Results 11 to 20 of about 35,109 (214)
The World Journal of Men's Health, 2023 Purpose: We aimed to investigate the mechanism of phenotypic transformation of corporal cavernosum smooth muscle cells (CCSMCs) under hypoxic conditions in vitro.
Xiongcai Zhou +6 more
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Scientific Reports, 2023 Cell-based therapy is a major focus for treatment of stress urinary incontinence (SUI). However, derivation of primary cells requires tissue biopsies, which often have adverse effects on patients. A recent study used human induced pluripotent stem cells (
M. Kibschull +6 more
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Arterial smooth muscle cell PKD2 (TRPP1) channels regulate systemic blood pressure
eLife, 2018 Systemic blood pressure is determined, in part, by arterial smooth muscle cells (myocytes). Several Transient Receptor Potential (TRP) channels are proposed to be expressed in arterial myocytes, but it is unclear if these proteins control physiological ...
Simon Bulley +12 more
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Proliferative Role of Kv11 Channels in Murine Arteries
Frontiers in Physiology, 2017 K+ channels encoded by the ether-a-go-go related gene (ERG1 or KCNH2) are important determinants of the cardiac action potential. Expression of both cardiac isoforms (ERG1a and ERG1b) were identified in murine portal vein and distinctive voltage-gated K+
Vincenzo Barrese +7 more
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Divergent differentiation paths in airway smooth muscle culture: induction of functionally contractile myocytes [PDF]
American Journal of Physiology-Lung Cellular and Molecular Physiology, 1999 We tested the hypothesis that prolonged serum deprivation would allow a subset of cultured airway myocytes to reacquire the abundant contractile protein content, marked shortening capacity, and elongated morphology characteristic of contractile cells within intact tissue. Passage 1 or 2 canine tracheal smooth muscle (SM) cells were grown to confluence,
A J, Halayko +7 more
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Mitochondrial Modulation Of Spontaneous Ca2+ Oscillations In Portal Vein Smooth Muscle Myocytes [PDF]
Biophysical Journal, 2009 Transient increases in cytosolic Ca2+ concentration ([Ca2+]c) regulate many smooth muscle activities including contraction, transcription, growth and apoptosis. The onset of some processes involve sarcoplasmic reticulum Ca2+ release triggered by either inositol 1,4,5-trisphosphate (InsP3) or occurring spontaneously. Mitochondrial Ca2+ uptake influences
Olson, Marnie L. +5 more
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Reproductive Biology and Endocrinology, 2008 Background Myometrial smooth myocytes contract as a result of electrical signalling via a process called excitation-contraction coupling. This process is understood in great detail at the cellular level but the generation and coordination of electrical ...
Van Lommel Alfons +6 more
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Journal of Pharmacological Sciences, 2006 .: In mouse intestinal smooth muscle cells held at −50 mV, carbachol evoked an atropine-sensitive inward current in the intracellular presence of Cs+.
Takashi Sakamoto +6 more
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The use of calcium channel blockers in the treatment of cardiovascular diseases [PDF]
Arhiv za farmaciju, 2015 Voltage-sensitive calcium channels (L-type) mediate the entry of extracellular calcium into smooth muscle and cardiac myocytes and sinoatrial and atrioventricular nodal cells in response to electrical depolarization.
Đokić Mirjana
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LIM-only protein, CRP2, switched on smooth muscle gene activity in adult cardiac myocytes [PDF]
Proceedings of the National Academy of Sciences, 2007 Smooth muscle α-actin gene activity appears in promyocardial cells well before cardiac myocyte differentiation and is down-regulated during the onset of rhythmic contractility and cardiac morphogenesis. The levels of LIM-only CRP2 correlated well with smooth muscle gene activity.
David F, Chang +3 more
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