LSD1 Controls Timely MyoD Expression via MyoD Core Enhancer Transcription [PDF]
Cell Reports, 2017 MyoD is a master regulator of myogenesis. Chromatin modifications required to trigger MyoD expression are still poorly described. Here, we demonstrate that the histone demethylase LSD1/KDM1a is recruited on the MyoD core enhancer upon muscle ...
Shinichiro Hayashi +2 more
exaly +7 more sources
The requirement of Mettl3-promoted MyoD mRNA maintenance in proliferative myoblasts for skeletal muscle differentiation [PDF]
Open Biology, 2017 Myogenic progenitor/stem cells retain their skeletal muscle differentiation potential by maintaining myogenic transcription factors such as MyoD. However, the mechanism of how MyoD expression is maintained in proliferative progenitor cells has not been ...
Kensuke Kudou +2 more
exaly +2 more sources
Loss of MyoD Promotes Fate Transdifferentiation of Myoblasts Into Brown Adipocytes
EBioMedicine, 2017 Brown adipose tissue (BAT) represents a promising agent to ameliorate obesity and other metabolic disorders. However, the abundance of BAT decreases with age and BAT paucity is a common feature of obese subjects. As brown adipocytes and myoblasts share a
Chao Wang, Weiyi Liu, Feng Yue
exaly +3 more sources
MyoD Regulates Skeletal Muscle Oxidative Metabolism Cooperatively with Alternative NF-κB
Cell Reports, 2016 MyoD is a key regulator of skeletal myogenesis that directs contractile protein synthesis, but whether this transcription factor also regulates skeletal muscle metabolism has not been explored. In a genome-wide ChIP-seq analysis of skeletal muscle cells,
Jonathan Shintaku +2 more
exaly +3 more sources
Growth factors improve the proliferation of Jeju black pig muscle cells by regulating myogenic differentiation 1 and growth-related genes [PDF]
Animal Bioscience, 2021 Objective The growth rate of pigs is related to differentiation and proliferation of muscle cells, which are regulated by growth factors and expression of growth-related genes. Thus, the objective of this study was to establish optimal culture conditions
Jinryong Park +8 more
doaj +1 more source
PAX7 and MyoD Proteins Expression in Response to Eccentric and Concentric Resistance Exercise in Active Young Men [PDF]
Cell Journal, 2023 Objective: Satellite cells play an important role in muscle regeneration, which this process can be affected by differentgenes including PAX7 and MyoD. Exercise training known as an important strategy for mediating the satellite cell’sfunction. Therefore,
Somayeh Karimi Majd +2 more
doaj +1 more source
Sprouty2 mediated tuning of signalling is essential for somite myogenesis [PDF]
, 2015 Background: Negative regulators of signal transduction cascades play critical roles in controlling different aspects of normal embryonic development.
A Borycki +51 more
core +17 more sources
Italian Journal of Animal Science, 2021 The effects of Tenebrio molitor larvae meal (TM) dietary inclusion in rainbow trout diet were evaluated on muscular growth using gene expression and histomorphological features of liver, spleen, kidney, anterior and posterior gut through ...
Giulia Chemello +7 more
doaj +1 more source
Comparision the effect of high intensity interval training and continuous endurance training on expression of MYOD in Soleus muscle of diabetic rats [PDF]
فیزیولوژی ورزش و فعالیت بدنی, 2016 Purpose:Due to the development of diabetes and complications of the disease such as Muscular Atrophy, AndConsidering the role of exercise in the management of symptoms, The purpose of this study was to Comparison of highintensity interval training with ...
زهرا سلیمانی +1 more
doaj +1 more source
Calcium Homeostasis in Myogenic Differentiation Factor 1 (MyoD)-Transformed, Virally-Transduced, Skin-Derived Equine Myotubes [PDF]
, 2014 Dysfunctional skeletal muscle calcium homeostasis plays a central role in the pathophysiology of several human and animal skeletal muscle disorders, in particular, genetic disorders associated with ryanodine receptor 1 (RYR1) mutations, such as malignant
A Hovnanian +75 more
core +12 more sources