Results 21 to 30 of about 285,913 (271)
Nitric oxide mediates stretch-induced Ca2+ release via activation of phosphatidylinositol 3-kinase-Akt pathway in smooth muscle. [PDF]
PLoS ONE, 2008 Hollow smooth muscle organs such as the bladder undergo significant changes in wall tension associated with filling and distension, with attendant changes in muscle tone. Our previous study indicated that stretch induces Ca(2+) release occurs in the form
Bin Wei +9 more
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Biochemical and molecular-physiological aspects of the nitric oxide action in the utera [PDF]
The Ukrainian Biochemical Journal, 2021 The sources of the nitric oxide (NO) formation in the uterus and the dynamics of changes in its content in different periods of organ functioning in human and animals are analyzed.
H. V. Danylovych, Yu. V. Danylovych
doaj +1 more source
Immunocytochemical characteristics of submucosal uterine myomas [PDF]
Vojnosanitetski Pregled, 2010 Background/Aim. Myomas of the uterus, the most common benign tumors, have been studied for decades from the aspects of different basic and clinical disciplines. Despite this fact, their pathogenesis is still poorly understood.
Mladenović-Mihailović Aleksandra +5 more
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Key role for Kv11.1 (ether‐a‐go‐go related gene) channels in rat bladder contractility
Physiological Reports, 2023 In addition, to their established role in cardiac myocytes and neurons, ion channels encoded by ether‐a‐go‐go‐related genes (ERG1‐3 or kcnh2,3 and 6) (kcnh2) are functionally relevant in phasic smooth muscle.
Vincenzo Barrese +7 more
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The World Journal of Men's Health, 2023 Purpose: We aimed to investigate the mechanism of phenotypic transformation of corporal cavernosum smooth muscle cells (CCSMCs) under hypoxic conditions in vitro.
Xiongcai Zhou +6 more
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Scientific Reports, 2023 Cell-based therapy is a major focus for treatment of stress urinary incontinence (SUI). However, derivation of primary cells requires tissue biopsies, which often have adverse effects on patients. A recent study used human induced pluripotent stem cells (
M. Kibschull +6 more
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A computational model predicts sex-specific responses to calcium channel blockers in mammalian mesenteric vascular smooth muscle. [PDF]
ElifeThe function of the smooth muscle cells lining the walls of mammalian systemic arteries and arterioles is to regulate the diameter of the vessels to control blood flow and blood pressure. Here, we describe an in silico model, which we call the ‘Hernandez–
Hernandez-Hernandez G +8 more
europepmc +2 more sources
Stretch-induced Calcium Release in Smooth Muscle [PDF]
, 2002 Smooth muscle cells undergo substantial increases in length, passively stretching during increases in intraluminal pressure in vessels and hollow organs. Active contractile responses to counteract increased transmural pressure were first described almost
Barsotti, Robert J. +3 more
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The use of calcium channel blockers in the treatment of cardiovascular diseases [PDF]
Arhiv za farmaciju, 2015 Voltage-sensitive calcium channels (L-type) mediate the entry of extracellular calcium into smooth muscle and cardiac myocytes and sinoatrial and atrioventricular nodal cells in response to electrical depolarization.
Đokić Mirjana
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Validation of XE991 use as a Selective Irreversible Blocker of Native Kv7 Channels in Smooth Muscle Myocytes [PDF]
Biophysical Journal, 2012 A concern was recently raised about the selectivity of XE991 and its use as a Kv7 channel blocker in single cell electrophysiology and in vitro functional assays. In the present study, we evaluated the effects of XE991 on different components of the endogenous delayed rectifier potassium currents recorded in freshly isolated guinea pig airway myocytes ...
Lyubov I. Brueggemann, Kenneth L. Byron
openaire +2 more sources