Results 221 to 230 of about 62,427 (259)
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Biochemical Journal, 2000
We have identified a new cyclic-nucleotide phosphodiesterase isoform, PDE3A, and cloned its cDNA from cultured aortic myocytes. The nucleotide sequence of its coding region is similar to that of the previously cloned myocardial isoform except for the absence of the initial 300–400nt that are present in the latter, as confirmed by reverse-transcriptase ...
Y H, Choi +6 more
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We have identified a new cyclic-nucleotide phosphodiesterase isoform, PDE3A, and cloned its cDNA from cultured aortic myocytes. The nucleotide sequence of its coding region is similar to that of the previously cloned myocardial isoform except for the absence of the initial 300–400nt that are present in the latter, as confirmed by reverse-transcriptase ...
Y H, Choi +6 more
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Journal of Cellular Physiology, 2015
Myocyte enhancer factor 2A (MEF2A) is involved in vascular smooth muscle cell (VSMC) proliferation, migration, and senescence. MicroRNA‐143/145 (miR‐143/145), which may be regulated by MEF2A, is known to promote cellular senescence. We hypothesized that MEF2A may promote VSMC senescence via miR‐143/145. VSMC senescence was induced by hydrogen peroxide (
Wang, Zhao +3 more
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Myocyte enhancer factor 2A (MEF2A) is involved in vascular smooth muscle cell (VSMC) proliferation, migration, and senescence. MicroRNA‐143/145 (miR‐143/145), which may be regulated by MEF2A, is known to promote cellular senescence. We hypothesized that MEF2A may promote VSMC senescence via miR‐143/145. VSMC senescence was induced by hydrogen peroxide (
Wang, Zhao +3 more
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Membrane Actions of Calcitonin Gene‐Related Peptide in Cardiac and Smooth Muscle Myocytesa
Annals of the New York Academy of Sciences, 1992Calcitonin gene-related peptide is a 37-amino acid neuropeptide acting as a transmitter of nonadrenergic, noncholinergic nerves in the heart. Binding sites of high affinity have been reported in coronary arteries, in atria, and, of minor density, in ventricular myocardium.
H A, Tritthart +5 more
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Journal of Molecular and Cellular Cardiology, 1996
Transforming growth factor-beta 1 (TGF-beta 1) is known to regulate cardiac cell function and its overexpression in the heart is thought to contribute to the development of cardiac hypertrophy and fibrosis. We wished to develop a high efficiency gene transfer method that could be used both in vitro and in vivo and result in the overexpression of TGF ...
F J, Villarreal +3 more
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Transforming growth factor-beta 1 (TGF-beta 1) is known to regulate cardiac cell function and its overexpression in the heart is thought to contribute to the development of cardiac hypertrophy and fibrosis. We wished to develop a high efficiency gene transfer method that could be used both in vitro and in vivo and result in the overexpression of TGF ...
F J, Villarreal +3 more
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Cell Biochemistry and Function, 2011
The genetic basis for the phenotypic switching of vascular smooth muscle cells (VSMCs) is unclear in atherosclerosis. Recent studies showed that the 21‐base pair deletion mutation (Δ21) in myocyte enhancer factor 2A (MEF2A) gene could be an inherited marker for coronary artery disease. MEF2A mutation may affect the phenotypic switching of VSMCs.
Wang, Zhao +2 more
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The genetic basis for the phenotypic switching of vascular smooth muscle cells (VSMCs) is unclear in atherosclerosis. Recent studies showed that the 21‐base pair deletion mutation (Δ21) in myocyte enhancer factor 2A (MEF2A) gene could be an inherited marker for coronary artery disease. MEF2A mutation may affect the phenotypic switching of VSMCs.
Wang, Zhao +2 more
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Molecular and Cellular Biochemistry, 1991
Previous reports have confirmed that steroid hormones modulate the expression of adrenergic receptors on the surface of smooth muscle myocytes. The present study was undertaken to evaluate the mechanism by which testosterone modulates alpha-1 adrenergic receptor expression in the DDT1 MF-2 transformed smooth muscle cell.
M, Phillippe, T, Saunders, S, Bangalore
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Previous reports have confirmed that steroid hormones modulate the expression of adrenergic receptors on the surface of smooth muscle myocytes. The present study was undertaken to evaluate the mechanism by which testosterone modulates alpha-1 adrenergic receptor expression in the DDT1 MF-2 transformed smooth muscle cell.
M, Phillippe, T, Saunders, S, Bangalore
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[Myocyte transformation in autologous transplantation of colonic smooth muscle in domestic pigs].
Ceskoslovenska patologie, 1994Autologous gut smooth muscle graft of two piglets was used for creating a ring in sigmoidostomy. The graft was investigated several times by histology and electron microscopy. A sort of myofibroblasts were observed the 7th day in the smooth muscle.
M, Tichý +3 more
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Thrombosis and Haemostasis, 1999
SummaryTissue factor pathway inhibitor (TFPI) plays an important role in regulating tissue factor (TF)-initiated blood coagulation. Since serum stimulation of fibroblasts, vascular smooth muscle cells and cardiac myocytes in culture increases the expression of TF mRNA and antigen (Ag) in these cells, we hypothesized that serum may also induce increased
M S, Bajaj +4 more
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SummaryTissue factor pathway inhibitor (TFPI) plays an important role in regulating tissue factor (TF)-initiated blood coagulation. Since serum stimulation of fibroblasts, vascular smooth muscle cells and cardiac myocytes in culture increases the expression of TF mRNA and antigen (Ag) in these cells, we hypothesized that serum may also induce increased
M S, Bajaj +4 more
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American Journal of Physiology-Lung Cellular and Molecular Physiology, 2007
Airway smooth muscle (ASM) hypertrophy and hyperplasia are characteristics of asthma that lead to thickening of the airway wall and obstruction of airflow. Very little is known about mechanisms underlying ASM remodeling, but in vascular smooth muscle, it is known that progression of atherosclerosis depends on the balance of myocyte proliferation and ...
Sonemany, Salinthone +5 more
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Airway smooth muscle (ASM) hypertrophy and hyperplasia are characteristics of asthma that lead to thickening of the airway wall and obstruction of airflow. Very little is known about mechanisms underlying ASM remodeling, but in vascular smooth muscle, it is known that progression of atherosclerosis depends on the balance of myocyte proliferation and ...
Sonemany, Salinthone +5 more
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Morfologiia (Saint Petersburg, Russia), 1998
Comparative analysis of smooth muscular tissue of bronchi and of rectal pelvic region was performed using electron microscopic and cytophotometric methods. Smooth myocyte population of organs studied were demonstrated to include three cell types: small, medium and large ones.
A L, Zashikhin, Iu V, Agafonov
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Comparative analysis of smooth muscular tissue of bronchi and of rectal pelvic region was performed using electron microscopic and cytophotometric methods. Smooth myocyte population of organs studied were demonstrated to include three cell types: small, medium and large ones.
A L, Zashikhin, Iu V, Agafonov
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