Results 201 to 210 of about 36,191 (258)

The Cardiac Circadian Clock Regulates Rhythms in Peripheral Tissues via Fibulin 5. [PDF]

open access: yesCompr Physiol
Bettadapura SS   +9 more
europepmc   +1 more source

Use of cultured airway myocytes for study of airway smooth muscle

open access: yesAmerican Journal of Physiology-Lung Cellular and Molecular Physiology, 1995
Cultured airway smooth muscle cells provide a convenient model system for studying the regulation of a wide range of airway responses at the cellular level. This review describes the characteristics of cultured airway smooth muscle cells and differences that exist between cultured cells and acutely dissociated cells or muscle strips.
I P, Hall, M, Kotlikoff
openaire   +3 more sources

Distribution of phenotypically disparate myocyte subpopulations in airway smooth muscle

open access: yesCanadian Journal of Physiology and Pharmacology, 2005
Phenotype and functional heterogeneity of airway smooth muscle (ASM) cells in vitro is well known, but there is limited understanding of these features in vivo. We tested whether ASM is composed of myocyte subsets differing in contractile phenotype marker expression. We used flow cytometry to compare smooth muscle myosin heavy chain (smMHC) and smooth
Halayko, AJ   +5 more
openaire   +4 more sources

Responses of subcultured rat aortic smooth muscle myocytes to vasoactive agents and KCl-induced depolarization

open access: yesAmerican Journal of Physiology-Cell Physiology, 1991
We have developed a culture system in which a single-mass primary culture can be used for as long as 6 wk as a source of subcultured smooth muscle myocytes for the study of the changes of their shape upon addition of vasoactive agents (angiotensin, vasopressin, norepinephrine, and serotonin) and KCl depolarization.
P, Bodin   +6 more
openaire   +3 more sources
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Inactivation of Calcium Channels in Vascular Smooth Muscle Myocytes

Cell Biochemistry and Biophysics, 2006
Many of the structural domains involved in Ca2+ channel (CACN) inactivation are also involved in determining their sensitivity to antagonist inhibition. We hypothesize that differences in inactivation properties and their structural determinants may suggest candidate domains as targets for the development of novel, selective antagonists.
Robert H, Cox, Martin, Kathrins
openaire   +2 more sources

The contractile strength of vascular smooth muscle myocytes is shape dependent

Integrative Biology, 2014
Vascular smooth muscle cells in muscular arteries are more elongated than those in elastic arteries. Previously, we reported changes in the contractility of engineered vascular smooth muscle tissue that appeared to be correlated with the shape of the constituent cells, supporting the commonly held belief that elongated muscle geometry may allow for the
Ye G. J. C.   +5 more
openaire   +3 more sources

Adrenergic stimulation of diacylglycerol production in genital tract smooth muscle myocytes

In Vitro Cellular & Developmental Biology - Animal, 1993
Diacylglycerol (DAG) production has not been reported in previous studies that have characterized inositol phosphate production during alpha-1 adrenergic receptor signal transduction in the DDT1 MF-2 genital tract myocytes. The current study sought to measure norepinephrine (NE)-stimulated DAG production in these transformed myocytes utilizing thin ...
R J, Austin, L, DiGiovonni, M, Phillippe
openaire   +3 more sources

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