Results 141 to 150 of about 54,460 (292)

Hemoglobin Nanofibrils as Electrospun Cell Scaffolds to Enhance Primary Satellite Cell Proliferation and Differentiation for Muscle Regeneration

open access: yesJournal of Biomedical Materials Research Part A, Volume 114, Issue 5, May 2026.
The fabricated cell scaffolds in this work facilitated enhanced satellite cell infiltration, preserved their differentiation potential, and promoted the initiation of myogenesis. ABSTRACT Stem cells are usually sensitive to extracellular matrix (ECM), and an effective synthetic ECM to mimic there in vivo growth surroundings is always desired.
Qun Chen   +5 more
wiley   +1 more source

TIMP1 Links Extracellular Matrix Remodeling With Immune Contexture and Outcome in Head and Neck Squamous Cell Carcinoma

open access: yesOral Science International, Volume 23, Issue 2, May 2026.
ABSTRACT Objective Tissue inhibitor of metalloproteinase‐1 (TIMP1) is a secreted glycoprotein that controls matrix metalloproteinase activity and exerts pleiotropic signaling functions. We investigated the clinical relevance of TIMP1 in head and neck squamous cell carcinoma (HNSCC; TCGA‐HNSC), focusing on survival, immunologic contexture, pathway ...
Aiko Kurosaka   +2 more
wiley   +1 more source

Stage-specific requirement for METTL3-dependent m6A epitranscriptomic regulation during myogenesis

open access: yesCommunications Biology
The regulatory role of N6-methyladenosine (m6A) modification in skeletal muscle myogenesis and muscle homeostasis remains poorly characterized, particularly regarding the functional significance of methyltransferase-like 3 (METTL3), the catalytic subunit
Ye-Ya Tan   +14 more
doaj   +1 more source

The role of primary cilia in myoblast proliferation and cell cycle regulation during myogenesis

open access: yesCell Structure and Function
The process of mammalian myogenesis is fundamental to understanding muscle development and holds broad relevance across multiple fields, from developmental biology to regenerative medicine.
Zhichao Wu, Nuo Chen, Daisuke Takao
doaj   +1 more source

Mitochondrial Transfer in the Tumor Microenvironment

open access: yesCancer Science, Volume 117, Issue 5, Page 1189-1198, May 2026.
Mitochondria are actively exchanged among tumor, immune, stromal, and neuronal cells within the tumor microenvironment. Such transfer rewires tumor metabolism, promotes immune evasion, and drives therapy resistance. Targeting mitochondrial transfer or harnessing mitochondrial transplantation represents a promising strategy to restore antitumor immunity
Ryo Omae   +2 more
wiley   +1 more source

Mechanobiology in Stem Cell‐Based Bioprinting

open access: yesCell Proliferation, Volume 59, Issue 5, May 2026.
Mechanobiology in stem cell‐based bioprinting is an emerging field that bridges the mechanical conditions of the bioprinting process with the regulation of stem cell behaviour for engineering living tissues. Stresses encountered during bioprinting, together with the mechanical properties of bioinks, play a critical role in regulating stem cell ...
Supeng Ding, Tiankun Liu, Rui Yao
wiley   +1 more source

Lipid emulsion modulates myogenic and collagen‐related gene expression in skeletal muscle of preterm fetal sheep

open access: yesExperimental Physiology, Volume 111, Issue 5, Page 2627-2636, 1 May 2026.
Abstract Although intravenous lipid emulsions are routinely administered to preterm infants, their specific effects on skeletal muscle development remain unclear. In this study, a soybean oil‐based lipid emulsion (Intralipid 20®) was administered via intravenous infusion to fetal sheep (gestational day 88–90) at a dose rising from 1 g/kg/day (day 0) to
Xinrui Li   +5 more
wiley   +1 more source

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