Results 21 to 30 of about 53,888 (279)
Sprouty2 mediated tuning of signalling is essential for somite myogenesis [PDF]
, 2015 Background: Negative regulators of signal transduction cascades play critical roles in controlling different aspects of normal embryonic development.
A Borycki +51 more
core +2 more sources
Coordinated actions of microRNAs with other epigenetic factors regulate skeletal muscle development and adaptation [PDF]
, 2017 Epigenetics plays a pivotal role in regulating gene expression in development, in response to cellular stress or in disease states, in virtually all cell types.
Adamo, Sergio +3 more
core +1 more source
Adjuvant pharmacological strategies for the musculoskeletal system during long‐term space missions
British Journal of Clinical Pharmacology, EarlyView., 2023 Abstract Despite 2 h of daily exercise training, muscle wasting and bone loss are still present after 6‐month missions to the international space station. Some crew members lose bone much faster than others. In preparation for missions to the Moon and Mars, space agencies are therefore reviewing their countermeasure portfolios.
Friederike Thomasius +2 more
wiley +1 more source
PITX2 Enhances the Regenerative Potential of Dystrophic Skeletal Muscle Stem Cells
Stem Cell Reports, 2018 Summary: Duchenne muscular dystrophy (DMD), one of the most lethal genetic disorders, involves progressive muscle degeneration resulting from the absence of DYSTROPHIN.
Daniel Vallejo +7 more
doaj +1 more source
Itaconate and Its Derivatives Repress Early Myogenesis In Vitro and In Vivo
Frontiers in Immunology, 2022 A Krebs cycle intermediate metabolite, itaconate, has gained attention as a potential antimicrobial and autoimmune disease treatment due to its anti-inflammatory effects.
Tae Seok Oh +5 more
doaj +1 more source
Epigenetic regulation of myogenesis [PDF]
Epigenetics, 2009 Adult skeletal muscle provides a unique paradigm for studying stem to differentiated cell transitions. In response to environmental stress, quiescent muscle stem cells (satellite cells) are activated and proliferative, at which stage they can either differentiate and fuse to form new muscle fibers or alternatively self-renew and maintain the muscle ...
Eusebio Perdiguero +3 more
openaire +2 more sources
Stem Cell Reports, 2017 Summary: In skeletal muscle, new functions for vessels have recently emerged beyond oxygen and nutrient supply, through the interactions that vascular cells establish with muscle stem cells. Here, we demonstrate in human and mouse that endothelial cells (
Claire Latroche +14 more
doaj +1 more source
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2020 Skeletal muscles have an immense ability to regenerate from the muscle stem cells called satellite cells. The process of skeletal muscle regeneration is called myogenesis, which starts with activation of quiescent satellite cells immediately after muscle injury followed by proliferation and fusion of myoblasts into myotubes.
Debojyoti Das +4 more
openaire +3 more sources
Comparative myogenesis in teleosts and mammals [PDF]
Cellular and Molecular Life Sciences, 2014 Skeletal myogenesis has been and is currently under extensive study in both mammals and teleosts, with the latter providing a good model for skeletal myogenesis because of their flexible and conserved genome. Parallel investigations of muscle studies using both these models have strongly accelerated the advances in the field. However, when transferring
G. Rossi, G. Messina
openaire +3 more sources
Prdm1 (Blimp-1) and the Expression of Fast and Slow Myosin Heavy Chain Isoforms during Avian Myogenesis In Vitro [PDF]
, 2010 BACKGROUND. Multiple types of fast and slow skeletal muscle fibers form during early embryogenesis in vertebrates. In zebrafish, formation of the earliest slow myofibers in fin muscles requires expression of the zinc-finger transcriptional repressor ...
Ardelt, Magdalena +3 more
core +4 more sources