Results 31 to 40 of about 36,191 (258)

Calcium currents in isolated rabbit coronary arterial smooth muscle myocytes.

The Journal of Physiology, 1990
1. Calcium inward currents were recorded from relaxed enzymatically isolated smooth muscle cells from the rabbit epicardial left descending coronary artery using a single‐pipette voltage‐clamp technique. Outward K+ currents were blocked with CsCl‐tetraethylammonium‐filled pipette solutions. 2. Relaxed coronary smooth muscle cells had a maximum diameter
J J, Matsuda, K A, Volk, E F, Shibata
openaire   +3 more sources

Piezo1 in Smooth Muscle Cells Is Involved in Hypertension-Dependent Arterial Remodeling

Cell Reports, 2015
The mechanically activated non-selective cation channel Piezo1 is a determinant of vascular architecture during early development. Piezo1-deficient embryos die at midgestation with disorganized blood vessels.
Kevin Retailleau, Fabrice Duprat, Malika Arhatte, Sanjeev Sumant Ranade, Rémi Peyronnet, Joana Raquel Martins, Martine Jodar, Céline Moro, Stefan Offermanns, Yuanyi Feng, Sophie Demolombe, Amanda Patel, Eric Honoré   +12 more
doaj   +1 more source

Effects of polyamines on the muscarinic receptor‐operated cation current in guinea‐pig ileal smooth muscle myocytes [PDF]

British Journal of Pharmacology, 2004
The effects of extracellular and intracellular polyamines (PAs), spermine and putrescine, on the cation current (mICAT) evoked either by activating muscarinic receptors with carbachol or by intracellularly applied GTPγS (in the absence of carbachol) were studied using patch‐clamp recording techniques in single guinea‐pig ileal myocytes. Extracellular
Tsvilovskyy, V.V., Zholos, Alexander, Bolton, T.B.   +2 more
openaire   +2 more sources

Validation of XE991 use as a Selective Irreversible Blocker of Native Kv7 Channels in Smooth Muscle Myocytes [PDF]

Biophysical Journal, 2012
A concern was recently raised about the selectivity of XE991 and its use as a Kv7 channel blocker in single cell electrophysiology and in vitro functional assays. In the present study, we evaluated the effects of XE991 on different components of the endogenous delayed rectifier potassium currents recorded in freshly isolated guinea pig airway myocytes ...
Brueggemann, Lyubov I., Byron, Kenneth L.   +1 more
openaire   +1 more source

Enhancement of K+ conductance improves in vitro the contraction force of skeletal muscle in hypokalemic periodic paralysis [PDF]

, 1990
An abnormal ratio between Na+ and K+ conductances seems to be the cause for the depolarization and paralysis of skeletal muscle in primary hypokalemic periodic paralysis.
Quasthoff, Stefan, Lehmann-Horn, Frank, Strupp, Michael, Grafe, Peter   +3 more
core   +1 more source

Endothelin-Induced Sarcoplasmic Reticulum Calcium Depletion Waves in Vascular Smooth Muscle Cells

, 2011
Agonist-stimulated waves of elevated cytoplasmic Ca2+ concentration ([Ca2+]i ) regulate blood vessel tone and vasomotion in vascular smooth muscle. Previous studies employing cytoplasmic Ca2+ indicators revealed that these Ca2+ waves were generated by a ...
Cornelis van Breemen, Jeremy Hoskins, Arash Y. Tehrani, Mitra Esfandiarei, Yohan Choi, Nicola Fameli, Jeremy G. Hoskins, Arash Tehrani   +7 more
core   +1 more source

Characterization of the tissue-level Ca2+signals in spontaneously contracting human myometrium [PDF]

, 2012
In the labouring uterus, millions of myocytes forming the complex geometrical structure of myometrium contract in synchrony to increase intrauterine pressure, dilate the cervix and eventually expel the foetus through the birth canal.
Blanks, Andrew M., Thornton, S, Blanks, AM, Gullam, Joanna E., Thornton, Steven, Shmygol, A, Gullam, JE, Bru-Mercier, Gilles, Shmygol, Anatoly, Bru-Mercier, G   +9 more
core   +1 more source

Two isoforms of Trpm8 in rat vas deferens

Біологічні студії, 2019
Trpm8 is a nonselective Ca2+-permeable ion channel activated by temperatures below 28 °C and cooling chemical compounds such as menthol and icilin. Trpm8 is expressed in sensory neurons where it functions for temperature detection. However, Trpm8 is also
K. Gulak, A. Kondratskyi
doaj   +1 more source

Muller Muscle of the Upper Eyelid: Histopathological Features of Congenital and Acquired Ptosis

Oftalʹmologiâ, 2020
Purpose: to study the histological features of the Muller muscle of the upper eyelid in patients with congenital and acquired ptosis to understand the mechanism of ptosis. Material and methods.
M. G. Kataev, A. V. Shatskikh, M. A. Zaharova, Z. R. Dzagurova, A. V. Shahmatova, N. M. Kataeva   +5 more
doaj   +1 more source

Suppression of cardiomyocyte functions by β-CTX isolated from the Thai king cobra (Ophiophagus hannah) venom via an alternative method [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases, 2020
Background: Beta-cardiotoxin (β-CTX), the three-finger toxin isolated from king cobra (Ophiophagus hannah) venom, possesses β-blocker activity as indicated by its negative chronotropy and its binding property to both β-1 and β-2 adrenergic receptors and ...
Tuchakorn Lertwanakarn, Montamas Suntravat, Elda E. Sanchez, Worakan Boonhoh, R. John Solaro, Beata M. Wolska, Jody L. Martin, Pieter P. de Tombe, Kittipong Tachampa   +8 more
doaj   +1 more source