Evaluation of Myofibroblasts by Expression of Alpha Smooth Muscle Actin: A Marker in Fibrosis, Dysplasia and Carcinoma [PDF]
Journal of Clinical and Diagnostic Research, 2014 Objective: Evaluation of Myofibroblasts by studying expression of Alpha smooth muscle actin: A marker of Fibrosis, Dysplasia and Carcinoma. Background: Myofibroblasts are cells that have contractile properties and are involved in inflammation, wound ...
Bharath Rao K +3 more
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Targeted apoptosis of myofibroblasts by elesclomol inhibits hypertrophic scar formation
EBioMedicine, 2020 Background: Hypertrophic scar (HS) is characterized by the increased proliferation and decreased apoptosis of myofibroblasts. Myofibroblasts, the main effector cells for dermal fibrosis, develop from normal fibroblasts.
Yi Feng +8 more
doaj +1 more source
A two-compartment mechanochemical model of the roles of\ud transforming growth factor β and tissue tension in dermal wound healing [PDF]
, 2011 The repair of dermal tissue is a complex process of interconnected phenomena, where cellular, chemical and mechanical aspects all play a role, both in an autocrine and in a paracrine fashion.
Hall, C. L. +4 more
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Human liver myofibroblasts during development and diseases with a focus on portal (myo)fibroblasts.
Frontiers in Physiology, 2015 Myofibroblasts are stromal cells mainly involved in tissue repair. These cells present contractile properties and play a major role in extracellular matrix deposition and remodeling. In liver, myofibroblasts are found in two critical situations.
Sébastien eLepreux +1 more
doaj +1 more source
Myofibroblasts Are Not Characteristic Features of Keloid Lesions
Plastic and Reconstructive Surgery, Global Open, 2022 Background:. Keloids are disfiguring, scar-like lesions that are challenging to treat, with low response rates to current interventions and frequent recurrence.
Jennifer M. Hahn, BS +4 more
doaj +1 more source
Involvement of pro-inflammatory cytokines and growth factors in the pathogenesis of Dupuytren's contracture: a novel target for a possible future therapeutic strategy? [PDF]
, 2015 Dupuytren's contracture (DC) is a benign fibro-proliferative disease of the hand causing fibrotic nodules and fascial cords which determine debilitating contracture and deformities of fingers and hands.
Alberto Signore +11 more
core +1 more source
The role of myofibroblasts in orthodontic tooth movement
口腔疾病防治, 2019 Myofibroblasts are fibroblasts with contractile function. As a contractile cell, myofibroblasts can regulate the function of normal organs in normal tissues.
PAN Xumeng, LIU Yi
doaj +1 more source
Stromal Myofibroblasts Are Associated with Poor Prognosis in Solid Cancers: A Meta-Analysis of Published Studies. [PDF]
PLoS ONE, 2016 Published studies have evaluated the impact of stromal myofibroblasts on prognosis in solid cancers. However, the results of these studies remain controversial.
Liu Liu +5 more
doaj +1 more source
Characterisation of feline renal cortical fibroblast cultures and their transcriptional response to transforming growth factor beta 1 [PDF]
, 2018 Chronic kidney disease (CKD) is common in geriatric cats, and the most prevalent pathology is chronic tubulointerstitial inflammation and fibrosis. The cell type predominantly responsible for the production of extra-cellular matrix in renal fibrosis is ...
A Clayton +58 more
core +2 more sources
Multicentric myofibroblastic sarcoma [PDF]
BMJ Case Reports, 2014 We report a case of synchronous, multicentric low-grade myofibroblastic sarcoma presenting in a 62-year-old man. He initially presented with inflammatory symmetric polyarthritis and adhesive capsulitis of his shoulder and hips bilaterally and did not respond to a trial of disease modifying antirheumatic drugs.
Mihir Dilip, Wechalekar +4 more
openaire +2 more sources