Results 131 to 140 of about 55,400 (275)
Polyomavirus genome and polyomavirus enhancer-driven gene expression during myogenesis [PDF]
Rossella Maione +4 more
openalex +1 more source
DNA-PKcs regulates myogenesis in an AKT-dependent manner independent of induced DNA damage [PDF]
Haser Hasan Sutcu, Miria Ricchetti
openalex +1 more source
ABSTRACT Background Gestational diabetes mellitus (GDM), a common pregnancy complication characterized by maternal hyperglycemia, negatively impacts offspring health. Skeletal muscle, a critical tissue for glucose and lipid metabolism, is especially vulnerable to prenatal environmental insults.
Rui Liu +7 more
wiley +1 more source
Hes6 acts in a positive feedback loop with the neurogenins to promote neuronal differentiation [PDF]
During the development of the vertebrate nervous system, neurogenesis is promoted by proneural bHLH proteins such as the neurogenins, which act as potent transcriptional activators of neuronal differentiation genes.
Anderson, David J. +3 more
core
Current Trends in Duchenne Muscular Dystrophy Research and Therapy: 3D Cardiac Modelling
ABSTRACT Duchenne muscular dystrophy (DMD), caused by dystrophin deficiency, presents a multifaceted challenge that affects both skeletal muscle function and cardiomyocyte homeostasis, causing progressive degeneration and life‐threatening cardiac complications by adolescence.
Marta Przymuszała +3 more
wiley +1 more source
DNM1L-mediated fission governs mitophagy & mitochondrial biogenesis during myogenic differentiation
Background Remodeling of the mitochondrial network is implicated in myogenesis. Remodeling processes including mitochondrial fission, mitophagy, and biogenesis are important as they finetune the mitochondrial network to meet the increased energetic ...
Fasih A. Rahman +5 more
doaj +1 more source
ABSTRACT Background Current treatments for knee osteoarthritis (OA) offer limited functional and structural improvements. Compared to age‐ and gender‐matched controls, patients with knee OA show a higher prevalence of muscle weakness, which negatively affects their ability to exercise—a key factor in enhancing physical mobility and delaying disease ...
Kenney Ki Lee Lau +6 more
wiley +1 more source
Thrombin Causes a Marked Delay in Skeletal Myogenesis That Correlates with the Delayed Expression of Myogenin and p21 [PDF]
Denis C. Guttridge +3 more
openalex +1 more source
Annexin A2 Causes Motor Incoordination via Muscle–Cerebellum Axis in Sarcopenia
ABSTRACT Background Sarcopenia is a prevalent age‐related disorder characterized by progressive muscle atrophy. Impaired balance is one of its most critical clinical consequences, often leading to falling and even bone fractures. As the cerebellum plays a central role in regulating motor coordination, elucidating the molecular mechanisms underlying ...
Xin Jiao +16 more
wiley +1 more source
ABSTRACT Background Sarcopenic obesity, where excess body fat coexists with reduced muscle mass and function, is becoming increasingly common in ageing populations and contributes to poor physical and metabolic health. Although adipose tissue–secreted factors are implicated in muscle decline, the specific mechanisms remain unclear.
Joshua M. J. Price +8 more
wiley +1 more source

