Results 21 to 30 of about 55,400 (275)

Inhibition of Postn Rescues Myogenesis Defects in Myotonic Dystrophy Type 1 Myoblast Model

Frontiers in Cell and Developmental Biology, 2021
Myotonic dystrophy type 1 (DM1) is an inherited neuromuscular disease caused by expanded CTG repeats in the 3′ untranslated region (3′UTR) of the DMPK gene.
Xiaopeng Shen, Xiaopeng Shen, Xiaopeng Shen, Zhongxian Liu, Zhongxian Liu, Zhongxian Liu, Chunguang Wang, Chunguang Wang, Chunguang Wang, Feng Xu, Feng Xu, Feng Xu, Jingyi Zhang, Jingyi Zhang, Jingyi Zhang, Meng Li, Meng Li, Meng Li, Yang Lei, Ao Wang, Ao Wang, Ao Wang, Chao Bi, Chao Bi, Chao Bi, Guoping Zhu, Guoping Zhu, Guoping Zhu   +27 more
doaj   +1 more source

Time-resolved phosphoproteome and proteome analysis reveals kinase signaling on master transcription factors during myogenesis

iScience, 2022
Summary: Myogenesis is governed by signaling networks that are tightly regulated in a time-dependent manner. Although different protein kinases have been identified, knowledge of the global signaling networks and their downstream substrates during ...
Di Xiao, Marissa Caldow, Hani Jieun Kim, Ronnie Blazev, Rene Koopman, Deborah Manandi, Benjamin L. Parker, Pengyi Yang   +7 more
doaj   +1 more source

Disease-associated metabolic alterations that impact satellite cells and muscle regeneration: perspectives and therapeutic outlook

Nutrition & Metabolism, 2021
Many chronic disease patients experience a concurrent loss of lean muscle mass. Skeletal muscle is a dynamic tissue maintained by continuous protein turnover and progenitor cell activity. Muscle stem cells, or satellite cells, differentiate (by a process
Josiane Joseph, Jason D. Doles
doaj   +1 more source

Comparative analyses by sequencing of transcriptomes during skeletal muscle development between pig breeds differing in muscle growth rate and fatness. [PDF]

PLoS ONE, 2011
Understanding the dynamics of muscle transcriptome during development and between breeds differing in muscle growth is necessary to uncover the complex mechanism underlying muscle development.
Xiao Zhao, Delin Mo, Anning Li, Wen Gong, Shuqi Xiao, Yue Zhang, Limei Qin, Yuna Niu, Yunxue Guo, Xiaohong Liu, Peiqing Cong, Zuyong He, Chong Wang, Jiaqi Li, Yaosheng Chen   +14 more
doaj   +1 more source

Pitx2 in Embryonic and Adult Myogenesis

Frontiers in Cell and Developmental Biology, 2017
Skeletal muscle is a heterogeneous tissue that represents between 30 and 38% of the human body mass and has important functions in the organism, such as maintaining posture, locomotor impulse, or pulmonary ventilation.
Amelia E. Aranega, Amelia E. Aranega, Francisco Hernandez-Torres, Francisco Hernandez-Torres, Lara Rodríguez-Outeiriño, Lara Rodríguez-Outeiriño, Diego Franco, Diego Franco   +7 more
doaj   +1 more source

Sprouty2 mediated tuning of signalling is essential for somite myogenesis [PDF]

, 2015
Background: Negative regulators of signal transduction cascades play critical roles in controlling different aspects of normal embryonic development.
A Borycki, A Faedo, A Sasaki, AA Mailleux, AC Rios, Andrea Münsterberg, B Christ, B Hausott, C de Alvaro, C Marcelle, C Zhang, CC Lee, D Chambers, D Sayed, D Sweetman, D Sweetman, G Christofori, G Minowada, GF Mok, Grant Wheeler, H Hanafusa, HJ Kim, HM Poppleton, I Laziz, JD Tefft, JM Mason, JM Mason, K Matsumura, K Shim, Katarzyna Goljanek Whysall, L Cheng, L Chi, L Chi, LE Alvares, M Abu-Elmagd, M Buckingham, M Ishida, M Schmidt, M Schmidt, MA Basson, MA Cabrita, MC Eblaghie, MJ Frank, Muhammad Abu-Elmagd, N Hacohen, OD Klein, P Li, PA Branney, S Eloy-Trinquet, TG Smith, V Hamburger, Y Yigzaw   +51 more
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Posttranslational control of membrane-skeleton (ankyrin and alpha beta- spectrin) assembly in early myogenesis [PDF]

, 1985
Adult chicken skeletal muscle cells express polypeptides that are antigenically related to alpha-spectrin (Mr 240,000) and beta-spectrin (Mr 220,000-225,000), the major components of the erythrocyte membrane- skeleton, and to ankyrin (Mr 237,000; also ...
Lazarides, Elias, Nelson, W. James
core   +1 more source

PITX2 Enhances the Regenerative Potential of Dystrophic Skeletal Muscle Stem Cells

Stem Cell Reports, 2018
Summary: Duchenne muscular dystrophy (DMD), one of the most lethal genetic disorders, involves progressive muscle degeneration resulting from the absence of DYSTROPHIN.
Daniel Vallejo, Francisco Hernández-Torres, Estefanía Lozano-Velasco, Lara Rodriguez-Outeiriño, Alejandra Carvajal, Carlota Creus, Diego Franco, Amelia Eva Aránega   +7 more
doaj   +1 more source

Prdm1 (Blimp-1) and the Expression of Fast and Slow Myosin Heavy Chain Isoforms during Avian Myogenesis In Vitro [PDF]

, 2010
BACKGROUND. Multiple types of fast and slow skeletal muscle fibers form during early embryogenesis in vertebrates. In zebrafish, formation of the earliest slow myofibers in fin muscles requires expression of the zinc-finger transcriptional repressor ...
Ardelt, Magdalena, Beermann, Mary Lou, Girgenrath, Mahasweta, Miller, Jeffrey Boone   +3 more
core   +4 more sources

Coupling between Myogenesis and Angiogenesis during Skeletal Muscle Regeneration Is Stimulated by Restorative Macrophages

Stem Cell Reports, 2017
Summary: In skeletal muscle, new functions for vessels have recently emerged beyond oxygen and nutrient supply, through the interactions that vascular cells establish with muscle stem cells. Here, we demonstrate in human and mouse that endothelial cells (
Claire Latroche, Michèle Weiss-Gayet, Laurent Muller, Cyril Gitiaux, Pascal Leblanc, Sophie Liot, Sabrina Ben-Larbi, Rana Abou-Khalil, Nicolas Verger, Paul Bardot, Mélanie Magnan, Fabrice Chrétien, Rémi Mounier, Stéphane Germain, Bénédicte Chazaud   +14 more
doaj   +1 more source