Results 131 to 140 of about 54,460 (292)

Post‐exercise ketone supplementation improves endurance performance and mitochondrial adaptations during an 8‐week endurance training intervention

The Journal of Physiology, EarlyView.
Abstract figure legend Twenty‐eight trained males completed 8 weeks of supervised indoor cycling training, receiving post‐exercise and pre‐sleep ketone monoester (KE, n = 14) or isocaloric placebo (CON, n = 14). Both groups improved 30 min time‐trial performance with training, but KE achieved a 4% higher power output than CON at the end of the training
Ruben Robberechts, Youri Bekhuis, Myrthe Stalmans, Wout Lauriks, Martijn Kusters, Karim Taha, Thomas Rosseel, Guido Claessen, Chiel Poffé   +8 more
wiley   +1 more source

Biomaterial Physical Cues as Gene Regulators for Cellular Agriculture

Advanced Genetics, Volume 7, Issue 2, June 2026.
This review elucidates how biomaterial physical cues—ranging from matrix stiffness to remote electromagnetic fields—serve as extrinsic regulators of gene expression in cellular agriculture. By identifying central mechanotransduction pathways that bridge physical inputs to genetic remodeling, the authors propose the “Material Genome” concept: a ...
Jianuo Liu, Ye Liu
wiley   +1 more source

Systemic Drivers and Molecular Mechanisms of Sarcopenia in Aetiology‐Specific End‐Stage Liver Disease

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Patients with end‐stage liver disease (ESLD) often present with sarcopenia, defined as loss of skeletal muscle mass and quality, which is associated with reduced quality of life and increased mortality. However, the molecular mechanisms driving sarcopenia in ESLD are not fully understood and there are currently no therapeutic ...
Thomas Nicholson, Sophie L. Allen, Jonathan I. Quinlan, Amritpal Dhaliwal, Michael Macleod, Joshua Price, Jon Hazeldine, Michael S. Sagmeister, Caitlin Ditchfield, Kirsty C. McGee, Felicity R. Williams, Ahmed M. Elsharkawy, Matthew J. Armstrong, Carolyn A. Greig, Janet M. Lord, Leigh Breen, Simon W. Jones   +16 more
wiley   +1 more source

Deubiquitinase YOD1 Inhibition Suppresses DEX‐ and Denervation‐Induced Muscle Atrophy Through MAFbx Destabilization

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Backgrounds Muscle atrophy, characterized by progressive loss of muscle mass and function, is driven by muscle‐specific E3 ligases MAFbx and MuRF1. While transcriptional regulation of E3 ligases is documented, the mechanism of their regulation by the ubiquitin–proteasome system remains unclear. This study aims to identify a deubiquitinase (DUB)
Jongbeom Chae, Seon Min Woo, Seung Un Seo, Simmyung Yook, Hyo Je Cho, Jung Yeol Lee, Kyoung jin Min, Junhyeon Park, Dongryeol Ryu, Taeg Kyu Kwon   +9 more
wiley   +1 more source

Elevated Circulating Ceramides 18:0 and 24:1 as a Risk Factor for Sarcopenia: In Vitro, Animal, and Clinical Evidence

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Ceramides have garnered considerable attention as pro‐aging bioactive lipids implicated in both metabolic dysfunction and musculoskeletal decline. Among these, C18:0 and C24:1 ceramides may play a role in the pathophysiology of sarcopenia, a key manifestation of age‐related deterioration.
So Jeong Park, Ji Yeon Baek, Shibo Wei, Jin Young Lee, Yuna Lee, Sang‐Hoon Lee, Il‐Young Jang, Hyuk Sakong, Hyun Ju Yoo, Hee‐Won Jung, Eunju Lee, Su Jung Kim, Yunju Jo, Kyunggon Kim, Dongryeol Ryu, Beom‐Jun Kim   +15 more
wiley   +1 more source

VGLL3 Regulates DAPK2‐Mediated Autophagy During Osteoblast Differentiation

BioFactors, Volume 52, Issue 3, May/June 2026.
VGLL3 regulates autophagic activity during osteoblast differentiation and is associated with DAPK2‐mediated autophagy. Overexpression of Dapk2 partially restores autophagy and osteogenic differentiation in Vgll3‐deficient osteoblasts. ABSTRACT Vestigial‐like family member 3 (VGLL3), a transcriptional cofactor of the TEA domain family, has been ...
Yuhan He, Ziyi Wang, Yao Weng, Heriati Sitosari, Yilin Zheng, Yaxin Qu, Mika Ikegame, Hirohiko Okamura   +7 more
wiley   +1 more source

DNM1L-mediated fission governs mitophagy & mitochondrial biogenesis during myogenic differentiation

Cell Communication and Signaling
Background Remodeling of the mitochondrial network is implicated in myogenesis. Remodeling processes including mitochondrial fission, mitophagy, and biogenesis are important as they finetune the mitochondrial network to meet the increased energetic ...
Fasih A. Rahman, Jasmine M. Friedrich Yap, Tyler M. Joseph, Amanda M. Adam, Sarah M. Chapman, Joe Quadrilatero   +5 more
doaj   +1 more source

KDM4A regulates myogenesis by demethylating H3K9me3 of myogenic regulatory factors [PDF]

, 2021
Qi Zhu, Liang Feng, Shufang Cai, Xiaorong Luo, Tianqi Duo, Ziyun Liang, Zuyong He, Yaosheng Chen, Delin Mo   +8 more
openalex   +1 more source

Next‐Generation Sustainable Food Production Through Integrative Biotechnology, AI, and Climate‐Resilient Innovations

Food and Energy Security, Volume 15, Issue 3, May/June 2026.
ABSTRACT By 2050, the global population is projected to reach ~10 billion, leading to 50% increase in food demand. This growth will place immense pressure on agricultural systems that are already struggling with the impacts of climate change and resource depletion.
Chaquayla Katam, Hajra Maqsood, Brooke Bucci, Sixue Chen   +3 more
wiley   +1 more source

Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration [PDF]

, 2021
Karolina Archacka, Maria A. Ciemerych, Anita Florkowska, Karolina Romańczuk   +3 more
openalex   +1 more source