Results 81 to 90 of about 27,684 (229)
Muscle &Nerve, EarlyView.ABSTRACT Peripheral nerve injuries (PNIs) are a common cause of long‐term motor and sensory disability despite advances in microsurgical repair. Functional recovery following PNI depends not only on axonal regeneration, but also on preservation of distal nerve pathways, maintenance of neuromuscular junction integrity, prevention of irreversible muscle ...
Sarah M. Smith +5 more
wiley +1 more source
Skeletal Muscle, 2012 Background Mice lacking MyoD exhibit delayed skeletal muscle regeneration and markedly enhanced numbers of satellite cells. Myoblasts isolated from MyoD-/- myoblasts proliferate more rapidly than wild type myoblasts, display a dramatic delay in ...
Parker Maura H +6 more
doaj +1 more source
HDAC11 Inhibits Myoblast Differentiation through Repression of MyoD-Dependent Transcription
Molecules and Cells, 2017 Abnormal differentiation of muscle is closely associated with aging (sarcopenia) and diseases such as cancer and type II diabetes. Thus, understanding the mechanisms that regulate muscle differentiation will be useful in the treatment and prevention of ...
S. Byun +10 more
semanticscholar +1 more source
Small, EarlyView.A magnetic stimulation platform for the remote stimulation of cells is presented, consisting of a magnetic stimulator and magnetic microspheres. Skeletal muscle cells are labeled with magnetic microspheres, which act as local magnetic actuators on the cells upon application of the magnetic field.
Tayná C. Rodrigues +14 more
wiley +1 more source
Developmental Cell, 2016 SUMMARY Most transcription factor families contain highly related paralogs generated by gene duplication and functional divergence is generally accomplished by activation of distinct sets of genes by each member.
M. Conerly +4 more
semanticscholar +1 more source
MXene Bioinks for 3D Bioprinting: Design and Translation
Small, EarlyView.This study establishes a comprehensive framework for MXene‐based bioinks in 3D bioprinting, highlighting the interplay between rheological engineering and electroactive hydrogels. By optimizing electrical percolation and mediated signaling, these formulations drive tissue‐specific biological outcomes and accelerated regeneration.
Begüm Sarac +2 more
wiley +1 more source
NFATc1 Controls Skeletal Muscle Fiber Type and Is a Negative Regulator of MyoD Activity
Cell Reports, 2014 Skeletal muscle comprises a heterogeneous population of fibers with important physiological differences. Fast fibers are glycolytic and fatigue rapidly. Slow fibers utilize oxidative metabolism and are fatigue resistant.
Melissa L. Ehlers +2 more
doaj +1 more source
MyoD, a Lesson in Widespread DNA Binding [PDF]
Developmental Cell, 2010 There is growing recognition that animal transcription factors bind in vivo to far more genomic regions than generally assumed earlier. In this issue of Developmental Cell, Cao et al. show that the muscle specification factor MyoD binds to regions near most genes and modifies chromatin states at these sites.
openaire +2 more sources
Cell Proliferation, EarlyView.Polyamine metabolism is innervation responsive and involved in denervation‐induced muscle atrophy. Inhibition of polyamine metabolism attenuates muscle atrophy by restraining proteolysis and preserving MuSCs homeostasis. Denervation‐induced activation of FAP‐derived FGF7 drives premature MuSCs activation, while DFMO suppresses this paracrine cue to ...
Mingming Zhang +9 more
wiley +1 more source
Finding MyoD and lessons learned along the way
Seminars in Cell and Developmental Biology, 2017 In 1987, Robert Davis, Hal Weintraub and I reported the identification of MyoD, a transcription factor that could reprogram fibroblasts into skeletal muscle cells.
A. Lassar
semanticscholar +1 more source