Results 11 to 20 of about 27,684 (229)

Jmjd2C increases MyoD transcriptional activity through inhibiting G9a-dependent MyoD degradation

open access: yesBiochimica Et Biophysica Acta - Gene Regulatory Mechanisms, 2015
Skeletal muscle cell differentiation requires a family of proteins called myogenic regulatory factors (MRFs) to which MyoD belongs. The activity of MyoD is under epigenetic regulation, however, the molecular mechanism by which histone KMTs and KDMs ...
Kye-Seong Kim   +2 more
exaly   +4 more sources

Conversion of MyoD to a Neurogenic Factor: Binding Site Specificity Determines Lineage

open access: yesCell Reports, 2015
MyoD and NeuroD2, master regulators of myogenesis and neurogenesis, bind to a “shared” E-box sequence (CAGCTG) and a “private” sequence (CAGGTG or CAGATG, respectively).
Abraham P. Fong   +6 more
doaj   +2 more sources

MUNC, an Enhancer RNA Upstream from the MYOD Gene, Induces a Subgroup of Myogenic Transcripts in trans Independently of MyoD

open access: yesMolecular and Cellular Biology, 2018
MyoD upstream noncoding RNA (MUNC) initiates in the distal regulatory region (DRR) enhancer of MYOD and is formally classified as an enhancer RNA (DRReRNA).
Anindya Dutta   +2 more
exaly   +2 more sources

Identification of MyoD-Responsive Transcripts Reveals a Novel Long Non-coding RNA (lncRNA-AK143003) that Negatively Regulates Myoblast Differentiation

open access: yesScientific Reports, 2017
Myogenic differentiation factor (MyoD) is a master transcription factor in muscle development and differentiation. Although several long non-coding RNAs (lncRNAs) linked to MyoD have been found to influence muscle development, the functions of many ...
Yiwen Guo   +6 more
doaj   +2 more sources

The muscle regulatory transcription factor MyoD participates with p53 to directly increase the expression of the pro-apoptotic Bcl2 family member PUMA

open access: yesApoptosis: an International Journal on Programmed Cell Death, 2017
The muscle regulatory transcription factor MyoD is a master regulator of skeletal myoblast differentiation. We have previously reported that MyoD is also necessary for the elevated expression of the pro-apoptotic Bcl2 family member PUMA, and the ensuing ...
, Terri Harford, Girish Shukla
exaly   +2 more sources

Growth factors improve the proliferation of Jeju black pig muscle cells by regulating myogenic differentiation 1 and growth-related genes [PDF]

open access: yesAnimal Bioscience, 2021
Objective The growth rate of pigs is related to differentiation and proliferation of muscle cells, which are regulated by growth factors and expression of growth-related genes. Thus, the objective of this study was to establish optimal culture conditions
Jinryong Park   +8 more
doaj   +1 more source

PAX7 and MyoD Proteins Expression in Response to Eccentric and Concentric Resistance Exercise in Active Young Men [PDF]

open access: yesCell Journal, 2023
Objective: Satellite cells play an important role in muscle regeneration, which this process can be affected by differentgenes including PAX7 and MyoD. Exercise training known as an important strategy for mediating the satellite cell’sfunction. Therefore,
Somayeh Karimi Majd   +2 more
doaj   +1 more source

Effects of Tenebrio molitor larvae meal inclusion in rainbow trout feed: myogenesis-related gene expression and histomorphological features

open access: yesItalian Journal of Animal Science, 2021
The effects of Tenebrio molitor larvae meal (TM) dietary inclusion in rainbow trout diet were evaluated on muscular growth using gene expression and histomorphological features of liver, spleen, kidney, anterior and posterior gut through ...
Giulia Chemello   +7 more
doaj   +1 more source

Dissecting dual roles of MyoD during lineage conversion to mature myocytes and myogenic stem cells

open access: yesGenes & Development, 2021
In this study, Yagi et al. dissected the transcriptional and epigenetic dynamics of mouse fibroblasts undergoing reprogramming to either myotubes or iMPCs using a MyoD-inducible transgenic model.
Masaki Yagi   +19 more
semanticscholar   +1 more source

Deltex2 represses MyoD expression and inhibits myogenic differentiation by acting as a negative regulator of Jmjd1c

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2017
Thomas A Rando, Dan Luo, Arjun Rustagi
exaly   +2 more sources

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