Results 1 to 10 of about 53,888 (279)

Posttranslational control of membrane-skeleton (ankyrin and alpha beta- spectrin) assembly in early myogenesis [PDF]

, 1985
Adult chicken skeletal muscle cells express polypeptides that are antigenically related to alpha-spectrin (Mr 240,000) and beta-spectrin (Mr 220,000-225,000), the major components of the erythrocyte membrane- skeleton, and to ankyrin (Mr 237,000; also ...
Lazarides, Elias, Nelson, W. James
core   +3 more sources

CircHOMER1 in mediating porcine skeletal muscle development [PDF]

BMC Genomics
Background Skeletal muscle serves as the principal source of high-quality protein in human nutrition. Recent studies indicate that circRNAs play key roles in myogenesis by acting as competing endogenous RNAs (ceRNAs).
Meng Li, Yuxuan Gong, Shuangji Ma, Jiayi Chen, Wanfeng Zhang, Yang Yang, Guoqing Cao, Xiaohong Guo, Bugao Li   +8 more
doaj   +2 more sources

Disruption of the mouse MRF4 gene identifies multiple waves of myogenesis in the myotome [PDF]

, 1995
MRF4 (herculin/Myf-6) is one of the four member MyoD family of transcription factors identified by their ability to enforce skeletal muscle differentiation upon a wide variety of nonmuscle cell types.
Miner, Jeffrey H., Patapoutian, Ardem, Stark, Kevin, Wang, Shuling, Wold, Barbara, Yoon, Jeong Kyo   +5 more
core   +3 more sources

Overexpression of syndecan-4 inhibits myogenesis by regulating the expression of myogenic regulatory factors [PDF]

Journal of Animal Science and Technology
Syndecan-4, a type of heparin sulfate proteoglycan, plays an important role in muscle development, regeneration, and maintenance. Although, the important effects of syndecan-4 on the regulation of myogenesis in mice, turkeys, and bovines have been ...
Sarang Choi, Jeong-Woong Park, Sang In Lee, Sangsu Shin   +3 more
doaj   +2 more sources

Stage-specific requirement for METTL3-dependent m6A epitranscriptomic regulation during myogenesis [PDF]

Communications Biology
The regulatory role of N6-methyladenosine (m6A) modification in skeletal muscle myogenesis and muscle homeostasis remains poorly characterized, particularly regarding the functional significance of methyltransferase-like 3 (METTL3), the catalytic subunit
Ye-Ya Tan, Yang-Wen Ou, Qin Zuo, Yi Luo, Wei-Cai Chen, Wan-Xin Chen, Xin-Wang Zhi, Pei-Wen Lin, Jia-Xing Lu, Peng Liu, Si-Min Liang, Qing-Hai Lian, Lian-Dong Zuo, Hong-Wen Xu, Shu-Juan Xie   +14 more
doaj   +2 more sources

DNM1L-mediated fission governs mitophagy & mitochondrial biogenesis during myogenic differentiation [PDF]

Cell Communication and Signaling
Background Remodeling of the mitochondrial network is implicated in myogenesis. Remodeling processes including mitochondrial fission, mitophagy, and biogenesis are important as they finetune the mitochondrial network to meet the increased energetic ...
Fasih A. Rahman, Jasmine M. Friedrich Yap, Tyler M. Joseph, Amanda M. Adam, Sarah M. Chapman, Joe Quadrilatero   +5 more
doaj   +2 more sources

Pitx2 Differentially Regulates the Distinct Phases of Myogenic Program and Delineates Satellite Cell Lineages During Muscle Development

Frontiers in Cell and Developmental Biology, 2022
The knowledge of the molecular mechanisms that regulate embryonic myogenesis from early myogenic progenitors to myoblasts, as well as the emergence of adult satellite stem cells (SCs) during development, are key concepts to understanding the genesis and ...
Felícitas Ramírez de Acuña, Felícitas Ramírez de Acuña, Francisco Hernandez-Torres, Francisco Hernandez-Torres, Francisco Hernandez-Torres, Lara Rodriguez-Outeiriño, Lara Rodriguez-Outeiriño, Jorge N. Dominguez, Jorge N. Dominguez, Lidia Matias-Valiente, Lidia Matias-Valiente, Cristina Sanchez-Fernandez, Cristina Sanchez-Fernandez, Diego Franco, Diego Franco, Amelia E. Aranega, Amelia E. Aranega   +16 more
doaj   +1 more source

miR-106b is a novel target to promote muscle regeneration and restore satellite stem cell function in injured Duchenne dystrophic muscle

Molecular Therapy: Nucleic Acids, 2022
Satellite cells (SCs), muscle stem cells, display functional heterogeneity, and dramatic changes linked to their regenerative capabilities are associated with muscle-wasting diseases.
Lara Rodriguez-Outeiriño, Francisco Hernandez-Torres, Felicitas Ramirez de Acuña, Alberto Rastrojo, Carlota Creus, Alejandra Carvajal, Luis Salmeron, Marisol Montolio, Patricia Soblechero-Martin, Virginia Arechavala-Gomeza, Diego Franco, Amelia Eva Aranega   +11 more
doaj   +1 more source

Mitochondrial Oxidative Stress and Mitophagy Activation Contribute to TNF-Dependent Impairment of Myogenesis

Antioxidants, 2023
Many muscular pathologies are associated with oxidative stress and elevated levels of the tumor necrosis factor (TNF) that cause muscle protein catabolism and impair myogenesis.
Daniil A. Chernyavskij, Olga Yu. Pletjushkina, Anastasia V. Kashtanova, Ivan I. Galkin, Anna Karpukhina, Boris V. Chernyak, Yegor S. Vassetzky, Ekaterina N. Popova   +7 more
doaj   +1 more source

TNF Signaling Acts Downstream of MiR-322/-503 in Regulating DM1 Myogenesis

Frontiers in Endocrinology, 2022
Myotonic dystrophy type 1 (DM1) is caused by the expanded CUG repeats and usually displays defective myogenesis. Although we previously reported that ectopic miR-322/-503 expression improved myogenesis in DM1 by targeting the toxic RNA, the underlying ...
Meng Li, Meng Li, Meng Li, Feng Xu, Zhongxian Liu, Zhongxian Liu, Zhongxian Liu, Chunguang Wang, Chunguang Wang, Chunguang Wang, Yun Zhao, Yun Zhao, Yun Zhao, Guoping Zhu, Guoping Zhu, Guoping Zhu, Xiaopeng Shen, Xiaopeng Shen, Xiaopeng Shen   +18 more
doaj   +1 more source