Gastroenterology and Nutrition, 1992
W M Bisset   +3 more
openaire   +1 more source

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