Results 31 to 40 of about 1,322,246 (257)
Inhibition of native TRPC6 channel activity by phosphatidylinositol 4,5-bisphosphate in mesenteric artery myocytes [PDF]
, 2008 The present work investigates the effect of phosphatidylinositol-4,5-bisphosphate (PIP2) on native TRPC6 channel activity in freshly dispersed rabbit mesenteric artery myocytes using patch clamp recording and co-immunoprecipitation methods.
Saleh, Sohag N. +5 more
core +1 more source
PLoS ONE, 2008 BackgroundHollow smooth muscle organs such as the bladder undergo significant changes in wall tension associated with filling and distension, with attendant changes in muscle tone.
Bin Wei +9 more
doaj +1 more source
Arquivos Brasileiros de Cardiologia, 1999 OBJECTIVE: To study the healing process of the myocardium in hypertensive rats undergoing inhibition of nitric oxide synthesis. METHODS: Two groups of animals were studied: one received L-NAME, 12mg/kg/day, and the other was a control group. The presence
Mônica Gomes Pessanha +2 more
doaj +1 more source
Calix[4]arene C-99 inhibits myosin ATPase activity and changes the organization of contractile filaments of myometrium [PDF]
The Ukrainian Biochemical Journal, 2015 Calix[4]arenes are cup-like macrocyclic (polyphenolic) compounds, they are regarded as promising molecular “platforms” for the design of new physiologically active compounds.
R. D. Labyntseva, +5 more
doaj +1 more source
Calcium currents in isolated rabbit coronary arterial smooth muscle myocytes.
The Journal of Physiology, 1990 1. Calcium inward currents were recorded from relaxed enzymatically isolated smooth muscle cells from the rabbit epicardial left descending coronary artery using a single‐pipette voltage‐clamp technique. Outward K+ currents were blocked with CsCl‐tetraethylammonium‐filled pipette solutions. 2. Relaxed coronary smooth muscle cells had a maximum diameter
J J, Matsuda, K A, Volk, E F, Shibata
openaire +3 more sources
Frontiers in Physiology, 2020 Smooth muscle cells of the vasculature, viscera, and lungs generally express multiple α-subunits of the Kv7 voltage-gated potassium channel family, with increasing evidence that both Kv7.4 and Kv7.5 can conduct “M-currents” that are functionally ...
Lyubov I. Brueggemann +2 more
doaj +1 more source
Kv7 and Kv11 channels in myometrial regulation. [PDF]
, 2013 Ion channels play a key role in defining myometrial contractility. Modulation of ion channel populations is proposed to underpin gestational changes in uterine contractility associated with the transition from uterine quiescence to active labour.
Tribe, Rachel M; id_orcid +5 more
core +1 more source
Piezo1 in Smooth Muscle Cells Is Involved in Hypertension-Dependent Arterial Remodeling
Cell Reports, 2015 The mechanically activated non-selective cation channel Piezo1 is a determinant of vascular architecture during early development. Piezo1-deficient embryos die at midgestation with disorganized blood vessels.
Kevin Retailleau +12 more
doaj +1 more source
Effects of polyamines on the muscarinic receptor‐operated cation current in guinea‐pig ileal smooth muscle myocytes [PDF]
British Journal of Pharmacology, 2004 The effects of extracellular and intracellular polyamines (PAs), spermine and putrescine, on the cation current (mICAT) evoked either by activating muscarinic receptors with carbachol or by intracellularly applied GTPγS (in the absence of carbachol) were studied using patch‐clamp recording techniques in single guinea‐pig ileal myocytes. Extracellular
Tsvilovskyy, V.V. +2 more
openaire +2 more sources
Endothelins. Myocardial actions of a new class of cytokines [PDF]
, 1992 There is growing evidence to support the existence of a dynamic interaction in vivo between cardiac myocytes and adjacent microvascular endothelial cells in the regulation of both cardiac myocyte and possibly endothelial cell phenotype and function ...
Smith, T. W. +3 more
core +1 more source