Results 131 to 140 of about 32,565 (245)
This study investigated the bidirectional relationship and shared mechanisms between sarcopenia and osteoporosis using data from the UK Biobank. Our findings indicated that the two conditions may act as reciprocal risk factors, with multiple potential biomarkers mediating the muscle‐bone relationship and suggested possible shared signals between the ...
Siqi Xu +10 more
wiley +1 more source
A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou +4 more
wiley +1 more source
Genomic Analysis of Inbreeding Depression on Productive Traits in Rubia Galega Beef Cattle Breed
ABSTRACT In autochthonous livestock breeds with small populations, such as the Rubia Galega from Galicia (Spain), mating between relatives is common and can lead to inbreeding depression. Genomic inbreeding coefficients were estimated for 4984 animals using ~63,000 SNPs to assess inbreeding depression in four key traits: age at first calving (AFC) with
N. Mejuto‐Vázquez +6 more
wiley +1 more source
p38, ERK1/2, and AKT phosphorylation during C2C12 skeletal myogenesis. (A) Representative Western blots evaluating the phosphorylation of p38, ERK1/2, and AKT during a 6-day time curse of skeletal myogenesis using the C2C12 myoblast cell line.
Osvaldo Contreras (780538) +2 more
core +1 more source
Multi‐Omics Landscape of Paraspinal Muscles in Spinal Muscular Atrophy With Scoliosis
ABSTRACT Most spinal muscular atrophy (SMA) patients develop severe scoliosis by late adolescence. Given that the paraspinal muscles—particularly the multifidus—are indispensable for maintaining spinal stability, their site‐specific multi‐omics characteristics in SMA remain insufficiently defined. Herein, integrated multi‐omics sequencing was performed
Zhen Wang +4 more
wiley +1 more source
Unorthodox myogenesis, possi ble developmental significance and implications for tissue histogenesis and regeneration [PDF]
During the last few years several reports have described the occurrence of skeletal myogenesis in cells derived from embryonic, fetal and perinatal tissues that usually do not contribute to skeletal muscle in the adult vertebrate body. After a brief
Cossu, G.
core
Bovine myoblast stimulation for enhancing myogenesis
Introduction: Several challenges account for the slow progress of cultured meat production. Primary bovine muscle stem cells have limited cell growth and lose their myogenic differentiation capacity to myotubes after expansion and the resulting myotubes ...
Deelkens, Chloë, Thorrez, Lieven
core
UNDERSTANDING THE ROLE OF TBX3 IN MYOGENESIS
Myogenesis, the formation of muscular tissues, requires the precise expression of myogenic regulatory factors (MRFs), whose expression regulates transcription of muscle specific genes. TBX3 is a member of the T-box family of transcription factors that is
ALTHOBAITI, AIYSHA NASSER
core
FUNCTION OF AMP-ACTIVATED PROTEIN KINASE IN MYOGENESIS
Thesis (Ph.D.), Washington State UniversityProper skeletal muscle development is crucial for human health and meat production. AMPK is the master metabolism regulator, but the role of AMPK in myogenesis remains poorly defined. Previous studies using AMPK
Fu, Xing
core

